Molecule Microscopy

Contains research objectives and reports on three research projects.Francis L. Friedman ChairNational Institutes of Health (Grant AM-31546

Molecule Microscopy

Contains reports on two research projects.National Institutes of Health (Grant 1 ROI GM23678)Health Sciences Fun

Recruitment, growth and mortality of an Antarctic hexactinellid sponge, Anoxycalyx joubini.

Polar ecosystems are sensitive to climate forcing, and we often lack baselines to evaluate changes. Here we report a nearly 50-year study in which a sudden shift in the population dynamics of an ecologically important, structure-forming hexactinellid sponge, Anoxycalyx joubini was observed. This is the largest Antarctic sponge, with individuals growing over two meters tall. In order to investigate life history characteristics of Antarctic marine invertebrates, artificial substrata were deployed at a number of sites in the southern portion of the Ross Sea between 1967 and 1975. Over a 22-year period, no growth or settlement was recorded for A. joubini on these substrata; however, in 2004 and 2010, A. joubini was observed to have settled and grown to large sizes on some but not all artificial substrata. This single settlement and growth event correlates with a region-wide shift in phytoplankton productivity driven by the calving of a massive iceberg. We also report almost complete mortality of large sponges followed over 40 years. Given our warming global climate, similar system-wide changes are expected in the future

Molecule Microscopy

Contains research objectives and reports on four research projects.National Institutes of Health (Grant AM-25535)Whitaker FoundationFrancis L. Friedman Chai

Molecule Microscopy

Contains research objectives and reports on seven research projects.Whitaker Health Sciences FundFrancis L. Friedman ChairNational Institutes of Health (Grant AM-31546)National Institutes of Health (Grant AM-25535)International Business Machines, Inc

Neutrality of Molecules by the Pulsed Gas Flow Method

Contains an introduction and a description on one research project.F.L. Friedman Chai

Molecule Microscopy

Contains research objectives, summary of research on five research projects and reports on four research projects.Joint Services Electronics Program (Contract DAAB07-74-C-0630)National Institutes of Health (Grant 1 PO1 HL14322-03)National Institutes of Health (Grant 5 SO5 RR07047-08)Environmental Measurements Project Laboratory grant from the Dean of Science, M.I.T.Boehringer Mannheim Gmb

Pain Testing in Endometriosis for the Clinician

Clinical pain testing has been used to ascertain the pathophysiology of many clinical conditions, but its use in the management of endometriosis has been limited. Although the testing can require the use of complex testing in the laboratory, this chapter is directed to look at a test for allodynia that can be applied in the clinic. The test for cutaneous allodynia is validated, does not require sophisticated tools, and is readily accepted by woman. The presence of allodynia in certain gynecological presentations can indicate the woman’s pain system has become sensitized. Uses of the test in clinical encounters with women suffering from endometriosis and possible uses in future are presented