203 research outputs found
Mediators of the relationship between attachment and dispositional mindfulness in adolescents
ObjectivesConverging studies have confirmed a robust relationship between attachment and mindfulness, leading to the proposition that dispositional mindfulness originates from early interpersonal relationships. Despite this assertion, few studies have examined these relationships in adolescents and young adults. Theoretical linkages between mindfulness, attachment, relationships, and self-regulation suggest that attachment may be linked to mindfulness via self-regulatory capacity. This study examined the direct effect of attachment on dispositional mindfulness in adolescents and young adults, as well as indirect effects via attentional control and emotion regulation.MethodsParticipants were 421 adolescents and young people age 12–24 years (M = 17, SD = 4.10). They completed a self-report survey measuring attachment anxiety, attachment avoidance, dispositional mindfulness, attentional control (AC), and emotion regulation (ER).ResultsThere was a moderate effect of attachment anxiety 95% CI [− 1.45, − 0.93], and a small effect of attachment avoidance 95% CI [− 1.27, − 0.44] on mindfulness. Attachment anxiety was indirectly related to mindfulness via AC, 95% CI [− 0.32, − 10], and ER, [− 0.80, − 0.41], as was attachment avoidance (AC, 95% CI [− 44, − 0.10], ER, 95% CI [− 0.52, − 0.19]. Serial mediation analyses revealed serial paths from AC through ER and ER through AC with small effect sizes relative to individual mediators.ConclusionsLevels of dispositional mindfulness in adolescents were linked to attachment insecurity dimensions through attention control and emotion regulation. Attachment dimension-specific differences were noted; for the anxiety dimension, emotion regulation exerts a stronger mediating effect
Postal survey of physicians and laboratories: Practices and perceptions of molecular oncology testing
<p>Abstract</p> <p>Background</p> <p>Molecular oncology testing (MOT) to detect genomic alterations underlying cancer holds promise for improved cancer care. Yet knowledge limitations regarding the delivery of testing services may constrain the translation of scientific advancements into effective health care.</p> <p>Methods</p> <p>We conducted a cross-sectional, self-administered, postal survey of active cancer physicians in Ontario, Canada (N = 611) likely to order MOT, and cancer laboratories (N = 99) likely to refer (i.e., referring laboratories) or conduct (i.e., testing laboratories) MOT in 2006, to assess respondents' perceptions of the importance and accessibility of MOT and their preparedness to provide it.</p> <p>Results</p> <p>54% of physicians, 63% of testing laboratories and 60% of referring laboratories responded. Most perceived MOT to be important for treatment, diagnosis or prognosis now, and in 5 years (61% – 100%). Yet only 45% of physicians, 59% of testing labs and 53% of referring labs agreed that patients in their region were receiving MOT that is indicated as a standard of care. Physicians and laboratories perceived various barriers to providing MOT, including, among 70% of physicians, a lack of clear guidelines regarding clinical indications, and among laboratories, a lack of funding (73% – 100%). Testing laboratories were confident of their ability to determine whether and which MOT was indicated (77% and 82% respectively), and perceived that key elements of formal and continuing education were helpful (75% – 100%). By contrast, minorities of physicians were confident of their ability to assess whether and which MOT was indicated (46% and 34% respectively), and while majorities considered various continuing educational resources helpful (68% – 75%), only minorities considered key elements of formal education helpful in preparing for MOT (17% – 43%).</p> <p>Conclusion</p> <p>Physicians and laboratory professionals were enthusiastic about the value of MOT for cancer care but most did not believe patients were gaining adequate access to clinically necessary testing. Further, our results suggest that many were ill equipped as individual stakeholders, or as a coordinated system of referral and interpretation, to provide MOT. These challenges should inspire educational, training and other interventions to ensure that developments in molecular oncology can result in optimal cancer care.</p
Mindfulness training for adolescents: A neurodevelopmental perspective on investigating modifications in attention and emotion regulation using event-related brain potentials
Plant sterols–enriched diet decreases small, dense LDL-cholesterol levels in children with hypercholesterolemia: a prospective study
Current status of the multinational Arabidopsis community
The multinational Arabidopsis research community is highly collaborative and over the past thirty years these activities have been documented by the Multinational Arabidopsis Steering Committee (MASC). Here, we (a) highlight recent research advances made with the reference plant Arabidopsis thaliana; (b) provide summaries from recent reports submitted by MASC subcommittees, projects and resources associated with MASC and from MASC country representatives; and (c) initiate a call for ideas and foci for the “fourth decadal roadmap,” which will advise and coordinate the global activities of the Arabidopsis research community
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