Heterogeneous Fluorescence Intermittency in Single Layer Reduced Graphene Oxide

We provide, for the first time, direct experimental evidence for heterogeneous blinking in reduced graphene oxide (rGO) during photolysis. The spatially resolved intermittency originates from regions within individual rGO sheets and shows 1/f-like power spectral density. We describe the evolution of rGO blinking using the multiple recombination center (MRC) model that captures common features of nanoscale blinking. Our results illustrate the universal nature of blinking and suggest a common microscopic origin for the effect

Drug treatment of breast cancer brain metastases: progress and challenges

Abstract Breast cancer is one of the most prevalent malignancies among women worldwide, with brain metastasis occurring in approximately 10–16% of cases, significantly contributing to poor prognosis and reduced quality of life. The treatment of breast cancer brain metastasis requires a multidisciplinary approach, prioritizing local therapies such as surgery and radiotherapy to address central nervous system lesions. However, local treatments often struggle to effectively control the progression of brain metastases and are associated with multiple complications, necessitating adjunctive systemic and supportive therapies. Following local therapy, breast cancer brain metastasis patients may benefit from systemic treatments. Pharmacological therapies, including chemotherapy, targeted therapy, immunotherapy, and antibody–drug conjugates, have emerged as vital strategies for breast cancer brain metastasis treatment. Targeted therapies combined with stereotactic radiosurgery and surgical resection have shown improved survival rates. However, challenges remain, such as high costs, limited availability of radiotherapy equipment, and individualized treatment requirements based on lesion characteristics and systemic disease control. Further advancements in pharmacological options, particularly targeted and immune therapies, offer promising avenues for improving outcomes and survival in breast cancer brain metastasis patients

Study on Durability and Dynamic Deicing Performance of Elastomeric Coatings on Wind Turbine Blades

Durable elastomeric deicing coatings were developed for the anti-icing and deicing of wind turbine blades in this study. Our developed deicing coatings demonstrated extremely low ice adhesion strength (~15 kPa). Silica was added to enhance the icephobic surfaces’ durability. The life of the deicing coating with silica was extended by 1.2 times. After 168 h of xenon lamp irradiation, there were no significant changes in the chemical composition of the coatings. Due to the increasing roughness and the decreasing tensile modulus, the contact angle of the aged coatings decreased by 14°. Further outdoor research was carried out on a wind farm for two months to investigate the influence of natural insolation and wind erosion on the elastic deicing coatings. The aged coating still maintained a high hydrophobicity and low ice adhesion strength. The contact angle stabilized at 107°, and the ice adhesion strength was 75% lower than that of the uncoated wind turbine blade. The elastomeric deicing coatings had three advantages: a lagging freezing time, low ice accumulation, and a short icing/deicing cycle. The results of field experiments on the naturally aged coatings showed that the freezing time of the coated blade was delayed by 20 min, and the ice on the coated blade was 29% thinner than that on the uncoated blade

MOF-derived TiO₂ modified with g-C₃N₄ nanosheets for enhanced visible-light photocatalytic performance

A g-C3N4/TiO2 heterojunction was prepared for the first time using a mechanical agitation method assisted by a template method and a two-step calcination method.</p

280–300 GHz SiGe‐InP hybrid‐integrated transmitter with 21.9 dBm EIRP and 10 Gbps data rate

Abstract In this paper, a 280–300 GHz hybrid‐integrated transmitter is proposed. The advantages of the SiGe and InP chips are fully made use by integrating these two chips. For low cost and high integration, the local oscillator chain and mixer are based on chips in SiGe technology, and the 300‐GHz power amplifier and on‐chip antenna are realised in InP technology for high output power and small die size. The low‐cost bonding wires are introduced for the interconnection between these two chips, and the lens are attached above the on‐chip antenna for further EIRP enhancement. Finally, the proposed transmitter is fabricated and measured, which shows comparable performances with 21.9 dBm EIRP (equivalent isotropic radiated power) and 10 Gbps data rate