27 research outputs found

    Evaluasi Sistem Informasi Penjualan PT SPNS

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    The purpose of this paper is to identify and analyze problems that occur in information systems sales PT SPNS. It also serves to control the management and control of applications running well so it can produce accurate information for decision making. The method used is book study method and field study. Study was done by reading library books, scientific papers and other sources, while the field study was done by observation, interviews, and questionnaires. The result of the evaluation is derived from the respective strengths and weaknesses - each control. Weaknesses are found, the findings presented in the form of a matrix that contains the findings and recommendations as a matter of risk remedial action. Conclusions obtained from the audit for security control, operations, limitations, input and output is good enough because it can satisfy and support the sales activities of PT SPNS

    Technical aspects and clinical limitations of sperm DNA fragmentation testing in male infertility: a global survey, current guidelines, and expert recommendations.

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    PURPOSE: Sperm DNA fragmentation (SDF) is a functional sperm abnormality that can impact reproductive potential, for which four assays have been described in the recently published sixth edition of the WHO laboratory manual for the examination and processing of human semen. The purpose of this study was to examine the global practices related to the use of SDF assays and investigate the barriers and limitations that clinicians face in incorporating these tests into their practice. MATERIALS AND METHODS: Clinicians managing male infertility were invited to complete an online survey on practices related to SDF diagnostic and treatment approaches. Their responses related to the technical aspects of SDF testing, current professional society guidelines, and the literature were used to generate expert recommendations via the Delphi method. Finally, challenges related to SDF that the clinicians encounter in their daily practice were captured. RESULTS: The survey was completed by 436 reproductive clinicians. Overall, terminal deoxynucleotidyl transferase deoxyuridine triphosphate Nick-End Labeling (TUNEL) is the most commonly used assay chosen by 28.6%, followed by the sperm chromatin structure assay (24.1%), and the sperm chromatin dispersion (19.1%). The choice of the assay was largely influenced by availability (70% of respondents). A threshold of 30% was the most selected cut-off value for elevated SDF by 33.7% of clinicians. Of respondents, 53.6% recommend SDF testing after 3 to 5 days of abstinence. Although 75.3% believe SDF testing can provide an explanation for many unknown causes of infertility, the main limiting factors selected by respondents are a lack of professional society guideline recommendations (62.7%) and an absence of globally accepted references for SDF interpretation (50.3%). CONCLUSIONS: This study represents the largest global survey on the technical aspects of SDF testing as well as the barriers encountered by clinicians. Unified global recommendations regarding clinician implementation and standard laboratory interpretation of SDF testing are crucial

    Controversy and consensus on the management of elevated sperm DNA fragmentation in male infertility: a global survey, current guidelines, and expert recommendations

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    PURPOSE: Sperm DNA fragmentation (SDF) has been associated with male infertility and poor outcomes of assisted reproductive technology (ART). The purpose of this study was to investigate global practices related to the management of elevated SDF in infertile men, summarize the relevant professional society recommendations, and provide expert recommendations for managing this condition. MATERIALS AND METHODS: An online global survey on clinical practices related to SDF was disseminated to reproductive clinicians, according to the CHERRIES checklist criteria. Management protocols for various conditions associated with SDF were captured and compared to the relevant recommendations in professional society guidelines and the appropriate available evidence. Expert recommendations and consensus on the management of infertile men with elevated SDF were then formulated and adapted using the Delphi method. RESULTS: A total of 436 experts from 55 different countries submitted responses. As an initial approach, 79.1% of reproductive experts recommend lifestyle modifications for infertile men with elevated SDF, and 76.9% prescribe empiric antioxidants. Regarding antioxidant duration, 39.3% recommend 4-6 months and 38.1% recommend 3 months. For men with unexplained or idiopathic infertility, and couples experiencing recurrent miscarriages associated with elevated SDF, most respondents refer to ART 6 months after failure of conservative and empiric medical management. Infertile men with clinical varicocele, normal conventional semen parameters, and elevated SDF are offered varicocele repair immediately after diagnosis by 31.4%, and after failure of antioxidants and conservative measures by 40.9%. Sperm selection techniques and testicular sperm extraction are also management options for couples undergoing ART. For most questions, heterogenous practices were demonstrated. CONCLUSIONS: This paper presents the results of a large global survey on the management of infertile men with elevated SDF and reveals a lack of consensus among clinicians. Furthermore, it demonstrates the scarcity of professional society guidelines in this regard and attempts to highlight the relevant evidence. Expert recommendations are proposed to help guide clinicians

