Rippling: Towards untamed domesticity

The paper proposes ‘rippling' as a practice of untamed domesticity that contests the hegemony of the essentialised model of modern nuclear family and its associated domesticity. The conceptualisation of ‘rippling' derives from a context of the dissolved household in contemporary rural China — they are families of China's 285 million floating population who have seen the absence of a middle generation. At the intersection of architecture and anthropology, and with Shigushan village in Wuhan as the primary site of fieldwork since 2015, the point of entry is spatial and ethnographic observations and documentations of everyday practice in and around ordinary self-built family houses. The material traces and empirical evidence manifest a constantly diffused distinction between the domestic and the public, enacted by the rural dissolved household. In this way, the practice of ‘rippling' defies the confinement and codification of domesticity. Importantly, ‘rippling' and ‘dissolving' are a temporary, transient state that has become part of a broader structure rather than an exception. Through inhabiting and altering a multiplicity of spatial, social, and political thresholds, an elastic form of association is enacted, through which the act of mediating between genders, generations, households, neighbours, and the village community is constantly framed, and even spreads to the city through ‘floating’. Spatially stretched from house to territory and temporally coordinated from daily to multi-year cycles, domesticity as such is untamed

Standard block and modular dwelling designs in Hong Kong’s public housing

This paper examines the role of standard block and modular dwelling designs in Hong Kong’s public housing provision since the mid-1950s. It explores how standard types have evolved in relation to housing policies, demographic and socio-economic changes, and minimum space requirements. In contrast to other countries, Hong Kong lacks defined space or room standards. In the absence of space standards, Hong Kong relies on a living density standard. This paper studies the historical development of Hong Kong’s public housing in terms of dwelling size as a measure of housing quality, questioning the effectiveness of standard block and dwelling designs as housing design controls and highlighting the contextual nature of dwelling usability and size. The analysis is based on public housing design projects, policies, and data implemented or presented by the Hong Kong government, particularly the Hong Kong Housing Authority

The impact of dietary fiber on colorectal cancer patients based on machine learning

ObjectiveThis study aimed to evaluate the impact of enteral nutrition with dietary fiber on patients undergoing laparoscopic colorectal cancer (CRC) surgery.MethodsBetween January 2023 and August 2024, 164 CRC patients were randomly assigned to two groups at our hospital. The control group received standard nutritional intervention, while the observation group received enteral nutritional support containing dietary fiber. Both groups were subjected to intervention and continuously observed until the 14th postoperative day. An observational analysis assessed the impact of dietary fiber intake on postoperative nutritional status in CRC patients. The study compared infection stress index, inflammatory factors, nutritional status, intestinal function recovery, and complication incidence between groups. Additionally, four machine learning models—Logistic Regression (LR), Random Forest (RF), Neural Network (NN), and Support Vector Machine (SVM)—were developed based on nutritional and clinical indicators.ResultsIn the observation group, levels of procalcitonin (PCT), beta-endorphin (β-EP), C-reactive protein (CRP), interleukin-1 (IL-1), interleukin-8 (IL-8), and tumor necrosis factor-alpha (TNF-α) were significantly lower compared to the control group (p < 0.01). Conversely, levels of albumin (ALB), hemoglobin (HB), transferrin (TRF), and prealbumin (PAB) in the observation group were significantly higher than those in the control group (p < 0.01). Furthermore, LR, RF, NN, and SVM models can effectively predict the effects of dietary fiber on the immune function and inflammatory response of postoperative CRC patients, with the NN model performing the best. Through the screening of machine learning models, four key predictors for CRC patients were identified: PCT, PAB, ALB, and IL-1.ConclusionPostoperative dietary fiber administration in colorectal cancer enhances immune function, reduces disease-related inflammation, and inhibits tumor proliferation. Machine learning-based CRC prediction models hold clinical value

Roles of NR1I3 and NR1H4 polymorphisms in the susceptibility to antituberculosis drug-induced liver injury in China: a case‒control study

