Relationships between paranoid thinking, self-esteem and the menstrual cycle.

This study aimed to investigate whether paranoid experiences and levels of self-esteem fluctuate over the menstrual cycle and whether levels of self-esteem are lower when perceived persecution is felt to be deserved. Measures of anxiety, depression, persecution, deservedness and self-esteem were completed on-line by 278 women over their menstrual cycle. Responses were compared at the paramenstrual (3 days before and after menses onset) and mid-cycle phase. At the paramenstrual phase persecution, negative self-esteem, anxiety and depression were higher and positive self-esteem was lower than at mid-cycle. A greater proportion of women experienced persecution as deserved at the paramenstrual phase. This was associated with higher depression and negative self-esteem scores. Increased levels of deservedness significantly strengthened the relationship between persecution and negative, but not positive, self-esteem. These findings suggest that the paramenstrual phase is a time of vulnerability to increased paranoid experiences, an increased likelihood that feelings of persecution will feel deserved and lowered self-esteem. The findings support the view that interpersonal sensitivities may be key to menstrual cycle symptoms and have an impact on relationships. Further, the study illustrated that ideas developed for psychosis could make a valuable contribution to understanding and managing this aspect of menstruation-related distress

Belongingness in early secondary school: Key factors that primary and secondary schools need to consider

© 2015 Vaz et al. It is unknown if, and how, students redefine their sense of school belongingness after negotiating the transition to secondary school. The current study used longitudinal data from 266 students with, and without, disabilities who negotiated the transition from 52 primary schools to 152 secondary schools. The study presents the 13 most significant personal student and contextual factors associated with belongingness in the first year of secondary school. Student perception of school belongingness was found to be stable across the transition. No variability in school belongingness due to gender, disability or household-socio-economic status (SES) was noted. Primary school belongingness accounted for 22% of the variability in secondary school belongingness. Several personal student factors (competence, coping skills) and school factors (low-level classroom task-goal orientation), which influenced belongingness in primary school, continued to influence belongingness in secondary school. In secondary school, effort-goal orientation of the student and perception of their school's tolerance to disability were each associated with perception of school belongingness. Family factors did not influence belongingness in secondary school. Findings of the current study highlight the need for primary schools to foster belongingness among their students at an early age, and transfer students' belongingness profiles as part of the handover documentation. Most of the factors that influenced school belongingness before and after the transition to secondary are amenable to change

LIF-Dependent Signaling: New Pieces in the Lego

LIF, a member of the IL6 family of cytokine, displays pleiotropic effects on various cell types and organs. Its critical role in stem cell models (e.g.: murine ES, human mesenchymal cells) and its essential non redundant function during the implantation process of embryos, in eutherian mammals, put this cytokine at the core of many studies aiming to understand its mechanisms of action, which could benefit to medical applications. In addition, its conservation upon evolution raised the challenging question concerning the function of LIF in species in which there is no implantation. We present the recent knowledge about the established and potential functions of LIF in different stem cell models, (embryonic, hematopoietic, mesenchymal, muscle, neural stem cells and iPSC). We will also discuss EVO-DEVO aspects of this multifaceted cytokine

Weight and height prediction of immobilized patients Estimativa de peso e altura de pacientes hospitalizados e imobilizados

OBJECTIVE: To confirm the adequacy of the formula suggested in the literature and/or to develop appropriate equations for the Brazilian population of immobilized patients based on simple anthropometric measurements. METHODS: Hospitalized patients were submitted to anthropometry and methods to estimate weight and height of bedridden patients were developed by multiple linear regression. RESULTS: Three hundred sixty eight persons were evaluated at two hospital centers and five weight-predicting and two height-predicting equations were developed from the measurements obtained. Among the new equations developed, the simplest one for weight estimate was: Weight (kg) = 0.5759 x (arm circumference, cm) + 0.5263 x (abdominal circumference, cm) + 1.2452 x (calf circumference, cm) -4.8689 x (Sex, male = 1 and female = 2) -32.9241 (r = 0.94); and the one for height estimate was: Height (cm) = 58.6940 - 2.9740 x (Sex) -0.0736 x (age, years) + 0.4958 x (arm length, cm) + 1.1320 x (half- span, cm) (r = 0.88). The estimates thus calculated did not differ significantly from actual measurements, with p = 0.94 and 0.89 and a mean error of 6.0 and 2.1% for weight and height, respectively. CONCLUSION: We suggest that these equations can be used to estimate the weight and height of bedridden patients when necessary or when these parameters cannot be measured with a scale and a stadiometer.<br>OBJETIVO: Verificar a adequação das fórmulas sugeridas na literatura, e desenvolver equações preditivas de peso e altura para a população hospitalizada brasileira, a partir de medidas antropométricas usuais. MÉTODOS: Realizou-se antropometria e bioimpedância de pacientes hospitalizados. Por meio de regressão linear múltipla, desenvolveram-se fórmulas com o objetivo de prever o peso e a altura. Os resultados foram comparados com os obtidos de fórmulas da literatura e com as medidas reais. RESULTADOS: Foram avaliadas 368 pacientes e desenvolvidas equações preditivas do peso e da altura, ou seja: para estimativa de peso, peso (kg)= 0,5759 x (circunferência do braço, cm) + 0,5263 x (circunferência abdominal, cm) + 1,2452 x (circunferência da panturrilha, cm) -4,8689 x (Sexo, masculino= 1 feminino= 2) -32,9241 (r= 0,94, p<0.001); e altura (cm)= 58,6940 -2,9740 x (Sexo) -0,0736 x (idade, anos) + 0,4958 x (comprimento do braço, cm) + 1,1320 x (meia envergadura, cm) (r= 0,88, p<0.001). As estimativas realizadas foram estatisticamente semelhantes às medidas reais, p= 0,94 e 0,89 e erro médio de 6,0% e 2,1%, respectivamente para o peso e altura. Quando aplicadas as formulas preconizadas pela literatura, os resultados encontrados foram estatisticamente diferentes do real (p<0,001). CONCLUSÃO: Sugere-se que estas equações sejam utilizadas para prever peso e altura de pacientes acamados