    Pengaruh Bauran Pemasaran Terhadap Keputusan Pembelian Sepeda Motor Merk Honda di PT. Nusantara Surya Sakti Pontianak

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    Purpose of this study was to determine the effect of the marketing mix on purchase decisions of Honda motorcycles in PT Nusantara Surya Sakti Pontianak. The study is a descriptive study, using data collected through observation, interviews, questionnaires, and corporate documents. The population of consumers who purchased a motorcycle brands Honda PT. NSS Pontianak and the sample is determined as much as 97 respondents. Terms samples are age (20-56) old, Buying motorcycle brands Honda for its own purposes, able to read and write well, Domiciled in Pontianak City and surrounding areas. The analytical tool used is a simple regression. The results showed that the constant value obtained was 0.079, meaning that if the elements of the marketing mix is 0 (zero), then the consumer purchase decisions of Honda motorcycles brands in PT Nusantara Surya Sakti would be worth 0.079. Simple regression coefficient value of the marketing mix variables obtained at 0.964, meaning that if the marketing mix is increased by one unit, then the purchasing decisions of consumers on the purchase of Honda's motorcycle brands in PT. Nusantara Surya Sakti Pontianak will increase by 0.964 units.</jats:p

    Photochemical screening and corrosion inhibition of Poupartia birrea back extracts as a potential green inhibitor for mild steel in 0.5 M H2SO4 medium

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    Corrosion of metals is a serious environmental problem and has been given much attention in the oil and gas industries. In several industrial processes (acid cleaning and etching, removal of rust and scale), metal surfaces are often made to come in contact with acids. In the present study, an attempt was made to examine Poupartia birrea (P. birres) back extract as a potential green corrosion inhibitor for mild steel in a 0.5 M H2SO4 medium, using the weight loss determination method. The results of our work indicate that highest inhibition efficiency exhibited by Poupartia birrea is 70%. The inhibiting effect of the studied extract could be attributed to the presence of phytochemical constituents present in the extract that are adsorbed on the surface of the mild steel. The plant extract can, hence, be considered as being eco-friendly and an effective green corrosion inhibitor for mild steel exposed to an acid medium

    Preparation of slow-release fertilizer derived from rice husk silica, hydroxypropyl methylcellulose, polyvinyl alcohol and paper composite coated urea

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    There is a growing trend toward utilizing agricultural waste to create value-added products, addressing environmental concerns associated with their disposal. This study focuses on developing slow-release fertilizers (SRFs) using amorphous silica derived from rice husk, hydroxypropyl methylcellulose (HPMC), polyvinyl alcohol (PVA), waste paper, and urea. Experimental optimization was carried out using the response surface methodology central composite design (RSM-CCD). The optimal formulation included 8.63 g of silica, 1.04 g of HPMC, and 0.27 g of PVA. Two SRFs were prepared under these conditions: SRF1, consisting of silica, HPMC, and PVA, and SRF2, which additionally incorporated coated waste paper. Characterization techniques such as Fourier Transform Infrared (FTIR) spectroscopy, X-ray diffraction (XRD) Scanning Electron microscopy (SEM) and Brunauer-Emmett-Teller (BET) analysis were used to examine the materials. The rice-husk-derived silica exhibited a pore size of 2.140 nm and a BET surface area of 690 m2/g, providing an excellent surface for nutrient encapsulation. Although the addition of coated waste paper minimally influenced the slow-release behaviour of SRF2, however the other components effectively reduced nutrient leakage by trapping the nutrients. The swelling behaviour of the SRFs was analyzed in different media after 72 h, showing values of 2.66, 2.54 (g/g) in distilled water, 2.20, 2.58 (g/g) in pH 4, and 1.86, 3.09 (g/g) in pH 9 solutions. The swelling kinetics aligned with Scott's second-order kinetic model. Urea release tests in water revealed a release of 94 % and 97 % at 24 h for SRF1 and SRF2, respectively, compared to 98 % release of pure urea within 1 h. SRF2 demonstrated optimal nutrient release after 48 h. The release kinetics followed the first-order kinetic model for both SRF1 and SRF2, highlighting their potential as effective slow-release fertilizers
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