Committees versus individuals: an experimental analysis of monetary policy decision-making

We report the results of an experimental analysis of monetary policy decision-making under uncertainty. A large sample of economically literate students from the London School of Economics played a simple monetary policy game, as both individuals and committees of five players. Our findings - that groups make better decisions than individuals - accord with previous work by Blinder and Morgan. The experiment also attempted to establish why group decision-making is superior: although some improvement was related to committees taking decisions by majority voting, a significant additional committee benefit was associated with members being able to share information and observe each other's voting behaviour.monetary policy, experimental economics, central banking, uncertainty

Committees Versus Individuals: An Experimental Analysis of Monetary Policy Decision Making

We report the results of an experimental analysis of monetary policy decision making under uncertainty. A large sample of economics students played a simple monetary policy game, both as individuals and in committees of five players. Our findings - that groups make better decisions than individuals - accord with previous work by Blinder and Morgan. We also attempt to establish why this is so. Some of the improvement is related to the ability of committees to strip out the effect of bad play, but there is a significant additional improvement, which we associate with players learning from each other’s interest rate decisions.Monetary policy; experimental economics; central banking; uncertainty

The effect of a targeted clinical toxicology training intervention on the diagnostic accuracy and management of paramedics exposed to clinical simulation: a repeated measures study

John Talbot and James Coulson, 'The effect of a targeted clinical toxicology training intervention on the diagnostic accuracy and management of paramedics exposed to clinical simulation: a repeated measures study', British Paramedic Journal, 2016, Vol. 1 (1): 15-25, © The Author(s) 2016.Background – As first contact practitioners in a variety of medical emergencies, paramedics are frequently required to manage a number of toxicological emergencies. Although mortality from poisonings is low, timely and appropriate management can help to prevent subsequent sequelae such as acute coronary syndromes in cocaine toxicity, dangerous arrhythmias after tricyclic antidepressant overdose and regurgitation of gastric content following opioid poisoning. Paramedics potentially have underdeveloped knowledge of toxic syndromes (toxidromes), instead relying on heuristics and experience to manage poisoning emergencies. Moreover formal teaching of pharmacology and toxicology on paramedic undergraduate programmes is not universal, potentially leading to suboptimal management of poisoned patients. Study objectives – To evaluate baseline diagnostic accuracy and management of poisoning emergencies by undergraduate paramedics and the effect of participation in a targeted toxicological training intervention on diagnostic accuracy and management among undergraduate paramedics when assessed through clinical simulation. Methods – The research utilised a two-stage repeated measures design; following completion of a Likert scale questionnaire a cohort of final year undergraduate paramedics from the University of Northamptonshire undertook three 5-minute simulated patient scenarios on a Laerdal SimMan® programmed to display specific clinical signs; a written sheet with a brief history accompanied each scenario. The scenarios were designed to reflect current paramedic practice comprising opioid (scenario 1), tricyclic antidepressant (scenario 2) and beta blocker overdoses (scenario 3). Two weeks after completing the scenarios the cohort attended a targeted 90-minute educational intervention; a further two months later the cohort repeated the scenarios although the order in which the individual cases were encountered was changed.Peer reviewe

Identification of Cytotoxic Flavor Chemicals in Top-Selling Electronic Cigarette Refill Fluids.

We identified the most popular electronic cigarette (EC) refill fluids using an Internet survey and local and online sales information, quantified their flavor chemicals, and evaluated cytotoxicities of the fluids and flavor chemicals. "Berries/Fruits/Citrus" was the most popular EC refill fluid flavor category. Twenty popular EC refill fluids were purchased from local shops, and the ingredient flavor chemicals were identified and quantified by gas chromatography-mass spectrometry. Total flavor chemical concentrations ranged from 0.6 to 27.9 mg/ml, and in 95% of the fluids, total flavor concentration was greater than nicotine concentration. The 20 most popular refill fluids contained 99 quantifiable flavor chemicals; each refill fluid contained 22 to 47 flavor chemicals, most being esters. Some chemicals were found frequently, and several were present in most products. At a 1% concentration, 80% of the refill fluids were cytotoxic in the MTT assay. Six pure standards of the flavor chemicals found at the highest concentrations in the two most cytotoxic refill fluids were effective in the MTT assay, and ethyl maltol, which was in over 50% of the products, was the most cytotoxic. These data show that the cytotoxicity of some popular refill fluids can be attributed to their high concentrations of flavor chemicals

Neoplasms of the Internal Auditory Canal

Histopathological studies of tumors of the temporal bone are scarce. The authors examined a relatively large number of sectioned human temporal bones in search of small asymptomatic acoustic neurilemmomata and have reported the findings (Leonard and Talbot, 1970). During that search, several other neoplasms were encountered in the internal auditory canal. This report presents a clinical and pathological review of these lesions

High concentrations of flavor chemicals are present in electronic cigarette refill fluids.

