18 research outputs found
Development and implementation of the quality control panel of RT-PCR and real-time RT-PCR for avian influenza A (H5N1) surveillance network in mainland China
Comparison of instrumental and chemical-analytical principles of the systems Ektachem, Reflotron and Seralyzer
Interference of dextran in biuret-type assays of serum proteins
Dextran interference in biuret-type assays of total serum proteins was investigated in a Belgian National External Quality Assurance Survey with 256 participants. In vitro supplementation of therapeutic (10% Gentran 70) dextran concentrations showed a broadly varying (from 0 to 20%) negative interference. The analytical interference was found to depend on both the sodium hydroxide and tartrate concentrations in the reagent formulation. The dry chemistry biuret method was not affected by the dextran interference. In a number of cases, the effects observed may be of clinical importance. Both clinicians and laboratory staff should be aware of the persistence of this analytical problem</p
Accuracy-based assessment of proficiency testing results with serum from single donations: Possibilities and limitations.
Positive Interference of Merthiolate in the Tdx Digoxin Assay in Control Samples - Used in the Belgian External Quality Assessment (eqa) Scheme
We investigated the possible origin of the spuriously high results observed with the Abbott TDx Immunoassay in the 1991 Belgian external quality assessment scheme for digoxin. The present work ascribes this discrepancy to a matrix effect induced by the addition of merthiolate as preservative to the control samples. It consequently stresses the importance of avoiding the use of this compound for preparing such samples
Positive Interference of Merthiolate in the Tdx Digoxin Assay in Control Samples - Used in the Belgian External Quality Assessment (eqa) Scheme
We investigated the possible origin of the spuriously high results observed with the Abbott TDx Immunoassay in the 1991 Belgian external quality assessment scheme for digoxin. The present work ascribes this discrepancy to a matrix effect induced by the addition of merthiolate as preservative to the control samples. It consequently stresses the importance of avoiding the use of this compound for preparing such samples
