6,388 research outputs found

    Social Deprivation and Exclusion of Immigrants in Germany

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    This paper aims at providing empirical evidence on social exclusion of immigrants in Germany. We demonstrate that when using a conventional definition of the social inclusion index typically applied in the literature, immigrants appear to experience a significant degree of social deprivation and exclusion, confirming much of the economic literature examining the economic assimilation of immigrants in Germany. We propose a weighting scheme that weights components of social inclusion by their subjective contribution to an overall measure of life satisfaction.Using this weighting scheme to calculate an index of social inclusion, we find that immigrants are in fact as "included" as Germans. This result is driven strongly by the disproportionately positive socio-demographic characteristics that immigrants possess as measured by the contribution to their life satisfaction.Social Exclusion, International Migration, Integration

    UV spectra of iron-doped carbon clusters FeC_n n = 3-6

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    Electronic transitions of jet-cooled FeCn_n clusters (n=36n = 3 - 6) were measured between 230 and 300 nm by a mass-resolved 1+1 resonant two-photon ionization technique. Rotational profiles were simulated based on previous calculations of ground state geometries and compared to experimental observations. Reasonable agreement is found for the planar fan-like structure of FeC3_3. The FeC4_4 data indicate a shorter distance between the Fe atom and the bent C4_4 unit of the fan. The transitions are suggested to be 3^{3}A23_{2} \leftarrow ^{3}B1_{1} for FeC3_3 and 5^{5}A15_{1} \leftarrow ^{5}A1_{1} for FeC4_4. In contrast to the predicted Cv_{\infty \text{v}} geometry, non-linear FeC5_5 is apparently observed. Line width broadening prevents analysis of the FeC6_6 spectrum.Comment: 6 pages, 5 figure

    Extracting partition statistics from semistructured data

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    The effective grouping, or partitioning, of semistructured data is of fundamental importance when providing support for queries. Partitions allow items within the data set that share common structural properties to be identified efficiently. This allows queries that make use of these properties, such as branching path expressions, to be accelerated. Here, we evaluate the effectiveness of several partitioning techniques by establishing the number of partitions that each scheme can identify over a given data set. In particular, we explore the use of parameterised indexes, based upon the notion of forward and backward bisimilarity, as a means of partitioning semistructured data; demonstrating that even restricted instances of such indexes can be used to identify the majority of relevant partitions in the data

    Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma

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    The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical models. Our purpose was to determine the potential of radiosensitizers to enhance the anti-tumor efficacy of [131I]MIP-1145. Melanotic (A2058) and amelanotic (A375 and SK-N-BE(2c)) cells were treated with [131I]MIP-1145 as a single agent or in combination with drugs with radiosenitizing potential. Cellular uptake of [131I]MIP-1145 and toxicity were assessed in monolayer culture. The interaction between radiosensitizers and [131I]MIP-1145 was evaluated by combination index analysis in monolayer cultures and by delayed growth of multicellular tumor spheroids. [131I]MIP-1145 was taken up by and was toxic to melanotic cells but not amelanotic cells. Combination treatments comprising [131I]MIP-1145 with the topoisomerase inhibitor topotecan or the PARP-1 inhibitor AG014699 resulted in synergistic clonogenic cell kill and enhanced delay of the growth of spheroids derived from melanotic melanoma cells. The proteasome inhibitor bortezomib had no synergistic cytotoxic effect with [131I]MIP-1145 and failed to enhance the delay of spheroid growth. Following combination treatment of amelanotic cells, neither synergistic clonogenic cell kill nor enhanced growth delay of spheroids was observed

    Social Deprivation and Exclusion of Immigrants in Germany

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    This paper aims at providing empirical evidence on social exclusion of immigrants in Germany. We demonstrate that when using a conventional definition of the social inclusion index typically applied in the literature, immigrants appear to experience a significant degree of social deprivation and exclusion, confirming much of the economic literature examining the economic assimilation of immigrants in Germany. We propose a weighting scheme that weights components of social inclusion by their subjective contribution to an overall measure of life satisfaction. Using this weighting scheme to calculate an index of social inclusion, we find that immigrants are in fact as "included" as Germans. This result is driven strongly by the disproportionately positive socio- demographic characteristics that immigrants possess as measured by the contribution to their life satisfaction.Social exclusion, international migration, integration

    Dynamic Compartments in the Imperative Pi Calculus

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    International audienceDynamic compartments with mutable configurations and variable volumes are of basic interest for the stochastic modeling of biochemistry in cells. We propose a new language to express dynamic compartments that we call the imperative π-calculus. It is obtained from the attributed π-calculus by adding imperative assignment operations to a global store. Previous approaches to dynamic compartments are improved in flexibility or efficiency. This is illustrated by an appropriate model of osmosis and a correct encoding of BioAmbients

    Electronic spectra of linear HC5_5H and cumulene carbene H2_2C5_5

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    The 13ΣuX3Σg1 ^3\Sigma_u^- \leftarrow X^3\Sigma_g^- transition of linear HC5_5H (A) has been observed in a neon matrix and gas phase. The assignment is based on mass-selective experiments, extrapolation of previous results of the longer HC2n+1_{2n+1}H homologues, and density functional and multi-state CASPT2 theoretical methods. Another band system starting at 303 nm in neon is assigned as the 11A1X1A11 ^1 A_1 \leftarrow X ^1 A_1 transition of the cumulene carbene pentatetraenylidene H2_2C5_5 (B).Comment: 7 pages, 4 figures, 5 table

    Visible Absorptions of Potential Diffuse ISM Hydrocarbons: C9H9 and C9H5 Radicals

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    The laboratory detection of previously unobserved resonance-stabilized C9H5 and C9H9 radicals in the supersonic expansion of a hydrocarbon discharge source is reported. The radicals are tentatively assigned as acetylenic-substituted cyclopentadienyl C9H5 and vinyl-substituted benzyl C9H9 species. They are found to feature visible absorption bands that coincide with a few very weak diffuse interstellar bands toward HD183143 and HD204827
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