546 research outputs found
The Interior Dynamics of Water Planets
The ever-expanding catalog of detected super-Earths calls for theoretical
studies of their properties in the case of a substantial water layer. This work
considers such water planets with a range of masses and water mass fractions (2
to 5 M_Earth, 0.02% to 50% H2 O). First, we model the thermal and dynamical
structure of the near-surface for icy and oceanic surfaces, finding separate
regimes where the planet is expected to maintain a subsurface liquid ocean and
where it is expected to exhibit ice tectonics. Newly discovered exoplanets may
be placed into one of these regimes given estimates of surface temperature,
heat flux, and gravity. Second, we construct a parameterized convection model
for the underlying ice mantle of higher ice phases, finding that materials
released from the silicate iron core should traverse the ice mantle on the
timescale of 0.1 to 100 megayears. We present the dependence of the overturn
times of the ice mantle and the planetary radius on total mass and water mass
fraction. Finally, we discuss the implications of these internal processes on
atmospheric observables.Comment: 9 page 4 figure
Dynamic masses for the close PG1159 binary SDSSJ212531.92-010745.9
SDSSJ212531.92-010745.9 is the first known PG1159 star in a close binary with
a late main sequence companion allowing a dynamical mass determination. The
system shows flux variations with a peak-to-peak amplitude of about 0.7 mag and
a period of about 6.96h. In August 2007, 13 spectra of SDSSJ212531.92-010745.9
covering the full orbital phase range were taken at the TWIN 3.5m telescope at
the Calar Alto Observatory (Alm\'{e}ria, Spain). These confirm the typical
PG1159 features seen in the SDSS discovery spectrum, together with the Balmer
series of hydrogen in emission (plus other emission lines), interpreted as
signature of the companion's irradiated side. A radial velocity curve was
obtained for both components. Using co-added radial-velocity-corrected spectra,
the spectral analysis of the PG1159 star is being refined.
The system's lightcurve, obtained during three seasons of photometry with the
G\"ottingen 50cm and T\"ubingen 80cm telescopes, was fitted with both the
NIGHTFALL and PHOEBE binary simulation programs. An accurate mass determination
of the PG1159 component from the radial velocity measurements requires to first
derive the inclination, which requires light curve modelling and yields further
constraints on radii, effective temperature and separation of the system's
components. From the analysis of all data available so far, we present the
possible mass range for the PG1159 component of SDSSJ212531.92-010745.9.Comment: 8 pages, in "White dwarfs", proceedings of the 16th European White
Dwarf Workshop, eds. E. Garcia-Berro, M. Hernanz, J. Isern, S. Torres, to be
published in J. Phys.: Conf. Se
A Model for the Information Content of Earnings Announcements
28 pages, 1 article*A Model for the Information Content of Earnings Announcements* (Schwager, Steven J.; Richardson, Gordon D.) 28 page
Self-diffusion in granular gases
The coefficient of self-diffusion for a homogeneously cooling granular gas
changes significantly if the impact-velocity dependence of the restitution
coefficient is taken into account. For the case of a constant
the particles spread logarithmically slow with time, whereas the
velocity dependent coefficient yields a power law time-dependence. The impact
of the difference in these time dependences on the properties of a freely
cooling granular gas is discussed.Comment: 6 pages, no figure
Application of Pulsed Field Gel Electrophoresis to Determine γ-ray-induced Double-strand Breaks in Yeast Chromosomal Molecules
The frequency of DNA double-strand breaks (dsb) was determined in yeast cells exposed to γ-rays under anoxic conditions. Genomic DNA of treated cells was separated by pulsed field gel electrophoresis, and two different approaches for the evaluation of the gels were employed: (1) The DNA mass distribution profile obtained by electrophoresis was compared to computed profiles, and the number of DSB per unit length was then derived in terms of a fitting procedure; (2) hybridization of selected chromosomes was performed, and a comparison of the hybridization signals in treated and untreated samples was then used to derive the frequency of dsb
Coefficient of normal restitution of viscous particles and cooling rate of granular gases
We investigate the cooling rate of a gas of inelastically interacting
particles. When we assume velocity dependent coefficients of restitution the
material cools down slower than with constant restitution. This behavior might
have large influence to clustering and structure formation processes.Comment: 3 figures, Phys. Rev. E (in press
Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation
Background: Breast cancer risk increases drastically in individuals carrying a germline BRCA1 mutation. The exposure to ionizing radiation for diagnostic or therapeutic purposes of BRCA1 mutation carriers is counterintuitive, since BRCA1 is active in the DNA damage response pathway. The aim of this study was to investigate whether healthy BRCA1 mutations carriers demonstrate an increased radiosensitivity compared with healthy individuals.