We characterized the flavor chemicals in a broad sample of commercially available electronic cigarette (EC) refill fluids that were purchased in four different countries. Flavor chemicals in 277 refill fluids were identified and quantified by gas chromatography-mass spectrometry, and two commonly used flavor chemicals were tested for cytotoxicity with the MTT assay using human lung fibroblasts and epithelial cells. About 85% of the refill fluids had total flavor concentrations >1 mg/ml, and 37% were >10 mg/ml (1% by weight). Of the 155 flavor chemicals identified in the 277 refill fluids, 50 were present at ≥1 mg/ml in at least one sample and 11 were ≥10 mg/ml in 54 of the refill fluids. Sixty-one% (170 out of 277) of the samples contained nicotine, and of these, 56% had a total flavor chemical/nicotine ratio >2. Four chemicals were present in 50% (menthol, triacetin, and cinnamaldehyde) to 80% (ethyl maltol) of the samples. Some products had concentrations of menthol ("Menthol Arctic") and ethyl maltol ("No. 64") that were 30 times (menthol) and 100 times (ethyl maltol) their cytotoxic concentration. One refill fluid contained cinnamaldehyde at ~34% (343 mg/ml), more than 100,000 times its cytotoxic level. High concentrations of some flavor chemicals in EC refill fluids are potentially harmful to users, and continued absence of any regulations regarding flavor chemicals in EC fluids will likely be detrimental to human health

Litter decay rates are determined by lignin chemistry

Litter decay rates are often correlated with the initial lignin:N or lignin:cellulose content of litter, suggesting that interactions between lignin and more labile compounds are important controls over litter decomposition. The chemical composition of lignin may influence these interactions, if lignin physically or chemically protects labile components from microbial attack. We tested the effect of lignin chemical composition on litter decay in the field during a year-long litterbag study using the model system Arabidopsis thaliana. Three Arabidopsis plant types were used, including one with high amounts of guaiacyl-type lignin, one with high aldehyde- and p-hydroxyphenyl-type lignin, and a wild type control with high syringyl-type lignin. The high aldehyde litter lost significantly more mass than the other plant types, due to greater losses of cellulose, hemicellulose, and N. Aldehyde-rich lignins and p-hydroxyphenyl-type lignins have low levels of cross-linking between lignins and polysaccharides, supporting the hypothesis that chemical protection of labile polysaccharides and N is a mechanism by which lignin controls total litter decay rates. 2D NMR of litters showed that lignin losses were associated with the ratio of guaiacyl-to-p-hydroxyphenyl units in lignin, because these units polymerize to form different amounts of labile- and recalcitrant-linkages within the lignin polymer. Different controls over lignin decay and polysaccharide and N decay may explain why lignin:N and lignin:cellulose ratios can be better predictors of decay rates than lignin content alone

Predictions of the dynamic response of piled foundations in a multi-layered half-space due to inertial and railway induced loadings

In this paper, the dynamic pile-soil-pile interaction (PSPI) in a multi-layered half-space is investigated for the prediction of the response of piled foundations due to railway vibrations. Two methods of modelling piled foundations in a multi-layered half-space are presented. The first is an efficient semi-analytical model that calculates the Green’s functions of the multi-layered half-space soil using the thin layer and the dynamic stiffness matrix methods. The second is a fully-coupled model that utilises the boundary element (BE) method to simulate the soil, where the Green’s functions are calculated using the ElastoDynamics Toolbox (EDT). The paper aims to investigate the accuracy and the efficiency of the semi-analytical model by comparing the predictions of the two methods. A set of comparisons is performed, including the driving point response of a single pile and the interaction between two piles. The comparisons reveal that, at most frequencies, the semi-analytical model can predict the driving point response and the dynamic interaction with acceptable accuracy and computational efficiency. The model is then used for predicting the response of a pile-group due to the vibration field generated by a railway in varying distance from the piles. The vibration field generated by the railway is modelled as the superposition of the response due to harmonic loadings generated at the wheel-rail interface and the vibration response is examined at different points on the free surface away from the piles. The comparisons highlight the efficiency and accuracy of the semi-analytical model and illustrate its practical application

Modelling of train-induced vibration

This paper reports on recent developments in techniques for modelling ground vibration from railways. The modelling considers both surface and underground railways, and accounts for the main dynamic systems involved, i.e. tracks (both ballasted and slab), tunnels and multi-layered ground. Results are presented to illustrate the modelling capabilities and the efficiency of computations for the models proposed. The work presented is part of the MOTIV project (Modelling of Train Induced Vibration), which is a collaboration between the Universities of Southampton and Cambridge. Future development of models and plans within the project are also addressed

Economic development, human development, and the pursuit of happiness, April 1, 2, and 3, 2004

This repository item contains a single issue of the Pardee Conference Series, a publication series that began publishing in 2006 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future. This was the Center's spring conference, which took place during April 1, 2, and 3, 2004.The conference asks the questions, how can we make sure that the benefits of economic growth flow into health, education, welfare, and other aspects of human development; and what is the relationship between human development and economic development? Speakers and participants discuss the role that culture, legal and political institutions, the UN Developmental Goals, the level of decision-making, and ethics, play in development