582 research outputs found
Ultra-cold mechanical resonators coupled to atoms in an optical lattice
We propose an experiment utilizing an array of cooled micro-cantilevers
coupled to a sample of ultra-cold atoms trapped near a micro-fabricated
surface. The cantilevers allow individual lattice site addressing for atomic
state control and readout, and potentially may be useful in optical lattice
quantum computation schemes. Assuming resonators can be cooled to their
vibrational ground state, the implementation of a two-qubit controlled-NOT gate
with atomic internal states and the motional states of the resonator is
described. We also consider a protocol for entangling two or more cantilevers
on the atom chip with different resonance frequencies, using the trapped atoms
as an intermediary. Although similar experiments could be carried out with
magnetic microchip traps, the optical confinement scheme we consider may
exhibit reduced near-field magnetic noise and decoherence. Prospects for using
this novel system for tests of quantum mechanics at macroscopic scales or
quantum information processing are discussed.Comment: 5 pages, 3 figure
Improved constraints on non-Newtonian forces at 10 microns
Several recent theories suggest that light moduli or particles in "large"
extra dimensions could mediate macroscopic forces exceeding gravitational
strength at length scales below a millimeter. Such new forces can be
parameterized as a Yukawa-type correction to the Newtonian potential of
strength relative to gravity and range . To extend the search
for such new physics we have improved our apparatus utilizing cryogenic
micro-cantilevers capable of measuring attonewton forces, which now includes a
switchable magnetic force for calibration. Our most recent experimental
constraints on Yukawa-type deviations from Newtonian gravity are more than
three times as stringent as our previously published results, and represent the
best bound in the range of 5 - 15 microns, with a 95 percent confidence
exclusion of forces with at = 10 microns.Comment: 12 pages, 9 figures, accepted for publication in PRD. Minor changes,
replaced and corrected Figs 4,5,
Short-range force detection using optically-cooled levitated microspheres
We propose an experiment using optically trapped and cooled dielectric
microspheres for the detection of short-range forces. The center-of-mass motion
of a microsphere trapped in vacuum can experience extremely low dissipation and
quality factors of , leading to yoctonewton force sensitivity.
Trapping the sphere in an optical field enables positioning at less than 1
m from a surface, a regime where exotic new forces may exist. We expect
that the proposed system could advance the search for non-Newtonian gravity
forces via an enhanced sensitivity of over current experiments at
the 1 m length scale. Moreover, our system may be useful for
characterizing other short-range physics such as Casimir forces.Comment: 4 pages, 3 figures, minor changes, Figs. 1 and 2 replace
Resonant interaction of trapped cold atoms with a magnetic cantilever tip
Magnetic resonance in an ensemble of laser-cooled trapped Rb atoms is excited
using a micro- cantilever with a magnetic tip. The cantilever is mounted on a
multi-layer chip designed to capture, cool, and magnetically transport cold
atoms. The coupling is observed by measuring the loss from a magnetic trap as
the oscillating cantilever induces Zeeman state transitions in the atoms.
Interfacing cold atoms with mechanical devices could enable probing and
manipulating atomic spins with nanometer spatial resolution and single-spin
sensitivity, leading to new capabilities in quantum computation, quantum
simulation, or precision sensing.Comment: 5 pages, 4 figure
Contribution of thirdhand smoke to overall tobacco smoke exposure in pediatric patients: study protocol.
BackgroundThirdhand smoke (THS) is the persistent residue resulting from secondhand smoke (SHS) that accumulates in dust, objects, and on surfaces in homes where tobacco has been used, and is reemitted into air. Very little is known about the extent to which THS contributes to children's overall tobacco smoke exposure (OTS) levels, defined as their combined THS and SHS exposure. Even less is known about the effect of OTS and THS on children's health. This project will examine how different home smoking behaviors contribute to THS and OTS and if levels of THS are associated with respiratory illnesses in nonsmoking children.MethodsThis project leverages the experimental design from an ongoing pediatric emergency department-based tobacco cessation trial of caregivers who smoke and their children (NIHR01HD083354). At baseline and follow-up, we will collect urine and handwipe samples from children and samples of dust and air from the homes of smokers who smoke indoors, have smoking bans or who have quit smoking. These samples will be analyzed to examine to what extent THS pollution at home contributes to OTS exposure over and above SHS and to what extent THS continues to persist and contribute to OTS in homes of smokers who have quit or have smoking bans. Targeted and nontargeted chemical analyses of home dust samples will explore which types of THS pollutants are present in homes. Electronic medical record review will examine if THS and OTS levels are associated with child respiratory illness. Additionally, a repository of child and environmental samples will be created.DiscussionThe results of this study will be crucial to help close gaps in our understanding of the types, quantity, and clinical effects of OTS, THS exposure, and THS pollutants in a unique sample of tobacco smoke-exposed ill children and their homes. The potential impact of these findings is substantial, as currently the level of risk in OTS attributable to THS is unknown. This research has the potential to change how we protect children from OTS, by recognizing that SHS and THS exposure needs to be addressed separately and jointly as sources of pollution and exposure.Trial registrationClinicalTrials.gov Identifier: NCT02531594 . Date of registration: August 24, 2015
Characterizing the small RNA transcriptome associated with COPD and ILD using next-generation sequencing
Moving Beyond Gene Expression: Identification of Lung-Disease-Associated Novel Transcripts and Alternative Splicing by RNA Sequencing
New species of Cheumatopsyche (Trichoptera: Hydropsychidae) from North Sulawesi, Indonesia
Sulawesi Island has a high density of endemic animal species, including insects in the order Trichoptera. We describe the males of four new species of Cheumatopsyche (Trichoptera: Hydropsychidae) from North Sulawesi (Provinsi Sulawesi Utara), and provide a checklist of the Cheumatopsyche species from the Indonesian archipelago. Describing the aquatic insect fauna is an important step toward establishing biomonitoring protocols in Indonesia, which is experiencing rapid development and water pollution problems
Comprehensive Genomic Profiling of the Lung Transcriptome in Emphysema and Idiopathic Pulmonary Fibrosis Using RNA-Seq
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