5,173 research outputs found
Facing a changing labour force in China: Determinants of trust and reciprocity in an experimental labour market
Due to economic and demographic changes highly educated women are increasingly important for the Chinese labour market. Gender is a well-studied determinant of behaviour in economic experiments, as are similarly academic major, age and income. We study determinants of trust and reciprocity for Chinese subjects in a labour market experiment using two variants of a gift exchange framework with employers and workers. We find that women are significantly less trusting and less reciprocal in one game variant while this relationship is only clear for reciprocity in the other variant
Visible-Light-Induced, Copper-Catalyzed Three-Component Coupling of Alkyl Halides, Olefins, and Trifluoromethylthiolate to Generate Trifluoromethyl Thioethers
Photoinduced, copper-catalyzed coupling reactions are emerging as a powerful method for generating Csp^3–Y (Y = C or heteroatom) bonds from alkyl electrophiles and nucleophiles. Corresponding three-component couplings of alkyl electrophiles, olefins, and nucleophiles have the potential to generate an additional Csp3–Y bond and to efficiently add functional groups to both carbons of an olefin, which serves as a readily available linchpin. In this report, we establish that a variety of electrophiles and a trifluoromethylthiolate nucleophile can add across an array of olefins (including styrenes and electron-poor olefins) in the presence of CuI/binap and blue-LED irradiation, thereby generating trifluoromethyl thioethers in good yield. The process tolerates a wide range of functional groups, and an initial survey of other nucleophiles (i.e., bromide, cyanide, and azide) suggests that this three-component coupling strategy is versatile. Mechanistic studies are consistent with a photoexcited Cu(I)/binap/SCF_3 complex serving as a reductant to generate an alkyl radical from the electrophile, which likely reacts in turn with the olefin and a Cu(II)/SCF_3 complex to afford the coupling product
PENGARUH DEWAN KOMISARIS ASING, DEWAN KOMISARIS INDEPENDEN DAN KEPEMILIKAN SAHAM ASING TERHADAP NILAI PERUSAHAAN (STUDI EMPIRIS PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI TAHUN 2009-2011)
Penelitian ini bertujuan untuk menguji pengaruh dewan komisaris asing, dewan komisaris independen dan kepemilikan saham asing terhadap nilai perusahaan manufaktur yang terdaftar di BEI (Bursa Efek Indonesia) selama periode pengamatan (2009-2011).Penelitian ini merupakan penelitian empiris dengan pendekatan kuantitatif yang melibatkan penggunaan analisa statistik. Penelitian ini menggunakan data sekunder. Alat analisisnyang digunakan dalam penelitian ini adalah regresi linier berganda dengan bantuan
sofware SPSS (Statistical Package for Social Scienc)
Hasil penelitian menunjukkan bahwa dewan komisaris asing dan kepemilikan saham asing berpengaruh positif dan signifikan terhadap nilai perusahaan, sedangkan variabel
dewan komisaris independen tidak mempunyai pengaruh yang signifikan terhadap nilai perusahaan
Genetically altered AMPA-type glutamate receptor kinetics in interneurons disrupt long-range synchrony of gamma oscillation
Gamma oscillations synchronized between distant neuronal populations may be critical for binding together brain regions devoted to common processing tasks. Network modeling predicts that such synchrony depends in part on the fast time course of excitatory postsynaptic potentials (EPSPs) in interneurons, and that even moderate slowing of this time course will disrupt synchrony. We generated mice with slowed interneuron EPSPs by gene targeting, in which the gene encoding the 67-kDa form of glutamic acid decarboxylase (GAD67) was altered to drive expression of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor subunit GluR-B. GluR-B is a determinant of the relatively slow EPSPs in excitatory neurons and is normally expressed at low levels in γ-aminobutyric acid (GABA)ergic interneurons, but at high levels in the GAD-GluR-B mice. In both wild-type and GAD-GluR-B mice, tetanic stimuli evoked gamma oscillations that were indistinguishable in local field potential recordings. Remarkably, however, oscillation synchrony between spatially separated sites was severely disrupted in the mutant, in association with changes in interneuron firing patterns. The congruence between mouse and model suggests that the rapid time course of AMPA receptor-mediated EPSPs in interneurons might serve to allow gamma oscillations to synchronize over distance
SUSY parameter determination at the LHC using cross sections and kinematic edges
We study the determination of supersymmetric parameters at the LHC from a
global fit including cross sections and edges of kinematic distributions. For
illustration, we focus on a minimal supergravity scenario and discuss how well
it can be constrained at the LHC operating at 7 and 14 TeV collision energy,
respectively. We find that the inclusion of cross sections greatly improves the
accuracy of the SUSY parameter determination, and allows to reliably extract
model parameters even in the initial phase of LHC data taking with 7 TeV
collision energy and 1/fb integrated luminosity. Moreover, cross section
information may be essential to study more general scenarios, such as those
with non-universal gaugino masses, and distinguish them from minimal,
universal, models.Comment: 22 pages, 8 figure
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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we performed genome-wide analyses of circulating HDL cholesterol, LDL cholesterol, and triglyceride levels in up to 120,979 individuals of European, African, Asian, Hispanic, and Brazilian ancestry, with follow-up of suggestive associations in an additional 131,012 individuals. We find four loci, in/near CLASP1, LHX1, SNTA1, and CNTNAP2, that are associated with circulating lipid levels through interaction with physical activity; higher levels of physical activity enhance the HDL cholesterol-increasing effects of the CLASP1, LHX1, and SNTA1 loci and attenuate the LDL cholesterol-increasing effect of the CNTNAP2 locus. The CLASP1, LHX1, and SNTA1 regions harbor genes linked to muscle function and lipid metabolism. Our results elucidate the role of physical activity interactions in the genetic contribution to blood lipid levels
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Estimation of ocular volume from axial length
BACKGROUND/AIMS: To determine which biometric parameters provide optimum predictive power for ocular volume.
