Amendment of Heuts-Selen's lotsizing and sequencing heuristic for single stage process manufacturing systems

Productivity;Production Scheduling;Manufacturing;production

On the Determinations of Class-Based Storage Assignments in AS/RS having two I/O Locations

This paper presents the use and extension of a geometrical-based algorithmic approach for determining the expected S/R machine cycle times, and therefore warehouse throughput, for class-based storage assignment layouts in an AS/RS.The approach was designed for the purpose of solving a practical storage assignment design problem for a major European manufacturer.The algorithm may be used to layout racks that are either "square-in-time (SIT)" or "non-square in time (NSIT)" with single or multiple I/O points.It is believed that use of this approach can result in the expedient evaluation of warehouse throughput resulting from new layouts, or re-layouts, of AS/R system racks, thus making these systems more appealing for use in integrated supply chain systems in general.production management;manufacturing;supply chain mangement;warehousing;storage

A Gemoetrical Approach to Computing Expected Cycle Times for Class-Based Storage Layouts in AS/RS

An exact, geometry-based analytical model is presented that can be used to compute the expected cycle time for a storage/retrieval (S/R) machine, executing single-commands, dual-commands, or both, in a rack structure that has been laid out in pre-specified storage zones for classes of goods.The rack may be either square-in-time or non-square-in-time.The approach is intuitively appealing, and it does not assume any certain layout shape, such as traditional "L-shaped" class layouts.The model has been coded in Turbo Pascal, and can be used by designers as a tool for quickly evaluating alternative layout configurations with respect to expected S/R cycle time in an AS/RS, and thereby the throughput of an automated warehouse over time.This model has been successfully applied in a major manufacturing plant in Europe to evaluate reconfigurations of their rack storage layouts over the past five years.Automated storage and retrieval systems;AS/RS;class-based storage.

Production Planning and Inventory Control in the Pre-deco Industry

Keywords: batch process industry; inventory control; production planning;

Export of functional Streptomyces coelicolor alditol oxidase to the periplasm or cell surface of Escherichia coli and its application in whole-cell biocatalysis

Streptomyces coelicolor A3(2) alditol oxidase (AldO) is a soluble monomeric flavoprotein in which the flavin cofactor is covalently linked to the polypeptide chain. AldO displays high reactivity towards different polyols such as xylitol and sorbitol. These characteristics make AldO industrially relevant, but full biotechnological exploitation of this enzyme is at present restricted by laborious and costly purification steps. To eliminate the need for enzyme purification, this study describes a whole-cell AldO biocatalyst system. To this end, we have directed AldO to the periplasm or cell surface of Escherichia coli. For periplasmic export, AldO was fused to endogenous E. coli signal sequences known to direct their passenger proteins into the SecB, signal recognition particle (SRP), or Twin-arginine translocation (Tat) pathway. In addition, AldO was fused to an ice nucleation protein (INP)-based anchoring motif for surface display. The results show that Tat-exported AldO and INP-surface-displayed AldO are active. The Tat-based system was successfully employed in converting xylitol by whole cells, whereas the use of the INP-based system was most likely restricted by lipopolysaccharide LPS in wild-type cells. It is anticipated that these whole-cell systems will be a valuable tool for further biological and industrial exploitation of AldO and other cofactor-containing enzymes.

A Modelling Framework for Energy-Management and Eco-Driving Problems using Convex Relaxations

This paper presents a convex optimization framework for eco-driving and vehicle energy management problems. We will first show that several types of eco-driving and vehicle energy management problems can be modelled using the same notions of energy storage buffers and energy storage converters that are connected to a power network. It will be shown that these problems can be formulated as optimization problems with linear cost functions and linear dynamics, and nonlinear constraints representing the power converters. We will show that under some mild conditions, the (non-convex) optimization problem has the same (globally) optimal solution as a convex relaxation. This means that the problems can be solved efficiently and that the solution is guaranteed to be globally optimal. Finally, a numerical example of the eco-driving problem is used to illustrate this claim

Production Planning and Inventory Control in the Pre-deco Industry

Keywords: batch process industry; inventory control; production planning;

On the Determinations of Class-Based Storage Assignments in AS/RS having two I/O Locations

This paper presents the use and extension of a geometrical-based algorithmic approach for determining the expected S/R machine cycle times, and therefore warehouse throughput, for class-based storage assignment layouts in an AS/RS.The approach was designed for the purpose of solving a practical storage assignment design problem for a major European manufacturer.The algorithm may be used to layout racks that are either "square-in-time (SIT)" or "non-square in time (NSIT)" with single or multiple I/O points.It is believed that use of this approach can result in the expedient evaluation of warehouse throughput resulting from new layouts, or re-layouts, of AS/R system racks, thus making these systems more appealing for use in integrated supply chain systems in general