934 research outputs found
Ariel - Volume 3 Number 5
Editors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Paul Bialas
Robert Breckenridge
Lynne Porter
David Jacoby
Terry Burt
Mark Pearlman
Michael Leo
Mike LeWitt
Editors Emeritus
Delvyn C. Case., Jr.
Paul M. Fernhof
Ariel - Volume 3 Number 3
Editors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Stephen Flynn
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Paul Bialas
Robert Breckenridge
Lynne Porter
Milton Packer
Terry Burt
Mark Pearlman
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhoff
Mike Le
Ariel - Volume 3 Number 7
Editors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Paul Bialas
Robert Breckenridge
David Jacoby
Mike LeWitt
Terry Burt
Michael Leo
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Ariel - Volume 3 Number 1
Editors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Stephen Flynn
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Michael J. Blecker
Milton Parker
James J. Nocon
Lynne Porter
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Ariel - Volume 2 Number 7
Editors
Richard J. Bonanno
Robin A. Edwards
Associate Editors
Steven Ager
Stephen Flynn
Shep Dickman
Tom Williams
Lay-out Editor
Eugenia Miller
Contributing Editors
Michael J. Blecker
W. Cherry Light
James J. Nocon
Lynne Porter
Editors Emeritus
Delvyn C. Case, Jr.
Paul M. Fernhof
Ariel - Volume 4 Number 2
Editors
David A. Jacoby
Eugenia Miller
Tom Williams
Associate Editors
Paul Bialas
Terry Burt
Michael Leo
Gail Tenikat
Editor Emeritus and Business Manager
Richard J. Bonnano
Movie Editor
Robert Breckenridge
Staff
Richard Blutstein
Mary F. Buechler
Steve Glinks
Len Grasman
Alice M. Johnson
J. D. Kanofsky
Tom Lehman
Dave Mayer
Bernie Odd
A 4% Geometric Distance to the Galaxy NGC4258 from Orbital Motions in a Nuclear Gas Disk
The water maser in the mildly active nucleus in the nearby galaxy NGC4258
traces a thin, nearly edge-on, subparsec-scale Keplerian disk. Using the
technique of very long baseline interferometry, we have detected the proper
motions of these masers as they sweep in front of the central black hole at an
orbital velocity of about 1100 km/s. The average maser proper motion of 31.5
microarcseconds per year is used in conjunction with the observed acceleration
of the masers to derive a purely geometric distance to the galaxy of 7.2 +- 0.3
Mpc. This is the most precise extragalactic distance measured to date, and,
being independent of all other distance indicators, is likely to play an
important role in calibrating the extragalactic distance scale.Comment: 11 pages, 3 figures. Accepted for publication in Natur
The Planetary Nebula Luminosity Function at the Dawn of Gaia
The [O III] 5007 Planetary Nebula Luminosity Function (PNLF) is an excellent
extragalactic standard candle. In theory, the PNLF method should not work at
all, since the luminosities of the brightest planetary nebulae (PNe) should be
highly sensitive to the age of their host stellar population. Yet the method
appears robust, as it consistently produces < 10% distances to galaxies of all
Hubble types, from the earliest ellipticals to the latest-type spirals and
irregulars. It is therefore uniquely suited for cross-checking the results of
other techniques and finding small offsets between the Population I and
Population II distance ladders. We review the calibration of the method and
show that the zero points provided by Cepheids and the Tip of the Red Giant
Branch are in excellent agreement. We then compare the results of the PNLF with
those from Surface Brightness Fluctuation measurements, and show that, although
both techniques agree in a relative sense, the latter method yields distances
that are ~15% larger than those from the PNLF. We trace this discrepancy back
to the calibration galaxies and argue that, due to a small systematic error
associated with internal reddening, the true distance scale likely falls
between the extremes of the two methods. We also demonstrate how PNLF
measurements in the early-type galaxies that have hosted Type Ia supernovae can
help calibrate the SN Ia maximum magnitude-rate of decline relation. Finally,
we discuss how the results from space missions such as Kepler and Gaia can help
our understanding of the PNLF phenomenon and improve our knowledge of the
physics of local planetary nebulae.Comment: 12 pages, invited review at the conference "The Fundamental Cosmic
Distance Scale: State of the Art and Gaia Perspective", to appear in
Astrophysics and Space Scienc
Asher Lev at the Israel Museum: Stereotyping art and craft
Jesper Svartvik and Jakob Wirén (Eds.), Religious stereotyping and interreligious relations. New York: Palgrave Macmillan, 2013, reproduced with permission of Palgrave Macmillan. This extract is taken from the author's original manuscript and has not been edited. The definitive, published version of record is available here: http://www.palgrave.com/page/detail/religious-stereotyping-and-interreligious-relations-jesper-svartvik/?K=9781137344601 and http://www.palgraveconnect.com/pc/doifinder/10.1057/978113734267
Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC
Nucleotides and nucleosides are not only involved in cellular metabolism but also act extracellularly via P1 and P2 receptors, to elicit a wide variety of physiological and pathophysiological responses through paracrine and autocrine signalling pathways. For the first time, we have used an ion-pair reversed-phase high-performance liquid chromatography ultraviolet (UV)-coupled method to rapidly and simultaneously quantify 12 different nucleotides and nucleosides (adenosine triphosphate, adenosine diphosphate, adenosine monophosphate, adenosine, uridine triphosphate, uridine diphosphate, uridine monophosphate, uridine, guanosine triphosphate, guanosine diphosphate, guanosine monophosphate, guanosine): (1) released from a mouse renal cell line (M1 cortical collecting duct) and (2) in human biological samples (i.e., urine). To facilitate analysis of urine samples, a solid-phase extraction step was incorporated (overall recovery rate ? 98 %). All samples were analyzed following injection (100 ?l) into a Synergi Polar-RP 80 Å (250 × 4.6 mm) reversed-phase column with a particle size of 10 ?m, protected with a guard column. A gradient elution profile was run with a mobile phase (phosphate buffer plus ion-pairing agent tetrabutylammonium hydrogen sulfate; pH 6) in 2-30 % acetonitrile (v/v) for 35 min (including equilibration time) at 1 ml min(-1) flow rate. Eluted compounds were detected by UV absorbance at 254 nm and quantified using standard curves for nucleotide and nucleoside mixtures of known concentration. Following validation (specificity, linearity, limits of detection and quantitation, system precision, accuracy, and intermediate precision parameters), this protocol was successfully and reproducibly used to quantify picomolar to nanomolar concentrations of nucleosides and nucleotides in isotonic and hypotonic cell buffers that transiently bathed M1 cells, and urine samples from normal subjects and overactive bladder patients
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