6,388 research outputs found
Social Deprivation and Exclusion of Immigrants in Germany
This paper aims at providing empirical evidence on social exclusion of immigrants in Germany. We demonstrate that when using a conventional definition of the social inclusion index typically applied in the literature, immigrants appear to experience a significant degree of social deprivation and exclusion, confirming much of the economic literature examining the economic assimilation of immigrants in Germany. We propose a weighting scheme that weights components of social inclusion by their subjective contribution to an overall measure of life satisfaction.Using this weighting scheme to calculate an index of social inclusion, we find that immigrants are in fact as "included" as Germans. This result is driven strongly by the disproportionately positive socio-demographic characteristics that immigrants possess as measured by the contribution to their life satisfaction.Social Exclusion, International Migration, Integration
UV spectra of iron-doped carbon clusters FeC_n n = 3-6
Electronic transitions of jet-cooled FeC clusters () were
measured between 230 and 300 nm by a mass-resolved 1+1 resonant two-photon
ionization technique. Rotational profiles were simulated based on previous
calculations of ground state geometries and compared to experimental
observations. Reasonable agreement is found for the planar fan-like structure
of FeC. The FeC data indicate a shorter distance between the Fe atom
and the bent C unit of the fan. The transitions are suggested to be
AB for FeC and AA for FeC. In contrast to the predicted C
geometry, non-linear FeC is apparently observed. Line width broadening
prevents analysis of the FeC spectrum.Comment: 6 pages, 5 figure
Extracting partition statistics from semistructured data
The effective grouping, or partitioning, of semistructured data is of fundamental importance when providing support for queries. Partitions allow items within the data set that share common structural properties to be identified efficiently. This allows queries that make use of these properties, such as branching path expressions, to be accelerated. Here, we evaluate the effectiveness of several partitioning techniques by establishing the number of partitions that each scheme can identify over a given data set. In particular, we explore the use of parameterised indexes, based upon the notion of forward and backward bisimilarity, as a means of partitioning semistructured data; demonstrating that even restricted instances of such indexes can be used to identify the majority of relevant partitions in the data
Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma
The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical models. Our purpose was to determine the potential of radiosensitizers to enhance the anti-tumor efficacy of [131I]MIP-1145. Melanotic (A2058) and amelanotic (A375 and SK-N-BE(2c)) cells were treated with [131I]MIP-1145 as a single agent or in combination with drugs with radiosenitizing potential. Cellular uptake of [131I]MIP-1145 and toxicity were assessed in monolayer culture. The interaction between radiosensitizers and [131I]MIP-1145 was evaluated by combination index analysis in monolayer cultures and by delayed growth of multicellular tumor spheroids. [131I]MIP-1145 was taken up by and was toxic to melanotic cells but not amelanotic cells. Combination treatments comprising [131I]MIP-1145 with the topoisomerase inhibitor topotecan or the PARP-1 inhibitor AG014699 resulted in synergistic clonogenic cell kill and enhanced delay of the growth of spheroids derived from melanotic melanoma cells. The proteasome inhibitor bortezomib had no synergistic cytotoxic effect with [131I]MIP-1145 and failed to enhance the delay of spheroid growth. Following combination treatment of amelanotic cells, neither synergistic clonogenic cell kill nor enhanced growth delay of spheroids was observed
Social Deprivation and Exclusion of Immigrants in Germany
This paper aims at providing empirical evidence on social exclusion of immigrants in Germany. We demonstrate that when using a conventional definition of the social inclusion index typically applied in the literature, immigrants appear to experience a significant degree of social deprivation and exclusion, confirming much of the economic literature examining the economic assimilation of immigrants in Germany. We propose a weighting scheme that weights components of social inclusion by their subjective contribution to an overall measure of life satisfaction. Using this weighting scheme to calculate an index of social inclusion, we find that immigrants are in fact as "included" as Germans. This result is driven strongly by the disproportionately positive socio- demographic characteristics that immigrants possess as measured by the contribution to their life satisfaction.Social exclusion, international migration, integration
Dynamic Compartments in the Imperative Pi Calculus
International audienceDynamic compartments with mutable configurations and variable volumes are of basic interest for the stochastic modeling of biochemistry in cells. We propose a new language to express dynamic compartments that we call the imperative π-calculus. It is obtained from the attributed π-calculus by adding imperative assignment operations to a global store. Previous approaches to dynamic compartments are improved in flexibility or efficiency. This is illustrated by an appropriate model of osmosis and a correct encoding of BioAmbients
Electronic spectra of linear HCH and cumulene carbene HC
The transition of linear HCH
(A) has been observed in a neon matrix and gas phase. The assignment is based
on mass-selective experiments, extrapolation of previous results of the longer
HCH homologues, and density functional and multi-state CASPT2
theoretical methods. Another band system starting at 303 nm in neon is assigned
as the transition of the cumulene carbene
pentatetraenylidene HC (B).Comment: 7 pages, 4 figures, 5 table
Visible Absorptions of Potential Diffuse ISM Hydrocarbons: C9H9 and C9H5 Radicals
The laboratory detection of previously unobserved resonance-stabilized C9H5 and C9H9 radicals in the supersonic expansion of a hydrocarbon discharge source is reported. The radicals are tentatively assigned as acetylenic-substituted cyclopentadienyl C9H5 and vinyl-substituted benzyl C9H9 species. They are found to feature visible absorption bands that coincide with a few very weak diffuse interstellar bands toward HD183143 and HD204827
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