8,130 research outputs found
Dual-wavelength ultra-short pulse generation by use of semiconductor laser diode
2002-2003 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
A compact statistical model of the song syntax in Bengalese finch
Songs of many songbird species consist of variable sequences of a finite
number of syllables. A common approach for characterizing the syntax of these
complex syllable sequences is to use transition probabilities between the
syllables. This is equivalent to the Markov model, in which each syllable is
associated with one state, and the transition probabilities between the states
do not depend on the state transition history. Here we analyze the song syntax
in a Bengalese finch. We show that the Markov model fails to capture the
statistical properties of the syllable sequences. Instead, a state transition
model that accurately describes the statistics of the syllable sequences
includes adaptation of the self-transition probabilities when states are
repeatedly revisited, and allows associations of more than one state to the
same syllable. Such a model does not increase the model complexity
significantly. Mathematically, the model is a partially observable Markov model
with adaptation (POMMA). The success of the POMMA supports the branching chain
network hypothesis of how syntax is controlled within the premotor song nucleus
HVC, and suggests that adaptation and many-to-one mapping from neural
substrates to syllables are important features of the neural control of complex
song syntax
FIH-1, a novel interactor of mindbomb, functions as an essential anti-angiogenic factor during zebrafish vascular development
Objective: It has been shown that Mindbomb (Mib), an E3 Ubiquitin ligase, is an essential modulator of Notch signaling during development. However, its effects on vascular development remain largely unknown
HIV prevalence and undiagnosed infection among a community sample of gay and bisexual men in Scotland, 2005-2011: implications for HIV testing policy and prevention
<b>Objective</b><p></p>
To examine HIV prevalence, HIV testing behaviour, undiagnosed infection and risk factors for HIV positivity among a community sample of gay men in Scotland.<p></p>
<b>Methods</b><p></p>
Cross-sectional survey of gay and bisexual men attending commercial gay venues in Glasgow and Edinburgh, Scotland with voluntary anonymous HIV testing of oral fluid samples in 2011. A response rate of 65.2% was achieved (1515 participants).<p></p>
<b>Results</b><p></p>
HIV prevalence (4.8%, 95% confidence interval, CI 3.8% to 6.2%) remained stable compared to previous survey years (2005 and 2008) and the proportion of undiagnosed infection among HIV-positive men (25.4%) remained similar to that recorded in 2008. Half of the participants who provided an oral fluid sample stated that they had had an HIV test in the previous 12 months; this proportion is significantly higher when compared to previous study years (50.7% versus 33.8% in 2005, p<0.001). Older age (>25 years) was associated with HIV positivity (1.8% in those <25 versus 6.4% in older ages group) as was a sexually transmitted infection (STI) diagnosis within the previous 12 months (adjusted odds ratio 2.13, 95% CI 1.09–4.14). There was no significant association between age and having an STI or age and any of the sexual behaviours recorded.<p></p>
<b>Conclusion</b><p></p>
HIV transmission continues to occur among gay and bisexual men in Scotland. Despite evidence of recent testing within the previous six months, suggesting a willingness to test, the current opt-out policy may have reached its limit with regards to maximising HIV test uptake. Novel strategies are required to improve regular testing opportunities and more frequent testing as there are implications for the use of other biomedical HIV interventions.<p></p>
Transmit Power Minimization for MIMO Systems of Exponential Average BER with Fixed Outage Probability
This document is the Accepted Manuscript version of the following article: Dian-Wu Yue, and Yichuang Sun, ‘Transmit Power Minimization for MIMO Systems of Exponential Average BER with Fixed Outage Probability’, Wireless Personal Communications, Vol. 90 (4): 1951-1970, first available online on 20 June 2016. Under embargo. Embargo end date: 20 June 2017. The final publication is available at Springer via https://link.springer.com/article/10.1007%2Fs11277-016-3432-4This paper is concerned with a wireless multiple-antenna system operating in multiple-input multiple-output (MIMO) fading channels with channel state information being known at both transmitter and receiver. By spatiotemporal subchannel selection and power control, it aims to minimize the average transmit power (ATP) of the MIMO system while achieving an exponential type of average bit error rate (BER) for each data stream. Under the constraints on each subchannel that individual outage probability and average BER are given, based on a traditional upper bound and a dynamic upper bound of Q function, two closed-form ATP expressions are derived, respectively, which can result in two different power allocation schemes. Numerical results are provided to validate the theoretical analysis, and show that the power allocation scheme with the dynamic upper bound can achieve more power savings than the one with the traditional upper bound.Peer reviewe
A SM-like Higgs near 125 GeV in low energy SUSY: a comparative study for MSSM and NMSSM
Motivated by the recent LHC hints of a Higgs boson around 125 GeV, we assume
a SM-like Higgs with the mass 123-127 GeV and study its implication in low
energy SUSY by comparing the MSSM and NMSSM. We consider various experimental
constraints at 2-sigma level (including the muon g-2 and the dark matter relic
density) and perform a comprehensive scan over the parameter space of each
model. Then in the parameter space which is allowed by current experimental
constraints and also predicts a SM-like Higgs in 123-127 GeV, we examine the
properties of the sensitive parameters (like the top squark mass and the
trilinear coupling A_t) and calculate the rates of the di-photon signal and the
VV^* (V=W,Z) signals at the LHC. Our typical findings are: (i) In the MSSM the
top squark and A_t must be large and thus incur some fine-tuning, which can be
much ameliorated in the NMSSM; (ii) In the MSSM a light stau is needed to
enhance the di-photon rate of the SM-like Higgs to exceed its SM prediction,
while in the NMSSM the di-photon rate can be readily enhanced in several ways;
(iii) In the MSSM the signal rates of pp -> h -> VV^* at the LHC are never
enhanced compared with their SM predictions, while in the NMSSM they may get
enhanced significantly; (iv) A large part of the parameter space so far
survived will be soon covered by the expected XENON100(2012) sensitivity
(especially for the NMSSM).Comment: Version in JHEP (refs added
Emergence of non-centrosymmetric topological insulating phase in BiTeI under pressure
The spin-orbit interaction affects the electronic structure of solids in
various ways. Topological insulators are one example where the spin-orbit
interaction leads the bulk bands to have a non-trivial topology, observable as
gapless surface or edge states. Another example is the Rashba effect, which
lifts the electron-spin degeneracy as a consequence of spin-orbit interaction
under broken inversion symmetry. It is of particular importance to know how
these two effects, i.e. the non-trivial topology of electronic states and
Rashba spin splitting, interplay with each other. Here we show, through
sophisticated first-principles calculations, that BiTeI, a giant bulk Rashba
semiconductor, turns into a topological insulator under a reasonable pressure.
