8,354 research outputs found
Lorentz-Violating Supergravity
The standard forms of supersymmetry and supergravity are inextricably wedded
to Lorentz invariance. Here a Lorentz-violating form of supergravity is
proposed. The superpartners have exotic properties that are not possible in a
theory with exact Lorentz symmetry and microcausality. For example, the bosonic
sfermions have spin 1/2 and the fermionic gauginos have spin 1. The theory is
based on a phenomenological action that is shown to follow from a simple
microscopic and statistical picture.Comment: 15 pages; to be published in Proceedings of Beyond the Desert 2003
(Castle Ringberg, Tegernsee, Germany, 9-14 June 2003), edited by H. V.
Klapdor-Kleingrothau
Clean up energy innovation
Countries need to agree clean energy definitions and baselines to track essential uplift of research investments to decarbonize the world’s energy supplies
Extracting causal rules from spatio-temporal data
The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-319-23374-1_2This paper is concerned with the problem of detecting causality in spatiotemporal data. In contrast to most previous work on causality, we adopt a logical rather than a probabilistic approach. By defining the logical form of the desired causal rules, the algorithm developed in this paper searches for instances of rules of that form that explain as fully as possible the observations found in a data set. Experiments with synthetic data, where the underlying causal rules are known, show that in many cases the algorithm is able to retrieve close approximations to the rules that generated the data. However, experiments with real data concerning the movement of fish in a large Australian river system reveal significant practical limitations, primarily as a consequence of the coarse granularity of such movement data. In response, instead of focusing on strict causation (where an environmental event initiates a movement event), further experiments focused on perpetuation (where environmental conditions are the drivers of ongoing processes of movement). After retasking to search for a different logical form of rules compatible with perpetuation, our algorithm was able to identify perpetuation rules that explain a significant proportion of the fish movements. For example, approximately one fifth of the detected long-range movements of fish over a period of six years were accounted for by 26 rules taking account of variations in water-level alone.EPSRCAustralian Research Council (ARC) under the Discovery Projects Schem
Surface-initiated growth of copper using isonicotinic acid-functionalized aluminum oxide surfaces
Isonicotinate self-assembled monolayers (SAM) were prepared on alumina surfaces (A) using isonicotinic acid (iNA). These functionalized layers (iNA-A) were used for the seeded growth of copper films (Cu-iNA-A) by hydrazine hydrate-initiated electroless deposition. The films were characterized by scanning electron microscopy (SEM), electron-dispersive X-ray spectroscopy, atomic force microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, and advancing contact angle measurements. The films are Cu0 but with surface oxidation, and show a faceted morphology, which is more textured (Rq = 460 ± 90 nm) compared to the SAM (Rq = 2.8 ± 0.5 nm). In contrast, growth of copper films by SnCl2/PdCl2 catalyzed electroless deposition, using formaldehyde (CH2O) as the reducing agent, shows a nodular morphology on top of a relatively smooth surface. No copper films are observed in the absence of the isonicotinate SAM. The binding of Cu2+ to the iNA is proposed to facilitate reduction to Cu0 and create the seed for subsequent growth. The films show good adhesion to the functionalized surface
An anomalous extinction law in the Cep OB3b young cluster: Evidence for dust processing during gas dispersal
© 2014. The American Astronomical Society. All rights reserved. We determine the extinction law through Cep OB3b, a young cluster of 3000 stars undergoing gas dispersal. The extinction is measured toward 76 background K giants identified with MMT/Hectospec spectra. Color excess ratios were determined toward each of the giants using V and R photometry from the literature, g, r, i, and z photometry from the Sloan Digital Sky Survey and J, H, and Ks photometry from the Two Micron All Sky Survey. These color excess ratios were then used to construct the extinction law through the dusty material associated with Cep OB3b. The extinction law through Cep OB3b is intermediate between the RV = 3.1 and RV = 5 laws commonly used for the diffuse atomic interstellar medium and dense molecular clouds, respectively. The dependence of the extinction law on line-of-sight AV is investigated and we find the extinction law becomes shallower for regions with AV > 2.5 mag. We speculate that the intermediate dust law results from dust processing during the dispersal of the molecular cloud by the cluster.Support for this work was provided by the National Science
Foundation award AST-1009564. This research has made
use of the NASA/IPAC Infrared Science Archive, which is
operated by the Jet Propulsion Laboratory, California Institute
of Technology, under contract with the National Aeronautics
and Space Administration. This publication makes
use of data products from the Two Micron All Sky Survey,
which is a joint project of the University of Massachusetts
and the Infrared Processing and Analysis Center/California
Institute of Technology, funded by the National Aeronautics
and Space Administration and the National Science Foundation
and JPL support from SAO/JPL SV4-74011. Funding for
SDSS-III has been provided by the Alfred P. Sloan Foundation,
the Participating Institutions, the National Science Foundation,
and the U.S. Department of Energy Office of Science.
