Monitoring Challenges and Approaches for P2P File-Sharing Systems

Since the release of Napster in 1999, P2P file-sharing has enjoyed a dramatic rise in popularity. A 2000 study by Plonka on the University of Wisconsin campus network found that file-sharing accounted for a comparable volume of traffic to HTTP, while a 2002 study by Saroiu et al. on the University of Washington campus network found that file-sharing accounted for more than treble the volume of Web traffic observed, thus affirming the significance of P2P in the context of Internet traffic. Empirical studies of P2P traffic are essential for supporting the design of next-generation P2P systems, informing the provisioning of network infrastructure and underpinning the policing of P2P systems. The latter is of particular significance as P2P file-sharing systems have been implicated in supporting criminal behaviour including copyright infringement and the distribution of illegal pornograph

The effect of undulations on Spontaneous Braid formation

This paper extends on a recent work where it was shown that forces dependent on the helical structure may cause two DNA molecules to spontaneously braid [R. Cortini et Al, Biophys. J. 101, 875 (2011)]. Here, bending fluctuations of DNA centre lines about the braid axis are incorporated into the braiding theory. The free energy of the pair of molecules is recalculated and compared to its value without incorporating undulations. We find that the loss of configurational entropy due to confinement of the molecules in the braid is rather high. This contribution to the Free Energy pushes up the amount of attraction needed for spontaneous braiding due to helix dependant forces. The theory will be further developed for plectonemes and braids under mechanical forces, in later work.Comment: Main Text+Supplemental material. 5 figure

Complete gradient-LC-ESI system on a chip for protein analysis

This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed separation column, and an ESI nozzle. We also present the successful on-chip separation of protein digests by reverse phase (RP)-LC coupled with on-line mass spectrometer (MS) analysis

Temperature Effects on Development of Three Cereal Aphid Parasitoids (Hymenoptera: Aphidiidae)

Temperature is an important climatological variable that influences the biology and ecology of insects. Poor climatic adaptation can limit the effectiveness of parasitic insects in biological control. Two exotic parasites (Syrian Diaeretiella rapae (M\u27Intosh) and Argentinean Aphidius colemani Viereck) imported for biological control of the Russian wheat aphid, Diuraphis noxia (Mordvilko), and one native parasite (Diaeretiella rapae) were reared in growth chambers in three fluctuating temperature regimes with average daily temperatures of 12, 18, and 24°C. Estimates of temperature thresholds for immature development were 3.3, 3.5, and 2.8°C, for Oklahoman D. rapae, Syrian D. rapae, and A. colemani, respectively. Estimates of thermal require- ments for development from egg to adult were 297, 278, and 301 degree-days for the three parasitoids. Dry weights of adults reared in different fluctuating temperature regimes did not differ significantly among sexes, but adults from regimes with low average temperatures of 12 and 18°C had significantly greater weights than those reared in a regime with an average temperature of 24°C. Results suggest that developmental response to temperature will not limit the effectiveness of the exotic parasites in biological control