The small-scale manufacture of compound animal feed (ODNRI Bulletin No. 9)

This bulletin supersedes TDRI report G67 The small-scale manufacture of compound animal feed, which was first published in 1971. lt retains a similar format to G67, but the text has been extensively revised and expanded in the light of numerous enquiries dealt with by ODNRI on all aspects of feed production in the intervening years. lt is hoped that it will act as a technical and investment guide for those interested in initiating the production of compound animal feeds, as well as acting as a useful reference report for those already actively operating in this field. Chapter 1 describes the economic background to the industry; theoretical aspects of animal nutrition are dealt with in Chapter 2; these are related to the properties of the various raw materials used in feed production in Chapter 3. Chapter 4 describes the manufacturing process and examines the physical requirements for setting up plants at various scales of output, and Chapter 5 develops cost and return models for the plants described

Re Bakery and Confectionery Workers\u27 International Union, Local 322, and Canada Bread Co Ltd

Union Grievance alleging violation of a supplementary agreement concerning shift rotation. The Facts: With the implementation of the collective agreement of 1968, which preceded the present agreement, the company introduced in the shipping department a system which involved some rotation of shifts. That system is no longer in effect, and there is some uncertainty just when it ceased. It is agreed, however, that early in 1970 the company lost a major customer. That customer was last served on Saturday, February 28th, and a substantial lay-off followed immediately. On Sun-day, March 8th, the company\u27s employees went on a legal strike, and returned to work on April 5th. Probably since February 28th, and certainly since the strike, the company has not operated a system of shift rotation

Attachment re'story'ation through Playback Theatre : construction of a program guide for mothers with insecure attachment narratives

This program guide is constructed based on a review of attachment theory, the reflective function, adult attachment narratives, and Playback theatre. Integrating Playback theatre, drama therapeutic exercises, and relevant theory related to attachment work, this original program guide serves to benefit mothers who have been indicated as having insecure attachment narratives by the Adult Attachment Interview (AAI). The 20-week, five-stage program intends to promote the reconstruction of attachment narratives, increase empathy and the reflective function, and facilitate insight into attachment experiences. Reflective functioning, a concept that has been shown to be fundamental in the attachment process, and empathy are promoted in the program by integrating the mothers in the Playback theatre process as actors. The group therapy structure also serves to promote secure attachment relationships and change the perceptions and expectations of personal relationships. Playback theatre is an effective modality for mothers with insecure attachment narratives as it facilitates an exploration of personal stories. Playback theatre offers a non-judgmental and respectful forum where stories are given a chance to be told, witnessed, and transformed in an aesthetic and powerful way. From member referrals to program evaluation, the program guide outlines necessary elements and steps needed to implement the program in a variety of settings

Novel Roles of SOCS3 as a Tumour Suppressor

Cancer is a collection of diseases that were responsible for approximately ten million deaths in 2020. Colorectal cancer (CRC) is the third most common type of cancer; it occurs following the transformation of normal epithelial cells to adenocarcinoma which can eventually result in metastasis. Treatments are continuously being researched and developed, with immunotherapy becoming an increasingly common area of research against cancer. The enzyme indoleamine 2,3-dioxygenase (IDO) has been identified as a cause of tumour immune tolerance through the creation of a tryptophan-starved state in cells. Hence, blockers to IDO have been studied to test their efficacy in treating cancers. IDO blocker Epacadostat has been found to be effective in mice but has proven to be variable in success in human trials. Another IDO blocker under investigation is 1-methyl-D-tryptophan (1-MT). This project aimed to investigate the impact of the loss of tumour suppressor, SOCS3, on 1-MT treatment due to its ability to regulate IDO expression. SOCS3 silencing has been associated with some human cancers, therefore this study used conditional intestinal epithelial SOCS3 knockout mice (IECS3-/-) to recapitulate the loss of SOCS3 in intestinal adenocarcinoma. An azoxymethane/ dextran sodium sulphate (AOM/DSS) model was used to induce colon cancer and conditional knockout, or wild-type mice were administered either 1-MT or water. Analysis of the intestinal macrophages was performed using immunohistochemistry, IDO activity assessed using HPLC, and cell culture techniques to investigate impact of 1-MT in vitro. A decrease in M1 pro-inflammatory macrophages was found in the colon of IECS3 -/- 1-MT treated mice, and an increase in CD206+ IBA1- cells (potential immature dendritic cells (IDCs)) in IECS3-/- H2O treated mice. These findings indicate that a SOCS3 deficiency may play a role in reducing the efficacy of 1-MT immunotherapy treatment, presenting itself as a potential biomarker that could help identify patients who are likely to see improved prognosis following IDO-inhibitor treatment

Beliefs About Medication and Uptake of Preventive Therapy in Women at Increased Risk of Breast Cancer: Results From a Multicenter Prospective Study

