Association between dietary saccharide intake and self-reported memory performance in middle-aged adults

The aims of the present study were to assess dietary intake of saccharides in middle-aged adults, and to determine whether intakes of these sugar nutrients were related to self-reported memory performance. A population-based sample of 1183 men and women (aged 40-60 years) completed questionnaires assessing everyday memory function. Dietary intake status of saccharides was estimated using a self-completed, quantified FFQ. After controlling for demographic and health measures (for example, time spent exercising, smoking and alcohol consumption), saccharide intake was related to better self-reported memory functioning. Thus, longer-term intakes of saccharides through the usual diet may be positively related to perceived memory performance in mid-life

Saccharide Effects on Cognition and Well-Being in Middle-Aged Adults: A Randomized Controlled Trial

Author version made available in accordance with the publisher's policy.The current study used a randomised, double-blind, placebo-controlled design to investigate the effects of saccharide supplementation on cognition and well-being in middle-aged adults. Participants (N=109; 45 - 60 years) took a teaspoon of a combination of saccharides or a placebo twice daily for 12 weeks (3.6 g per day). Before and after this supplementation period, participants completed alternate forms of standardised tests of cognition and self-report measures of well-being. Significant beneficial effects of saccharide supplementation were found for memory performance and indicators of well-being. The potential for these nutrients to optimise cognitive function and well-being in older adults warrants on-going investigation

Perceived Changes in Well-Being Following Polysaccharide Intake in Middle-Aged Adults

Author version made available in accordance with the publisher's policy.Objectives: There is increased scientific interest in the effects of nutrition on cognition and well-being. Plant sourced polysaccharides play multiple roles in the biological processes required for health and well-being. This study explored the subjective experiential reports of well-being following intake of a plant derived polysaccharide supplement. Design: The study used a 12 week double-blind, placebo controlled polysaccharide supplementation design. Method: 109 middle-aged adults (45-60 years) took a standardised teaspoon of a combination of plant polysaccharides or a placebo twice daily for 12 weeks (3.6 g per day), and completed three, open-ended interviews at weeks 4, 8 and 12. Results: Participants who took the polysaccharide supplement reported significantly more perceived beneficial changes in both physical and psychological well-being, specifically at week 12, compared to those who received the placebo. Conclusion: This study provides a starting point for understanding the perceived beneficial impact of polysaccharide interventions on aspects of well-being. Importantly, as a healthrelated application of polysaccharide science, this research supports the relationship that is emerging between the properties and function of polysaccharides. It is essential that future research assesses the effects of polysaccharide intake on a range of physical and psychological well-being outcomes to further the understanding of structure-function relationships with the aim of enhancing the functional health and well-being of individuals

Character Dialogue and How It Works in Cinema

BEYOND THE DOOR is a psychological thriller screenplay about an abandoned house and two sixth-grade girls with a shared trauma

How important is ‘implementation science’ for national genomics policy?

The traditional translation pathway of ‘bench- to-bedside’ will not be enough to integrate genomics into routine clinical care. It requires the use of validated and systematic ‘implementation science’ methods. Within the pipeline of evidence-based translation of new technologies, implementation science is the phase that informs policy regarding the appropriateness, adoption, feasibility, acceptability, fidelity, penetration, and sustainability of technologies being transferred from research settings into the real world. Without implementation science, barriers can emerge unchecked and key drivers neglected. Health services researchers now have a large knowledge base which identifies barriers and drivers for implementation of new technologies into healthcare

Mathematical Models: Interactions Between Serotonin and Dopamine in Parkinson’s Disease

Non

The response of young adult smokers and nonsmokers in the United Kingdom to dissuasive cigarettes: An online survey

Introduction  The cigarette stick is an important communications tool as well as the object of consumption. We explored young adults’ responses to cigarettes designed to be dissuasive.  Methods  Data come from a cross-sectional online survey, conducted in September 2015, with 16-24 year old smokers and non-smokers (N=997) in the United Kingdom. Participants were shown images of a standard cigarette (white cigarette paper with imitation cork filter), a standard cigarette displaying the warning ‘Smoking kills’ on the cigarette paper, and an unattractively coloured cigarette (green cigarette paper and filter). They were asked to rate each of the three cigarettes, shown individually, on eight perception items, and to rate the three cigarettes, shown together, on how likely they would be to try them. Ordering of the cigarettes and questions, with the exception of the question on trial, was randomised.  Results  The eight perceptions items were combined to form a composite measure of cigarette perceptions. For smokers and non-smokers, the two dissuasive cigarettes (cigarette with warning, green cigarette) were rated significantly less favourably than the standard cigarette, and less likely to encourage trial. For cigarette perceptions no significant interaction was detected between cigarette style and smoking status or susceptibility to smoke among never smokers. A significant interaction was found for likelihood of trying the cigarettes, with dissuasive cigarettes having a greater impact with smokers than non-smokers.  Conclusions  This study suggests that dissuasive cigarettes may help to reduce the desirability of cigarettes.  Implications The cigarette stick is the object of tobacco consumption, which is seen every time a cigarette is smoked. It is also an increasingly important promotional tool for tobacco companies. In this study, young adults rated two dissuasive cigarettes (a green coloured cigarette and a cigarette displaying a health warning) more negatively than a standard cigarette, and considered them less likely to encourage product trial. Our findings suggest that it may be possible to reduce the desirability of cigarette sticks by altering their design, e.g. with the addition of a warning or use of an unattractive colour

Developing a research strategy to better understand, observe, and simulate urban atmospheric processes at kilometer to subkilometer scales

A Met Office/Natural Environment Research Council Joint Weather and Climate Research Programme workshop brought together 50 key international scientists from the UK and international community to formulate the key requirements for an Urban Meteorological Research strategy. The workshop was jointly organised by University of Reading and the Met Office

Homeostasis Patterns

Homeostasis is a regulatory mechanism that keeps a specific variable close to a set value as other variables fluctuate. The notion of homeostasis can be rigorously formulated when the model of interest is represented as an input-output network, with distinguished input and output nodes, and the dynamics of the network determines the corresponding input-output function of the system. In this context, homeostasis can be defined as an 'infinitesimal' notion, namely, the derivative of the input-output function is zero at an isolated point. Combining this approach with graph-theoretic ideas from combinatorial matrix theory provides a systematic framework for calculating homeostasis points in models and classifying the different homeostasis types in input-output networks. In this paper we extend this theory by introducing the notion of a homeostasis pattern, defined as a set of nodes, in addition to the output node, that are simultaneously infinitesimally homeostatic. We prove that each homeostasis type leads to a distinct homeostasis pattern. Moreover, we describe all homeostasis patterns supported by a given input-output network in terms of a combinatorial structure associated to the input-output network. We call this structure the homeostasis pattern network.Comment: 33 pages, 7 figures, 2 table