Methods: We defined a novel radiosensitivity indicator (RIND) based on two endpoints measured by the G2 micronucleus assay, reflecting defects in DNA repair and G2 arrest capacity after exposure to doses of 2 or 4 Gy. We investigated if a correlation between the RIND score and nonsense-mediated decay (NMD) could be established.
Results: We found significantly increased radiosensitivity in the cohort of healthy BRCA1 mutation carriers compared with healthy controls. In addition, our analysis showed a significantly different distribution over the RIND scores (p = 0.034, Fisher’s exact test) for healthy BRCA1 mutation carriers compared with non-carriers: 72 % of mutation carriers showed a radiosensitive phenotype (RIND score 1–4), whereas 72 % of the healthy volunteers showed no radiosensitivity (RIND score 0). Furthermore, 28 % of BRCA1 mutation carriers had a RIND score of 3 or 4 (not observed in control subjects). The radiosensitive phenotype was similar for relatives within several families, but not for unrelated individuals carrying the same mutation. The median RIND score was higher in patients with a mutation leading to a premature termination codon (PTC) located in the central part of the gene than in patients with a germline mutation in the 5′ end of the gene.
Conclusions: We show that BRCA1 mutations are associated with a radiosensitive phenotype related to a compromised DNA repair and G2 arrest capacity after exposure to either 2 or 4 Gy. Our study confirms that haploinsufficiency is the mechanism involved in radiosensitivity in patients with a PTC allele, but it suggests that further research is needed to evaluate alternative mechanisms for mutations not subjected to NMD
Simulation for the oblique impact of a lattice system
The oblique collision between an elastic disk and an elastic wall is
numerically studied.
We investigate the dependency of the tangential coefficient of restitution on
the incident angle of impact.
From the results of simulation, our model reproduces experimental results and
can be explained by a phenomenological theory of the oblique impact.Comment: 30 pages, 9 figures, submitted to J. Phys. Soc. Japa
Studies of the dose-effect relation
Dose-effect relations and, specifically, cell survival curves are surveyed with emphasis on the interplay of the random factors — biological variability, stochastic reaction of the cell, and the statistics of energy deposition —that co-determine their shape. The global parameters mean inactivation dose, , and coefficient of variance, V, represent this interplay better than conventional parameters. Mechanisms such as lesion interaction, misrepair, repair overload, or repair depletion have been invoked to explain sigmoid dose dependencies, but these notions are partly synonymous and are largely undistinguishable on the basis of observed dose dependencies. All dose dependencies reflect, to varying degree, the microdosimetric fluctuations of energy deposition, and these have certain implications, e.g. the linearity of the dose dependence at small doses, that apply regardless of unresolved molecular mechanisms of cellular radiation action
The minimization of mechanical work in vibrated granular matter
Experiments and computer simulations are carried out to investigate phase separation in a granular gas under vibration. The densities of the dilute and the dense phase are found to follow a lever rule and obey an equation of state. Here we show that the Maxwell equal-areas construction predicts the coexisting pressure and binodal densities remarkably well, even though the system is far from thermal equilibrium. This construction can be linked to the minimization of mechanical work associated with density fluctuations without invoking any concept related to equilibrium-like free energies
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