14,973 research outputs found

    Experimental determination of pressure drop and flow characteristics of dilute gas-solid suspensions

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    Loading ratio, glass particle size, and air Reynolds number effects on pressure drop and flow characteristics of air-solid suspension in turbulent pipe flo

    Risk and injury portrayal in boys' and girls' favourite television programmes

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    Objectives: To analyse the injury-related content of children’s television programmes preferred by boys and by girls, and to determine whether there are more televised models of unsafe behaviour in programmes preferred by boys. Methods: Parents of 4–11-year-old children identified their children’s favourite television programmes. Content analysis of 120 episodes of children’s favourite programmes was used to quantify safe and risky behaviours, actual injuries and potential injuries. The gender of the characters portraying the behaviours was also analysed. Results: More risky behaviour was portrayed in the boys’ favourite programmes (mean per episode =6.40) than in the girls’ favourite programmes (mean=2.57). There were almost twice as many potential injuries (n=310) as actual injuries (n=157). Potential injuries were portrayed more often by male characters (mean=1.92) than female characters (mean=0.98), mostly in the boys’ favourite programmes. Actual injuries occurred more often to male characters (mean=1.04) than to female characters (mean=0.27) overall. Conclusions: Television programmes preferred by this sample of boys portrayed male role models engaging in risky behaviours and injuries more often than the programmes preferred by the sample of girls

    The effects of peer influence on adolescent pedestrian road-crossing decisions

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    Objective: Adolescence is a high-risk period for pedestrian injury. It is also a time of heightened susceptibility to peer influence. The aim of this research was to examine the effects of peer influence on the pedestrian road-crossing decisions of adolescents. Methods: Using 10 videos of road-crossing sites, 80 16- to 18-year-olds were asked to make pedestrian road-crossing decisions. Participants were assigned to one of 4 experimental conditions: negative peer (influencing unsafe decisions), positive peer (influencing cautious decisions), silent peer (who observed but did not comment), and no peer (the participant completed the task alone). Peers from the adolescent’s own friendship group were recruited to influence either an unsafe or a cautious decision. Results: Statistically significant differences were found between peer conditions. Participants least often identified safe road-crossing sites when accompanied by a negative peer and more frequently identified dangerous road-crossing sites when accompanied by a positive peer. Both cautious and unsafe comments from a peer influenced adolescent pedestrians’ decisions. Conclusions: These findings showed that road-crossing decisions of adolescents were influenced by both unsafe and cautious comments from their peers. The discussion highlighted the role that peers can play in both increasing and reducing adolescent risk-taking

    Identification of a New Family of Enzymes with Potential \u3cem\u3eO\u3c/em\u3e-acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria

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    Background: The metabolism of the rigid bacterial cell wall heteropolymer peptidoglycan is a dynamic process requiring continuous biosynthesis and maintenance involving the coordination of both lytic and synthetic enzymes. The O-acetylation of peptidoglycan has been proposed to provide one level of control on these activities as this modification inhibits the action of the major endogenous lytic enzymes, the lytic transglycosylases. The O-acetylation of peptidoglycan also inhibits the activity of the lysozymes which serve as the first line of defense of host cells against the invasion of bacterial pathogens. Despite this central importance, there is a dearth of information regarding peptidoglycan O-acetylation and nothing has previously been reported on its de-acetylation. Results: Homology searches of the genome databases have permitted this first report on the identification of a potential family of O-Acetylpeptidoglycan esterases (Ape). These proteins encoded in the genomes of a variety of both Gram-negative and Gram-positive bacteria, including a number of important human pathogens such as species of Neisseria, Helicobacter, Campylobacter, and Bacillus anthracis, have been organized into three families based on amino acid sequence similarities with family 1 being further divided into three sub-families. The genes encoding these proteins are shown to be clustered with Peptidoglycan O-acetyltransferases (Pat) and in some cases, together with other genes involved in cell wall metabolism. Representative bacteria that encode the Ape proteins were experimentally shown to produce O-acetylated peptidoglycan. Conclusion: The hypothetical proteins encoded by the pat and ape genes have been organized into families based on sequence similarities. The Pat proteins have sequence similarity to Pseudomonas aeruginosa AlgI, an integral membrane protein known to participate in the O-acetylation of the exopolysaccaride, alginate. As none of the bacteria that harbor the pat genes produce alginate, we propose that the Pat proteins serve to O-acetylate peptidoglycan which is known to be a maturation event occurring in the periplasm. The Ape sequences have amino acid sequence similarity to the CAZy CE 3 carbohydrate esterases, a family previously known to be composed of only O-acetylxylan esterases. They are predicted to contain the α/β hydrolase fold associated with the GDSL and TesA hydrolases and they possess the signature motifs associated with the catalytic residues of the CE3 esterases. Specific signature sequence motifs were identified for the Ape proteins which led to their organization into distinct families. We propose that by expressing both Pat and Ape enzymes, bacteria would be able to obtain a high level of localized control over the degradation of peptidoglycan through the attachment and removal of O-linked acetate. This would facilitate the efficient insertion of pores and flagella, localize spore formation, and control the level of general peptidoglycan turnover