The SDSS-III web site is http://www.sdss3.org/. SDSS-III is
managed by the Astrophysical Research Consortium for the Participating
Institutions of the SDSS-III Collaboration including
the University of Arizona, the Brazilian Participation Group,
Brookhaven National Laboratory, University of Cambridge,
Carnegie Mellon University, University of Florida, the French
Participation Group, the German Participation Group, Harvard
University, the Instituto de Astrofisica de Canarias, the Michigan
State/Notre Dame/JINA Participation Group, Johns Hopkins
University, Lawrence Berkeley National Laboratory, Max
Planck Institute for Astrophysics, Max Planck Institute for Extraterrestrial
Physics, New Mexico State University, New York
University, Ohio State University, Pennsylvania State University,
University of Portsmouth, Princeton University, the Spanish
Participation Group, University of Tokyo, University of
Utah, Vanderbilt University, University of Virginia, University
of Washington, and Yale University
The development of path integration: combining estimations of distance and heading
Efficient daily navigation is underpinned by path integration, the mechanism by which we use self-movement information to update our position in space. This process is well-understood in adulthood, but there has been relatively little study of path integration in childhood, leading to an underrepresentation in accounts of navigational development. Previous research has shown that calculation of distance and heading both tend to be less accurate in children as they are in adults, although there have been no studies of the combined calculation of distance and heading that typifies naturalistic path integration. In the present study 5-year-olds and 7-year-olds took part in a triangle-completion task, where they were required to return to the startpoint of a multi-element path using only idiothetic information. Performance was compared to a sample of adult participants, who were found to be more accurate than children on measures of landing error, heading error, and distance error. 7-year-olds were significantly more accurate than 5-year-olds on measures of landing error and heading error, although the difference between groups was much smaller for distance error. All measures were reliably correlated with age, demonstrating a clear development of path integration abilities within the age range tested. Taken together, these data make a strong case for the inclusion of path integration within developmental models of spatial navigational processing
Signal Propagation in Feedforward Neuronal Networks with Unreliable Synapses
In this paper, we systematically investigate both the synfire propagation and
firing rate propagation in feedforward neuronal network coupled in an
all-to-all fashion. In contrast to most earlier work, where only reliable
synaptic connections are considered, we mainly examine the effects of
unreliable synapses on both types of neural activity propagation in this work.
We first study networks composed of purely excitatory neurons. Our results show
that both the successful transmission probability and excitatory synaptic
strength largely influence the propagation of these two types of neural
activities, and better tuning of these synaptic parameters makes the considered
network support stable signal propagation. It is also found that noise has
significant but different impacts on these two types of propagation. The
additive Gaussian white noise has the tendency to reduce the precision of the
synfire activity, whereas noise with appropriate intensity can enhance the
performance of firing rate propagation. Further simulations indicate that the
propagation dynamics of the considered neuronal network is not simply
determined by the average amount of received neurotransmitter for each neuron
in a time instant, but also largely influenced by the stochastic effect of
neurotransmitter release. Second, we compare our results with those obtained in
corresponding feedforward neuronal networks connected with reliable synapses
but in a random coupling fashion. We confirm that some differences can be
observed in these two different feedforward neuronal network models. Finally,
we study the signal propagation in feedforward neuronal networks consisting of
both excitatory and inhibitory neurons, and demonstrate that inhibition also
plays an important role in signal propagation in the considered networks.Comment: 33pages, 16 figures; Journal of Computational Neuroscience
(published
Five supernova survey galaxies in the southern hemisphere. I. Optical and near-infrared database
The determination of the supernova (SN) rate is based not only on the number
of detected events, but also on the properties of the parent galaxy population.