ObjectiveThe pathogenesis of antituberculosis drug-induced liver injury (AT-DILI) remains largely unknown. The current investigation aimed to determine the genetic contribution of the nuclear receptor subfamily 1 Group I member 3 (NR1I3) and nuclear receptor subfamily 1 Group H member 4 (NR1H4) genes to the risk of AT-DILI in the Chinese population.MethodsA 1:4 matched case‒control study was conducted, and five single nucleotide polymorphisms (SNPs) in the NR1I3 and NR1H4 genes were detected and assessed. Utilizing a multivariate conditional logistic regression model, the effects of haplotype and genotype on the risk of AT-DILI were examined. Extended subgroup analysis was carried out based on sex. The distribution of the peak value of serum liver enzymes also compared among different genotypes.Results224 AT-DILI cases and 896 controls were included in this study. No significant difference was observed in genotypes or haplotypes frequencies between AT-DILI cases and controls. However, comparisons of liver function indicators revealed significant differences in the peak values of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBil) among patients with different genotypes of NR1H4 rs56163822 (GG vs. GT vs. TT, 27.1 U/L vs. 26.0 U/L vs. 23.0 U/L, p = 0.020; 34.0 U/L vs. 31.0 U/L vs. 30.6 U/L, p = 0.008; 15.5 μmol/L vs. 15.0 μmol/L vs. 13.7 μmol/L, p = 0.029, respectively), as well as in the peak values of ALT and AST among male patients with different genotypes of NR1H4 rs56163822 (29.0 U/L vs. 26.9 U/L vs. 22.6 U/L, p = 0.002; 34.0 U/L vs. 32.0 U/L vs. 30.5 U/L, p = 0.019, respectively).ConclusionBased on this 1:4 individual-matched case‒control study, the SNP rs56163822 in the NR1H4 gene may be linked to the susceptibility to AT-DILI in Chinese patients receiving anti-TB treatment. Further studies in larger varied populations are needed to validate our findings

The Effect of Chinese Herbal Medicine on Albuminuria Levels in Patients with Diabetic Nephropathy: A Systematic Review and Meta-Analysis

To evaluate the effect of Chinese herbal medicine (CHM) on albuminuria levels in patients with diabetic nephropathy (DN), we performed comprehensive searches on Medline database, Cochrane Library, CNKI database, CBM database, Wanfang database, and VIP database up to December 2012. A total of 29 trials including 2440 participants with DN met the selection criteria. CHM was tested to be more effective in reducing urinary albumin excretion rate (UAER) (MD −82.95 μg/min, [−138.64, −27.26]) and proteinuria (MD −565.99 mg/24 h, [−892.41, −239.57]) compared with placebo. CHM had a greater beneficial effect on reduction of UAER (MD −13.41 μg/min, [−20.63, −6.19]) and proteinuria (MD −87.48 mg/24 h, [−142.90, −32.06]) compared with angiotensin converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB). Combination therapy with CHM and ACEI/ARB showed significant improvement in UAER (MD −28.18 μg/min, [−44.4, −11.97]), urinary albumin-creatinine ratio (MD −347.00, [−410.61, −283.39]), protein-creatinine ratio (MD −2.49, [−4.02, −0.96]), and proteinuria (MD −26.60 mg/24 h, [−26.73, −26.47]) compared with ACEI/ARB alone. No serious adverse events were reported. CHM seems to be an effective and safe therapy option to treat proteinuric patients with DN, suggesting that further study of CHM in the treatment of DN is warranted in rigorously designed, multicentre, large-scale trials with higher quality worldwide

Associations between breakfast eating habits and health-promoting lifestyle, suboptimal health status in Southern China: a population based, cross sectional study

BACKGROUND: Suboptimal health status (SHS) is the intermediate health state between health and disease, refers to medically undiagnosed or functional somatic syndromes, and has been a major global public health challenge. However, both the etiology and mechanisms associated with SHS are still unclear. Breakfast eating behavior is a dietary pattern marker and previous studies have presented evidence of associations between failure to consume breakfast and increased diseases. Accordingly, in view of the significance of breakfast eating behaviors with respect to health status, the associations between breakfast eating habits and healthy lifestyle, SHS require further elucidation. METHODS: A cross-sectional survey was conducted within a clustered sample of 24,159 individuals aged 12–80 years in 2012–13 within the population of Southern China. Breakfast eating habits were categorically defined by consumption frequency (‘scarcely, sometimes or always’). Health-promoting lifestyle was assessed via the health-promoting lifestyle profile (HPLP-II). SHS was evaluated using the medical examination report and Sub-health Measurement Scale V1.0 (SHMS V1.0). RESULTS: Of the 24,159 participants, the prevalence rates for the ‘health’ , ‘SHS’ , and ‘disease’ were 18.8%, 46.0%, and 35.2%, respectively. Overall, 19.6% of participants reported ‘scarce’ breakfast eating habits, with frequent breakfast eaters scoring higher on both HPLP-II and SHMS V1.0. After demographic adjustment, regression analyses revealed a significant association between breakfast eating habits and healthy lifestyle (p <0.001). There were lower levels of breakfast consumption regularity amongst individuals with SHS than those with disease. Categorically ‘scarce’ breakfast eaters were approximately three times more likely to be assigned SHS (OR: 2.745, 95% CI: 2.468-3.053), while infrequent breakfast eaters (‘sometimes’) were just less than twice as likely to be assessed as being of SHS (OR: 1.731, 95% CI: 1.595-1.879). CONCLUSIONS: Breakfast eating habits are significantly associated with a healthy lifestyle, and appear to be a useful predictor of a healthy lifestyle. Irregular breakfast eating habits are related to an increased risk of SHS; increased breakfast eating frequency may contribute to lowering the prevalence of SHS in Southern China. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12967-014-0348-1) contains supplementary material, which is available to authorized users

