The Terrestrial Isopod \u3ci\u3eHyloniscus Riparius\u3c/i\u3e (Isopoda: Oniscidea: Trichoniscidae) in Wisconsin

We examined seasonal reproductive patterns for the terrestrial isopod Hyloniscus riparius in Wisconsin. Samples collected from habitats in three Wisconsin regions were compared with regard to the reproductive status of population members. We also recorded differences in sex ratio and stage of female gravidity in all samples. Males were a minority in all samples. Southern samples showed the greatest reproductive capacity based on the proportion of females that were found to be gravid

Terrestrial Isopods (Isopoda: Oniscidea) of Wisconsin

Eleven species of terrestrial isopods are recorded from Wisconsin. Species treatments include morphological, habitat and life history data. Wisconsin county distribution records are presented

Immigrant health: Selectivity and acculturation

There is renewed concern that in spite of overall improvements in health racial and ethnic disparities in health persist and in some cases may even have expanded. Ethnic health disparities are inherently linked to immigration since ethnic identities are traced to the country of origin of an immigrant or his ancestors. The average healthiness of the original immigrants, the diversity in health status among immigrants, the subsequent health trajectories following immigration both over immigrants lifetime and that of their descendents all combine to produce the ethnic health disparities we observe at any point in time. Identifying the determinants of the original health selection of migrants and the forces that shape health paths following immigration is critical to understanding ethnic health differences

Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancer

The purpose of this study was to determine whether staining intensity in conjunction with the percentage of positive tumor cells should be used as an indicator of protein expression detected by immunohistochemistry. A tissue microarray of 1,197 colorectal cancers was immunostained for p53, Her2/neu, epidermal growth factor receptor (EGFR), adenomatosis polyposis coli (APC), and β-catenin. Immunoreactivity was described by the percentage of positive tumor cells (percent positivity) and by the staining intensity (weak, moderate, strong). The interobserver reproducibility of both was evaluated by two pathologists. The association of T stage, N stage, tumor grade, vascular invasion, and survival with percent positivity, staining intensity, and the combination of both was assessed. In univariate analysis, protein expression assessed by percent positivity resulted in 11 significant associations between the proteins and clinico-pathological features. Eight of these 11 were also demonstrated using only the degree of staining intensity. However, more than half of the associations identified by percent positivity alone were lost when staining intensity was also analyzed in combination with the percentage of positive tumor cells. A scoring method based on percent positivity, rather than on staining intensity, for p53, Her2/neu, EGFR, APC, and β-catenin is reproducible and appears to be sufficient for establishing associations of the selected tumor markers with most clinico-pathological feature

DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy

Colorectal cancers (CRC) are thought to have genetic instability in the form of either microsatellite instability (MSI) or chromosomal instability (CIN). Recently, tumours have been described without either MSI or CIN, that is, microsatellite and chromosome stable (MACS) CRCs. We investigated the (i) frequency of the MACS-CRCs and (ii) whether this genotype predicted responsiveness to neoadjuvant chemoradiotherapy. To examine the frequency of MACS-CRCs, DNA content (ploidy) was examined in 89 sporadic microsatellite-stable CRCs using flow cytometry. The tumours were also screened for mutations in KRAS/BRAF/TP53/PIK3CA by QMCPCR. To examine the value of tumour ploidy in predicting response to chemoradiotherapy, DNA content was tested in a separate group of 62 rectal cancers treated with neoadjuvant chemoradiotherapy. Fifty-one of 89 CRCs (57%) were aneuploid and 38 (43%) were diploid. There was no significant association between mutations in TP53/KRAS/BRAF/PIK3CA and ploidy. Testing of association between mutations revealed only mutual exclusivity of KRAS/BRAF mutation (P < 0.001). Of the 62 rectal cancers treated with neoadjuvant chemoradiotherapy, 22 had responded (Mandard tumour regression grade 1/2) and 40 failed to respond (Grade 3–5). Twenty-five of 62 (40%) tumours were diploid, but there was no association between ploidy and response to therapy. We conclude that MACS-CRCs form a significant proportion of microsatellite-stable CRCs with a mutation profile overlapping that of CRCs with CIN. A diploid genotype does not, however, predict the responsiveness to radiotherapy

Dogs just wanna have fun – at the beach

An excerpt from a book by Jass Richards

In the fitness room

In the Fitness Room is excerpted from The Blasphemy Tour. Dylan and Rev have checked into their room at the Curada Hotel. They\u27ve also finished their special cheesecake. All of it

Early Childhood Education Students Give Drama Workshops to Nursery Children

Poster with details of DIT students\u27 workshop with nursery school children. 1st and 2nd year Early Childhood Education students prepare and facilitate drama classes in St Brigid’s Day Nursery local to the College as part of their Drama Education course. The nursery children range in ages of two to four years and are grouped into small groups of 6 to 9 children in each group. The sessions last for 30-50 minutes and for the duration of the drama education class teachers hand over completely to the students.https://arrow.tudublin.ie/civpostbk/1037/thumbnail.jp

Iklim Organisasi dan Komitmen Terhadap Program Mesra Polis Diraja Malaysia : Satu Kajian di Ibu Pejabat Polis Daerah Ampang Jaya Selangor

The Royal Malaysian Police has launched the service friendly program among it members to improve their organizational image. This program is carried out with the members of the Royal Malaysian Police to uphold a high level of commitment in achieving intended objectives. This study is aimed to see the relationship between the perception climate of the organization and the commitment in making the service friendly program a success among the police personals at the enquiry office in various police stations in Ampang Jaya, Selangor Police District. The result of the study shows that many respondents have a high level of knowledge about service friendly program. Where as, the commitment of the respondents towards the program are only at a satisfactory level. The relationship between perceptions of organizational climate and the program commitment from the climatic dimension of the organizational does not show a strong relationship. This is due to the culture in Royal Malaysian Police which exercise a strong discipline and orders from the superior and the rules of the force. Thus, the researcher propose that Royal Malaysian Police should conduct their internal study to find out which internal factor that can improve more the level of commitment among the members of the organization. As such all policies of the Royal Malaysian Police that will be implemented can bring in a positive culture which is more permanent in nature and therefore help the organization to achieve its goals