    Modeling the adoption and use of social media by nonprofit organizations

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    This study examines what drives organizational adoption and use of social media through a model built around four key factors - strategy, capacity, governance, and environment. Using Twitter, Facebook, and other data on 100 large US nonprofit organizations, the model is employed to examine the determinants of three key facets of social media utilization: 1) adoption, 2) frequency of use, and 3) dialogue. We find that organizational strategies, capacities, governance features, and external pressures all play a part in these social media adoption and utilization outcomes. Through its integrated, multi-disciplinary theoretical perspective, this study thus helps foster understanding of which types of organizations are able and willing to adopt and juggle multiple social media accounts, to use those accounts to communicate more frequently with their external publics, and to build relationships with those publics through the sending of dialogic messages.Comment: Seungahn Nah and Gregory D. Saxton. (in press). Modeling the adoption and use of social media by nonprofit organizations. New Media & Society, forthcomin

    Culture change in a professional sports team: Shaping environmental contexts and regulating power

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    Although high performing cultures are crucial for the enduring success of professional sport performance teams, theoretical and practical understanding of how they are established and sustained is lacking. To develop knowledge in this area, a case study was undertaken to examine the key mechanisms and processes of a successful culture change programme at English Rugby Union’s Leeds Carnegie. Exploring the change process from a 360 degree perspective, semi-structured interviews were conducted with team management, one specialist coach, six players, and the CEO. Analysed and explained through decentred theory, results revealed that culture change was effectively facilitated by team management: a) subtly and covertly shaping the physical, structural, and psychosocial context in which support staff and players made performance-impacting choices, and b) regulating the ‘to and fro’ of power which characterises professional sport performance teams. Decentred theory is also supported as an effective framework for culture change study

    Immigrants and the Community

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    First in a series based on the research project "Integrating the Needs of Immigrant Workers and Rural Communities," which attempts to inform New York communities about the nature and consequences of increasing immigrant settlement.Many upstate New York communities have experienced population loss and decline in the last decade. Increasing numbers of immigrants have settled in many of these communities, which poses possible community development challenges and opportunities. Because each community must address these issues in its own way, this report is intended to make communities aware of changes in their populations and highlight issues they may choose to address.USDA Fund for Rural America (grant #2001-36201-11283) and Cornell University Agricultural Experiment Station (grant #33452

    Immigrants and the Community: Farmworkers with Families

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    Second in a series based on the research project ?Integrating the Needs of Immigrant Workers and Rural Communities,? which attempts to inform New York communities about the nature and consequences of increasing immigrant settlement.America's hired farm workforce has changed considerably in the last decade. The most apparent change has been its "latinization" during the past two decades. This is largely a consequence of large numbers of Mexicans coming to the United States to work. Although Mexican immigrants work in numerous industries across the American landscape, they are especially important in agriculture. There has been a growing tendency of farmworkers to settle in rural communities together with their immediate family. But how and to what extent does community integration occur? How do foreigners who have little familiarity with American culture become integrated into the community? Answers to these questions have practical importance to farmers interested in retaining their workforce, service providers working to improve farmworker well-being and communities interested in helping the new residents contribute to community development. To help us understand the factors that both promote and limit the integration of immigrants into rural communities, we chose for study five New York agricultural communities in different economic and social contexts that have relied heavily on hired farm labor. Each community has a minority population of some significance and a history of immigrant farmworkers settling there

    Anisotropic splitting of intersubband spin plasmons in quantum wells with bulk and structural inversion asymmetry

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    In semiconductor heterostructures, bulk and structural inversion asymmetry and spin-orbit coupling induce a k-dependent spin splitting of valence and conduction subbands, which can be viewed as being caused by momentum-dependent crystal magnetic fields. This paper studies the influence of these effective magnetic fields on the intersubband spin dynamics in an asymmetric n-type GaAs/AlGaAs quantum well. We calculate the dispersions of intersubband spin plasmons using linear response theory. The so-called D'yakonov-Perel' decoherence mechanism is inactive for collective intersubband excitations, i.e., crystal magnetic fields do not lead to decoherence of spin plasmons. Instead, we predict that the main signature of bulk and structural inversion asymmetry in intersubband spin dynamics is a three-fold, anisotropic splitting of the spin plasmon dispersion. The importance of many-body effects is pointed out, and conditions for experimental observation with inelastic light scattering are discussed.Comment: 8 pages, 6 figure
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