Sympathy and Tenderness as Components of Dispositional Empathic Concern: Predicting Helping and Caring Behaviors

Recently, empathic concern was separated into the components of sympathy and tenderness (Lishner, Batson, & Huss, 2011). So far, these two emotional experiences have been assessed as episodic emotional responses, as the existent dispositional measures remain blind to such distinction. The aim of the present research is to develop and validate a dispositional measure that captures the personal disposition to feel sympathy, tenderness, and personal distress. This new scale is called Sympathy, Tenderness and Distress Dispositional Scale (SyTeD). In Study 1, we developed and tested the internal consistency and factor structure of the English version of the scale in the United States. In Study 2, we translated the scale into Spanish and tested its content and criterion validity in Spain. In Study 3, we tested the predictive validity of the sympathy-tenderness distinction within a helping vs. a care-based scenario in the United Kingdom (SyTeD-English version). In Study 4, we tested the predictive validity of the sympathy-tenderness distinction in a real helping situation in Spain (SyTeD-Spanish version). The results across these four studies suggest that the SyTeD is a useful measure of dispositional sympathy and tenderness that allows studying further different types of prosocial behavior (i.e., help vs. care)

Asymmetric hemisphere activation in tenderness: evidence from EEG signals

Emotions are processed asymmetrically by the human brain. Frontal alpha asymmetry (FAA) as measured by electroencephalographic (EEG) power in the alpha band (8-13 Hz), is a sensitive indicator of asymmetric brain activity in the frontal cortex. The current study aimed to analyze the frontal EEG asymmetries in terms of valence and motivational direction. We presented 37 participants with three film excerpts that were selected from the standard emotional film database to elicit three target emotions: tenderness, anger, and neutrality. Participants&#39; self-reports on their induced emotional responses and EEG signals were recorded and analyzed. The results showed that individuals displayed lower alpha power in the left hemisphere than the right hemisphere when they were watching a tender film, indicating that tenderness was positive and related to approach motivation. In contrast, when watching an angry movie, participants showed higher alpha power in the left hemisphere than the right hemisphere, suggesting that anger was negative and associated with withdrawal motivation. These findings help to link positive and approach-motivated tenderness with greater left hemispheric activation and state-anger with greater right hemispheric activation through the analysis of FAA.</p

Hsp70 and cardiac surgery: molecular chaperone and inflammatory regulator with compartmentalized effects

Open heart surgery is a unique model to study the interplay between cellular injury, regulation of inflammatory responses and tissue repair. Stress-inducible heat shock protein 70-kDa (Hsp70) provides a molecular link between these events. In addition to molecular chaperoning, Hsp70 exerts modulatory effects on endothelial cells and leukocytes involved in inflammatory networks. Hsp70 residing in the intracellular compartment is part of an inhibitory feedback loop that acts on nuclear factor kappaB (NF-κB). In contrast, extracellular Hsp70 is recognized by multiple germline-encoded immune receptors, e.g., Toll-like receptor (TLR) 2, TLR4, LOX-1, CD91, CD94, CCR5 and CD40. Hsp70 is thereby able to enhance chemotaxis, phagocytosis and cytolytic activity of innate immune cells and stimulate antigen-specific responses. These apparent contradictory pro- and anti-inflammatory effects of endogenous Hsp70 in the context of cardiac surgery are still not fully understood. An all-embracing model of the compartmentalized effects of endogenous Hsp70 in the orchestration of inflammatory responses in cardiac surgery is proposed