2,836 research outputs found
Ectoparasites and Other Arthropod Associates of the Hairy-tailed Mole, \u3ci\u3eParascalops Breweri\u3c/i\u3e
A total of 33 taxa of ectoparasites and other associates was taken on seven individuals of the Hairy-tailed Mole, Parascalops breweri, from New York and New England. The most abundant form was the glycyphagid mite, Labidophorus nearcticus
Ectoparasites and Other Arthropod Associates of Some Voles and Shrews From the Catskill Mountains of New York
Reported here from the Catskill Mountains of New York are 30 ectoparasites and other associates from 39 smoky shrews, Sorex fumeus, 17 from 11 masked shrews, Sorex cinereus, 11 from eight long-tailed shrews, Sorex dispar, and 31 from 44 rock voles, Microtus chrotorrhinus
Ionization behavior of the histidine residue in the catalytic triad of serine proteases
α-Lytic protease is a homologue of the mammalian serine proteases such as trypsin, chymotrypsin, and elastase, and its single histidine residue belongs to the Asp-His-Ser catalytic triad. This single histidine residue has been selectively enriched in the C-2 carbon with 13C. Magnetic resonance studies of the chemical shift and coupling constant (1Jch) behavior of this nucleus as a function of pH suggest that the imidazole ring is neutral above pH 5 and therefore that the group which is known to ionize with pKa near 6.7 must be the aspartic acid residue.
Implications of these new pKa assignments for the catalytic mechanism of serine proteases are discussed and include the absence of any need to separate charge during catalysis. The histidine residue plays two roles. (a) It insulates the aspartic acid from an aqueous environment and accordingly raises its pKa. (b) It serves as a bidentate base to accept a proton from the serine at one of its nitrogens and concertedly transfer a proton from its other nitrogen to the buried carboxylate anion during formation of the tetrahedral intermediate
Boston Hospitality Review: Winter 2017
Table of contents: Family, Team or Something Else? by John Murtha -- Kitchen Organization in Full-Service Restaurants: Reducing Heat and Stress by Peter Szende and Justin Cipriano -- Rules of Engagement: Building Brand Relationships by Alex Friedman -- Corporate Social Responsibility in the Hospitality Sector by Manisha Singal and Yinyoung Rhou -- “Hold on, I have to post this on Instagram”: Trends, Talk, and Transactions of the Experiential Consumer by Steve Kent -- C-corporation Hotels vs. Hotel-REITs: A Theoretical and Practical Comparison by Tarik Dogru -- Sisters in Restaurant Success: A History of The Maramor by Jan WhitakerFamily, Team or Something Else? by John Murtha -- Kitchen Organization in Full-Service Restaurants: Reducing Heat and Stress by Peter Szende and Justin Cipriano -- Rules of Engagement: Building Brand Relationships by Alex Friedman -- Corporate Social Responsibility in the Hospitality Sector by Manisha Singal and Yinyoung Rhou -- “Hold on, I have to post this on Instagram”: Trends, Talk, and Transactions of the Experiential Consumer by Steve Kent -- C-corporation Hotels vs. Hotel-REITs: A Theoretical and Practical Comparison by Tarik Dogru -- Sisters in Restaurant Success: A History of The Maramor by Jan Whitake
Solar park microclimate and vegetation management effects on grassland carbon cycling
Increasing energy demands and the drive towards low carbon (C) energy sources has prompted a rapid increase in ground-mounted solar parks across the world. This represents a significant global land use change with implications for the hosting ecosystems that are poorly understood. In order to investigate the effects of a typical solar park on the microclimate and ecosystem processes, we measured soil and air microclimate, vegetation and greenhouse gas emissions for twelve months under photovoltaic (PV) arrays, in gaps between PV arrays and in control areas at a UK solar park sited on species-rich grassland. Our results show that the PV arrays caused seasonal and diurnal variation in air and soil microclimate. Specifically, during the summer we observed cooling, of up to 5.2 °C, and drying under the PV arrays compared with gap and control areas. In contrast, during the winter gap areas were up to 1.7 °C cooler compared with under the PV arrays and control areas. Further, the diurnal variation in both temperature and humidity during the summer was reduced under the PV arrays. We found microclimate and vegetation management explained differences in the above ground plant biomass and species diversity, with both lower under the PV arrays. Photosynthesis and net ecosystem exchange in spring and winter were also lower under the PV arrays, explained by microclimate, soil and vegetation metrics. These data are a starting point to develop understanding of the effects of solar parks in other climates, and provide evidence to support the optimisation of solar park design and management to maximise the delivery of ecosystem services from this growing land use
In situ characterization of pin diode waveforms using electro‐optic sampling
In situ measurements of nonlinear waveforms produced by a PIN diode under large‐signal excitation have been performed using ultrafast electro‐optic (EO) sampling.The waveforms were sampled using an EO probe positioned immediately after the diode. These data validate a nonlinear model and improve representation of the waveform across the circuit. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2653–2656, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27119Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/93525/1/27119_ftp.pd
Severe conjunctivochalasis in association with classic type Ehlers-Danlos syndrome.
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are.BACKGROUND: Inferior conjunctivochalasis is common, but is rarely severe enough to require conjunctival excision. This report describes a patient with severe conjunctivochalasis who was subsequently diagnosed with Ehlers Danlos Syndrome, Classic Type. CASE PRESENTATION: A patient suffering from foreign body sensation, frequent blinking and bilateral inferior conjunctivochalasis was referred and treated by topical ocular lubrication. However, no improvement was observed prompting potential excision of conjunctivochalasis. Following patient consultation and clinical diagnosis including hypermobile joints and skin elasticity, poor wound healing and wide scar morphology, Ehlers-Danlos syndrome was confirmed in the patient. CONCLUSION: This case highlights the need for direct patient questioning and provides the first reported association between conjunctiovochalasis and Ehlers-Danlos syndrome
Design and implementation of a biomolecular concentration tracker
As a field, synthetic biology strives to engineer increasingly complex artificial systems in living cells. Active feedback in closed loop systems offers a dynamic and adaptive way to ensure constant relative activity independent of intrinsic and extrinsic noise. In this work, we use synthetic protein scaffolds as a modular and tunable mechanism for concentration tracking through negative feedback. Input to the circuit initiates scaffold production, leading to colocalization of a two-component system and resulting in the production of an inhibitory antiscaffold protein. Using a combination of modeling and experimental work, we show that the biomolecular concentration tracker circuit achieves dynamic protein concentration tracking in Escherichia coli and that steady state outputs can be tuned
Detection of Drug-Responsive T-Lymphocytes in a Case of Fatal Antituberculosis Drug-Related Liver Injury
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