Introduction Uptake of preventive therapies for breast cancer is low. We examined whether women at increased risk of breast cancer can be categorized into groups with similar medication beliefs, and whether belief group membership was prospectively associated with uptake of preventive therapy. Patients and Methods Women (n = 732) attending an appointment to discuss breast cancer risk were approached; 408 (55.7%) completed the Beliefs About Medicines and the Perceived Sensitivity to Medicines questionnaires. Uptake of tamoxifen at 3 months was reported in 258 (63.2%). The optimal number of belief groups were identified using latent profile analysis. Results Uptake of tamoxifen was 14.7% (38/258). One in 5 women (19.4%; 78/402) reported a strong need for tamoxifen. The model fit statistics supported a 2-group model. Both groups held weak beliefs about their need for tamoxifen for current and future health. Group 2 (38%; 154/406 of the sample) reported stronger concerns about tamoxifen and medicines in general, and stronger perceived sensitivity to the negative effects of medicines compared with group 1 (62%; 252/406). Women with low necessity and lower concerns (group 1) were more likely to initiate tamoxifen (18.3%; 33/180) than those with low necessity and higher concerns (group 2) (6.4%; 5/78). After adjusting for demographic and clinical factors, the odds ratio was 3.37 (95% confidence interval, 1.08-10.51; P = .036). Conclusion Uptake of breast cancer preventive therapy was low. A subgroup of women reported low need for preventive therapy and strong medication concerns. These women were less likely to initiate tamoxifen. Medication beliefs are targets for supporting informed decision-making

PREVALENCE OF PARASITES WITH ZOONOTIC POTENTIAL IN SOIL FROM THE MAIN PUBLIC PARKS AND SQUARES IN CAXIAS DO SUL, RS, BRAZIL

Soil contamination in parks and public squares caused by animal feces has been one of the main forms of parasitic contamination, becoming therefore a public health problem. The purpose of this study was to determine the prevalence of parasites in the soil in major parks and public squares in Caxias do Sul, RS, Brazil. Two samplings were performed at each location, the firstin summer (February) and the second in winter (July) in 2015. Soil samples were collected in five spots in ten parks/public squares, per season and examined using the Hoffman, Pons & Janer (HPJ), Faust and Rugai, Mattos and Brisola methods. Among the 100 samples analyzed by HPJ and Rugai, Mattos and Brisola, 64% and 58% respectively, proved positive in summerand 28% and 60% in winter. The Faust method showed the same number of positive samples in both seasons (12% each). The following parasites were found: Cystosospora sp oocysts (4%), Entamoeba coli cysts (1%), Strongyloides stercoralis suggestive larvae (0.3%), Endolimax nanacysts (1%) and Ancylostoma sp suggestive larvae (33.3%) with the highest prevalence. Both parks and squares presented parasites with zoonotic potential. Thus, it is necessary to highlight the importance of educational measures regarding the use of these locations as well as the cleaning of public areas with the removal of animal excrements

The COVID-19 Crisis: Using the Cracks in Neoliberalism for Social Transformation Towards a More Just Society

Within the current COVID-19 pandemic, cracks observed in neoliberal dominant global economic paradigms reveal how austerity policies have crippled crucial social safety nets, such as health care, with capitalism continuing to adversely impact our climate with ad infinitum extraction of resources for overconsumption. In examining these associations, this collaborative paper critically applies social theories to explore ideas and approaches to creating transformative social change, in an effort to move towards a more just and sustainable society in the context of the COVID-19 pandemic and other ongoing systemic crises. The paper presents the pandemic as a social crisis and explores theories of social justice and how they might be applied within the context of neoliberal capitalism, also known as neoliberalism. The authors of this paper argue that to move towards a just society, social transformation is needed, informed by the theories of decoloniality and intersectionality. A conceptual model is presented that demonstrates how these theories can be woven together to inform community psychology action and research, addressing COVID-19 specifically. Possibilities for transformation in the areas of mental health and climate justice are also presented. Finally, recommendations for community psychology researchers seeking social transformation, while navigating this challenging and complex new reality, are shared

The COVID-19 Crisis: Using the Cracks in Neoliberalism for Social Transformation Towards a More Just Society

Within the current COVID-19 pandemic, cracks observed in neoliberal dominant global economic paradigms reveal how austerity policies have crippled crucial social safety nets, such as health care, with capitalism continuing to adversely impact our climate with ad infinitum extraction of resources for overconsumption. In examining these associations, this collaborative paper critically applies social theories to explore ideas and approaches to creating transformative social change, in an effort to move towards a more just and sustainable society in the context of the COVID-19 pandemic and other ongoing systemic crises. The paper presents the pandemic as a social crisis and explores theories of social justice and how they might be applied within the context of neoliberal capitalism, also known as neoliberalism. The authors of this paper argue that to move towards a just society, social transformation is needed, informed by the theories of decoloniality and intersectionality. A conceptual model is presented that demonstrates how these theories can be woven together to inform community psychology action and research, addressing COVID-19 specifically. Possibilities for transformation in the areas of mental health and climate justice are also presented. Finally, recommendations for community psychology researchers seeking social transformation, while navigating this challenging and complex new reality, are shared