The socio-spatial design of community and governance: Interdisciplinary urban design in China

This book proposes a new interdisciplinary understanding of urban design in China based on a study of the transformative effects of socio-spatial design and planning on communities and their governance. This is framed by an examination of the social projects, spaces, and realities that have shaped three contexts critical to the understanding of urban design problems in China: the histories of “collective forms” and “collective spaces”, such as that of the urban danwei (work-unit), which inform current community building and planning; socio-spatial changes in urban and rural development; and disparate practices of “spatialised governmentality”. These contexts and an attendant transformation from planning to design and from government to governance, define the current urban design challenges found in the dominant urban xiaoqu (small district) and shequ (community) development model. Examining the histories, transformations, and practices that have shaped socio-spatial epistemologies and experiences in China – including a specific sense of community and place that is rather based on a concrete “collective” than abstract “public” space and underpinned by socialised governance – this book brings together a diverse range of observations, thoughts, analyses, and projects by urban researchers and practitioners. Thereby discussing emerging interdisciplinary urban design practices in China, this book offers a valuable resource for all academics, practitioners, and stakeholders with an interest in socio-spatial design and development

Foundation models and intelligent decision-making: Progress, challenges, and perspectives

Intelligent Decision-Making (IDM) is a cornerstone of artificial intelligence (AI), designed to automate or augment decision processes. Modern IDM paradigms integrate advanced frameworks to enable intelligent agents to make effective and adaptive choices and decompose complex tasks into manageable steps, such as AI agents and high-level reinforcement learning. Recent advances in multimodal foundation-based approaches unify diverse input modalities—such as vision, language, and sensory data—into a cohesive decision-making process. Foundation Models (FMs) have become pivotal in science and industry, trans- forming decision-making and research capabilities. Their large-scale, multimodal data-processing abilities foster adaptability and interdisciplinary breakthroughs across fields such as healthcare, life sciences, and education. This survey examines IDM’s evolution, advanced paradigms with FMs, and their transformative impact on decision-making across diverse scientific and industrial domains, highlighting the challenges and opportunities in building efficient, adaptive, and ethical decision systems.<br/

Territory, Settlement, Household: A Project of Rural China

The thesis recognises the countryside as a specific social, cultural and political construct rather than as ancillary to the city. It challenges current strategies of rural regeneration in China, which heavily rely on models of urbanisation, as well as the prevailing mentality that views the countryside as not just economically but also culturally and intellectually under-developed. The key research question is thus: what does being rural mean socio-spatially? Structured by three main studies of the rural-urban relationship, the cross-scalar framework and research by design, the thesis explores ‘rurality’ as a spatial question at the levels of territory, settlement and household. In the studies, the case study method, fieldwork and drawing play essential roles. Based on the understanding of rurality as an elastic form of association in both social and spatial terms and across scales, the thesis advocates a shift in design thinking for the rural and proposes the integration of planning, urban design and architecture, in order to create one synthetic design discipline capable of facilitating an alternative multi-scalar rural regeneration model. The aim of this discipline is to create opportunities of change in the recognised and established field of power and is in this sense political. Furthermore, the thesis calls for integrating the spatial, social and cultural history and the transformations of rural China into a larger economic and political debate in order to transcend the conceptual limitations of the current rural discourse and to rethink rural development as a socio-cultural process. Given that a self-organised support system underpinned by associational relationships in rural society embodies a rooted cultural unity in China, the thesis argues that rurality, or an elastic form of association, transcends the simple divide between urban and rural development by providing a distinct form of living arrangement and social organisation. In this sense, rurality is ultimately about how people organise themselves and associate with others

Collective Forms in China: People’s Commune and Danwei

Collective forms are simultaneously governmental forms, social forms, organisational forms, and spatial forms, but can also incorporate economic forms or political forms. From this perspective, urban and rural areas in socialist China were predominantly planned and managed as semi-autonomous collective forms. People’s Commune and Danwei are two exemplary cases among others. The research reviews their conception as social projects and the social realities they produced, while examining their often overlooked legacies for discourses in architecture and urban design. Through discussing the research methodology, cases of collective forms in the West, the historical context of China’s People’s Commune and Danwei, and two built cases in Wuhan, this paper argues that collective forms are not simply related to a historical period of collectivisation, but to past, present, and future forms shaped by collective subjectivities and the important underlying shared norms and demands to achieve common goals and benefits