METHODS: Sixty-seven adult subjects were scanned with a Siemens 3-T MRI scanner. Mean spherical error (MSE) (D) was measured with a Shin-Nippon autorefractor and a Zeiss IOLMaster used to measure (mm) axial length (AL), anterior chamber depth (ACD) and corneal radius (CR). Total ocular volume (TOV) was calculated from T2-weighted MRIs (voxel size 1.0 mm(3)) using an automatic voxel counting and shading algorithm. Each MR slice was subsequently edited manually in the axial, sagittal and coronal plane, the latter enabling location of the posterior pole of the crystalline lens and partitioning of TOV into anterior (AV) and posterior volume (PV) regions.
RESULTS: Mean values (±SD) for MSE (D), AL (mm), ACD (mm) and CR (mm) were -2.62±3.83, 24.51±1.47, 3.55±0.34 and 7.75±0.28, respectively. Mean values (±SD) for TOV, AV and PV (mm(3)) were 8168.21±1141.86, 1099.40±139.24 and 7068.82±1134.05, respectively. TOV showed significant correlation with MSE, AL, PV (all p<0.001), CR (p=0.043) and ACD (p=0.024). Bar CR, the correlations were shown to be wholly attributable to variation in PV. Multiple linear regression indicated that the combination of AL and CR provided optimum R(2) values of 79.4% for TOV.
CONCLUSION: Clinically useful estimations of ocular volume can be obtained from measurement of AL and CR
Predictors of nurses’ and midwives’ intentions to provide maternal and child healthcare services to adolescents in South Africa
BACKGROUND: Adolescent mothers are at a much higher risk for maternal mortality compared to mothers aged
20 years and above. Newborns born to adolescent mothers are also more likely to have low birth weight, with the
risk of long-term effects such as early onset of adult diabetes than newborns of older mothers. Few studies have
investigated the determinants of adequate quality maternal and child healthcare services to pregnant adolescents.
This study was conducted to gain an understanding of nurses’ and midwives’ intentions to provide maternal and
child healthcare and family planning services to adolescents in South Africa.
METHODS: A total of 190 nurses and midwives completed a cross-sectional survey. The survey included components
on demographics, knowledge of maternal and child healthcare (MCH) and family planning (FP) services, attitude
towards family planning services, subjective norms regarding maternal and child healthcare and family planning
services, self-efficacy with maternal and child healthcare and family planning services, and intentions to provide
maternal and child healthcare and family planning services to adolescents. Pearson’s correlation analysis was
conducted to determine the association between knowledge, attitude, subjective norms, self-efficacy, and intention
variables for FP and MCH services. A 2-step linear regression analysis was then conducted for both FP and MCH
services to predict the intentions to provide FP and MCH services to adolescents.
RESULTS: Self-efficacy to conduct MCH services (β = 0.55, p < 0.01) and years of experience as a nurse- midwife
(β = 0.14, p < 0.05) were associated with stronger intentions to provide the services. Self-efficacy to provide FP
services (β = 0.30, p < 0.01) was associated with stronger intentions to provide FP services.
CONCLUSIONS: Self-efficacy has a strong and positive association with the intentions to provide both MCH and FP
services, while there is a moderate association with attitude and norms. There is a need to improve and strengthen
nurses’ and midwives’ self-efficacy in conducting both MCH and FP services in order to improve the quality and
utilization of the services by adolescents in South Africa.IS
Design Requirements for Inclusive Assistive Technologies: Facilitating Communication Between the Deaf and the Hearing
Communication plays a pivotal role in our society and, for many, relates to oral communication. Deaf people have always relied on sign-based communication and sign languages. However, for the last two centuries, they have been deprived of equal participation opportunities in a world designed for the Hearing. Targeting the communication barrier between the Deaf and the Hearing, this article aims to develop design requirements for an assistive technology that operates at the intersection between sign language and spoken language, facilitating communication at eye level. The opportunities provided by interdisciplinary development and new technological means allow us to envision a new generation of assistive technologies that foster inclusion instead of creating artificial hierarchies. We employ a Design Science Research approach incorporating a literature review, a web-content analysis, and interviews. We present 18 functional design requirements, eight UI and UX requirements, and nine requirements for the development process
Design Requirements for Inclusive Assistive Technologies: Facilitating Communication Between the Deaf and the Hearing
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