92 research outputs found
Energy consumption of milking pump controlled by frequency convertor during milking cycle
ArticleThe article deals with selected parameters affecting the energy consumption of a
vacuum pump in a milking system during the whole milking cycle in variants with and without
regulation by a frequency convertor. When put into practice, the latest research of creation,
control and stabilization of vacuum in milking devices allows dairy farmers to obtain a vacuum
system that ensures maximum stability of milking pressure, which is a basic requirement affecting
the health of dairy cows. The choice of vacuum system prioritizes in particular high performance,
maximum operational reliability, minimum maintenance, long service life, environmental
friendliness and economy. The vacuum pump was a Roots vacuum pump with a rotary piston
which is typical for this use. Use of a frequency convertor significantly affected the efficiency of
this pump for control of vacuum pressure level and pump performance by varying the rotation
frequency according to the actual airflow requirement. Using this control system, only as much
vacuum pressure is produced as necessary. By measurement of an experimental setup, it was
found that the average power requirement of a setup with a control valve was 3.8 kW compared
to 1.7 kW in the case of the variant with frequency convertor. Measurements and calculations
have shown that this system is capable of saving more than 50% of electric energy
Substrate protein folds while it is bound to the ATP-independent chaperone Spy
Chaperones assist the folding of many proteins in the cell. While the most well studied chaperones use cycles of ATP binding and hydrolysis to assist protein folding, a number of chaperones have been identified that promote protein folding in the absence of highenergy cofactors. Precisely how ATP-independent chaperones accomplish this feat is
unclear. Here we have characterized the kinetic mechanism of substrate folding by the small, ATP-independent chaperone, Spy. Spy rapidly associates with its substrate, Immunity protein 7 (Im7), eliminating its potential for aggregation. Remarkably, Spy then allows Im7 to fully fold into its native state while remaining bound to the surface of the chaperone. These results establish a potentially widespread mechanism whereby ATP-independent chaperones can assist in protein refolding. They also provide compelling evidence that substrate proteins can fold while continuously bound to a chaperone
Macroeconomic policy interaction: State dependency and implications for financial stability in UK: A systemic review
The association between economic and financial stabilities and influence of macroeconomic policies on the financial sector creates scope of active policy role in financial stability. As a contribution to the existing body of knowledge, this study has analysed the implications of macroeconomic policy interaction/coordination for financial stability, proxied by financial assets, i.e. equity and bonds price oscillation. The critical review and analysis of the existing literature on the subject suggests that there is also ample evidence of interdependence between monetary and fiscal policies and this interrelation necessitates coordination between them for the sake of financial stability. There is also a case for analysing the symmetry of financial markets responses to macroeconomic policy interaction. On methodological and empirical grounds, it is vital to test the robustness of policy recommendations to overcome the limitation of a single empirical approach (Jeffrey–Lindley’s paradox). Hence, the Frequentist and Bayesian approaches should be used in commentary manner. The policy interaction and optimal policy combination should also be analysed in the context of institutional design and major financial events to gain insight into the implications of policy interaction in the periods of stable economic and financial environments as well as period of financial and economic distress
Influence of Camera Setting on Vehicle-to-Vehicle VLC Employing Undersampled Phase Shift On-Off Keying
This paper focuses on the performance analysis of a camera based vehicle-to-vehicle visible light communication system employing undersampled phase shift on-off keying modulation under interference scenario. Two Nissan Qashqai front lights with daylight running light emitting diodes based lamps are used for communications. The bit error rate (BER) performance of the proposed system is experimentally measured for a transmission span up to 24m focusing mostly on the side interference due to reflections. Based on experimental data we demonstrate reduction of the system performance due to the side reflection and illumination of the detector by other light sources which has to taken into account during further data processing. We provide with further statistics for particular shuter speed and transmitter power setting and discus BER improvement especially to meet FEC via the method of adaptive region of interest
Chaperones convert the energy from ATP into the nonequilibrium stabilization of native proteins.
During and after protein translation, molecular chaperones require ATP hydrolysis to favor the native folding of their substrates and, under stress, to avoid aggregation and revert misfolding. Why do some chaperones need ATP, and what are the consequences of the energy contributed by the ATPase cycle? Here, we used biochemical assays and physical modeling to show that the bacterial chaperones GroEL (Hsp60) and DnaK (Hsp70) both use part of the energy from ATP hydrolysis to restore the native state of their substrates, even under denaturing conditions in which the native state is thermodynamically unstable. Consistently with thermodynamics, upon exhaustion of ATP, the metastable native chaperone products spontaneously revert to their equilibrium non-native states. In the presence of ATPase chaperones, some proteins may thus behave as open ATP-driven, nonequilibrium systems whose fate is only partially determined by equilibrium thermodynamics
Myelin-derived and putative molecular mimic peptides share structural properties in aqueous and membrane-like environments
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