This is the first paper of a series aimed at obtaining new, refined, SN rates
from a set of five SN surveys, by making use of a joint analysis of
near-infrared (NIR) data. We describe the properties of the 3838 galaxies that
were monitored for SNe events, including newly determined morphologies and
their DENIS and POSS-II/UKST I, 2MASS and DENIS J and Ks and 2MASS H
magnitudes. We have compared 2MASS, DENIS and POSS-II/UKST IJK magnitudes in
order to find possible systematic photometric shifts in the measurements. The
DENIS and POSS-II/UKST I band magnitudes show large discrepancies (mean
absolute difference of 0.4 mag), mostly due to different spectral responses of
the two instruments, with an important contribution (0.33 mag rms) from the
large uncertainties in the photometric calibration of the POSS-II and UKST
photographic plates. In the other wavebands, the limiting near infrared
magnitude, morphology and inclination of the galaxies are the most influential
factors which affect the determination of photometry of the galaxies.
Nevertheless, no significant systematic differences have been found between of
any pair of NIR magnitude measurements, except for a few percent of galaxies
showing large discrepancies. This allows us to combine DENIS and 2MASS data for
the J and Ks filters.Comment: 17 pages, 3 figures, 5 tables, published in Astrophysics, Vol. 52,
No. 1, 2009 (English translation of Astrofizika
Deletion of parasite immune modulatory sequences combined with immune activating signals enhances vaccine mediated protection against filarial nematodes
<p>Background: Filarial nematodes are tissue-dwelling parasites that can be killed by Th2-driven immune effectors, but that have evolved to withstand immune attack and establish chronic infections by suppressing host immunity. As a consequence, the efficacy of a vaccine against filariasis may depend on its capacity to counter parasite-driven immunomodulation.</p>
<p>Methodology and Principal Findings: We immunised mice with DNA plasmids expressing functionally-inactivated forms of two immunomodulatory molecules expressed by the filarial parasite Litomosoides sigmodontis: the abundant larval transcript-1 (LsALT) and cysteine protease inhibitor-2 (LsCPI). The mutant proteins enhanced antibody and cytokine responses to live parasite challenge, and led to more leukocyte recruitment to the site of infection than their native forms. The immune response was further enhanced when the antigens were targeted to dendritic cells using a single chain Fv-αDEC205 antibody and co-administered with plasmids that enhance T helper 2 immunity (IL-4) and antigen-presenting cell recruitment (Flt3L, MIP-1α). Mice immunised simultaneously against the mutated forms of LsALT and LsCPI eliminated adult parasites faster and consistently reduced peripheral microfilaraemia. A multifactorial analysis of the immune response revealed that protection was strongly correlated with the production of parasite-specific IgG1 and with the numbers of leukocytes present at the site of infection.</p>
<p>Conclusions: We have developed a successful strategy for DNA vaccination against a nematode infection that specifically targets parasite-driven immunosuppression while simultaneously enhancing Th2 immune responses and parasite antigen presentation by dendritic cells.</p>
Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants
Closely related HLA alleles presenting similar HIV-1 epitopes can be associated with variable clinical outcome. Here the authors report their findings on CD8+ T cell responses to the HIV-1 Gag-p24 TL9 immunodominant epitope in the context of closely related protective and less protective HLA alleles, and their differential effect on viral contro
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