36 research outputs found
How nurses and their work environment affect patient experiences of the quality of care: a qualitative study
Umfrageergebnisse zur Versorgungsrealität von Wirbelsäulenfrakturen im Kindes- und Jugendalter im deutschsprachigen Raum
Verletzungen der Wirbelsäule im Kindesalter - Ergebnisse einer nationalen Multicenterstudie mit 367 Patienten
Diagnostik und Therapie von Verletzungen der Brust- und Lendenwirbelsäule im Kindesalter - Empfehlungen der AG Wirbelsäulentrauma im Kindesalter
Verletzungen der Halswirbelsäule im Kindesalter - Ergebnisse einer Multicenterstudie an 367 Kindern
Molecular Recognition: Studies on the Synthesis of Methylene Pivotal Bisthiophene Carboxamide Derivatives as Ditopic Receptors for Suberic Acid
Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library
A chemical ligation method for construction of DNA-encoded small-molecule libraries has been developed. Taking advantage of the ability of the Klenow fragment of DNA polymerase to accept templates with triazole linkages in place of phosphodiesters, we have designed a strategy for chemically ligating oligonucleotide tags using cycloaddition chemistry. We have utilized this strategy in the construction and selection of a small molecule library, and successfully identified inhibitors of the enzyme soluble epoxide hydrolase