This material is shown to exhibit several unique features such as, a highly
pressure-tunable giant Rashba spin splitting, an unusual pressure-induced
quantum phase transition, and more importantly the formation of strikingly
different Dirac surface states at opposite sides of the material.Comment: 5 figures are include
Behind China’s English Fever: The Contested Discourses on English Education and People’s Yearning for Flexible Citizenship
I propose a study on China’s English Fever under the interdisciplinary framework of cultural studies. Having taught English at the university level in China, I have had the opportunity not only to witness such a English-learning phenomenon that has been sweeping the country for about three decades, but also to teach students who are incredibly enthusiastic in learning English, regardless of their majors and of their initially drastically different English proficiency levels. What always intrigues me is the question of why: Why are Chinese people so dedicated to learning English? The proposed study is an attempt to look for some plausible answers to this central question from two related yet separate, not always aligned perspectives: the perspective of the government and that of the common people.
Situating China’s English fever under the broad and discursive framework of cultural studies, I will mainly draw on poststructuralism and Derridean deconstruction. The proposed study will begin with a review of the development of English language education in China, tracing back the history of how English replaced Russia in the late 1970s in the national school curriculum. The second part of the study will explore the Chinese government’s two contested discourses on English education—“English for everyone” vs. “English not important”—via analyzing the news and editorials from China’s most authoritative media outlets, such as China Daily and Xinhua News Agency. The third part will investigate Chinese people’s continuing obsession with English despite the government’s recurring backlashes against English by analyzing people’s discussion about reasons of learning English on major Chinese social media, such Baidu Tieba and Douban.
My major augments/findings are: 1) China’s English fever is much more than an urge to master a global language; instead it is driven both by the government’s pro-English language education policy and by people’s yearning for mobility and flexible citizenship. 2) The Chinese government’s contested discourses on the English language education reflect its ambivalent attitudes towards the West, as well as an undercurrent worry about its national identity in an age of globalization and cultural hybridity
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling
The kinases MSK1 and MSK2 are activated 'downstream' of the p38 and Erk1/2 mitogen-activated protein kinases. Here we found that MSK1 and MSK2 were needed to limit the production of proinflammatory cytokines in response to stimulation of primary macrophages with lipopolysaccharide. By inducing transcription of the mitogen-activated protein kinase phosphatase DUSP1 and the anti-inflammatory cytokine interleukin 10, MSK1 and MSK2 exerted many negative feedback mechanisms. Deficiency in MSK1 and MSK2 prevented the binding of phosphorylated transcription factors CREB and ATF1 to the promoters of the genes encoding interleukin 10 and DUSP1. Mice doubly deficient in MSK1 and MSK2 were hypersensitive to lipopolysaccharide-induced endotoxic shock and showed prolonged inflammation in a model of toxic contact eczema induced by phorbol 12-myristate 13-acetate. Our results establish MSK1 and MSK2 as key components of negative feedback mechanisms needed to limit Toll-like receptor-driven inflammation.</p
Development of Photonic Crystal Fiber Based Gas/ Chemical Sensors
The development of highly-sensitive and miniaturized sensors that capable of
real-time analytes detection is highly desirable. Nowadays, toxic or colorless
gas detection, air pollution monitoring, harmful chemical, pressure, strain,
humidity, and temperature sensors based on photonic crystal fiber (PCF) are
increasing rapidly due to its compact structure, fast response and efficient
light controlling capabilities. The propagating light through the PCF can be
controlled by varying the structural parameters and core-cladding materials, as
a result, evanescent field can be enhanced significantly which is the main
component of the PCF based gas/chemical sensors. The aim of this chapter is to
(1) describe the principle operation of PCF based gas/ chemical sensors, (2)
discuss the important PCF properties for optical sensors, (3) extensively
discuss the different types of microstructured optical fiber based gas/
chemical sensors, (4) study the effects of different core-cladding shapes, and
fiber background materials on sensing performance, and (5) highlight the main
challenges of PCF based gas/ chemical sensors and possible solutions
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