Phenomenology of TeV-scale scalar Leptoquarks in the EFT

We examine new aspects of leptoquark (LQ) phenomenology using effective field theory (EFT). We construct a complete set of leading effective operators involving SU(2) singlets scalar LQ and the SM fields up to dimension six. We show that, while the renormalizable LQ-lepton-quark interaction Lagrangian can address the persistent hints for physics beyond the Standard Model in the B-decays $\bar B \to D^{(*)} \tau \bar\nu$, $\bar B \to \bar K \ell^+ \ell^-$ and in the measured anomalous magnetic moment of the muon, the LQ higher dimensional effective operators may lead to new interesting effects associated with lepton number violation. These include the generation of one-loop sub-eV Majorana neutrino masses, mediation of neutrinoless double-$\beta$ decay and novel LQ collider signals. For the latter, we focus on 3rd generation LQ ($\phi_3$) in a framework with an approximate $Z_3$ generation symmetry, and show that one class of the dimension five LQ operators may give rise to a striking asymmetric same-charge $\phi_3 \phi_3$ pair-production signal, which leads to low background same-sign leptons signals at the LHC. For example, with $M_{\phi_3} \sim 1$ TeV and a new physics scale of $\Lambda \sim 5$ TeV, we expect about $5000$ positively charged $\tau^+ \tau^+$ events via $pp \to \phi_3 \phi_3 \to \tau^+ \tau^+ + 2 \cdot j_b$ ($j_b$=b-jet) at the 13 TeV LHC with an integrated luminosity of 300 fb$^{-1}$. It is interesting to note that, in the LQ EFT framework, the expected same-sign lepton signals have a rate which is several times larger than the QCD LQ-mediated opposite-sign leptons signals, $gg,q \bar q \to \phi_3 \phi_3^* \to \ell^+ \ell^- +X$. We also consider the same-sign charged lepton signals in the LQ EFT framework at higher energy hadron colliders such as a 27 TeV HE-LHC and a 100 TeV FCC-hh.Comment: 14 pages, 8 figures, final version as published in PR

Contextualising emotional well-being for conflict-affected populations: A study from the Thai-Myanmar Border

This paper examines the factors that migrant and displaced children from Myanmar consider essential to their emotional well-being. It underscores the importance of locally contextualised assessments of well-being and presents findings from a survey conducted across ten Migrant Learning Centres (MLCs) in Thailand to develop a framework identifying the positive and negative criteria of well-being that conflict-affected children prioritise in this context. In conducting such studies, actors working to support vulnerable groups can collect information to inform more effective and relevant responses to support children’s emotional well-being

Excitatory and inhibitory hippocampal neurons differ in their homeostatic adaptation to chronic M-channel modulation

A large body of studies has investigated bidirectional homeostatic plasticity both in vitro and in vivo using numerous pharmacological manipulations of activity or behavioral paradigms. However, these experiments rarely explored in the same cellular system the bidirectionality of the plasticity and simultaneously on excitatory and inhibitory neurons. M-channels are voltage-gated potassium channels that play a crucial role in regulating neuronal excitability and plasticity. In cultured hippocampal excitatory neurons, we previously showed that chronic exposure to the M-channel blocker XE991 leads to adaptative compensations, thereby triggering at different timescales intrinsic and synaptic homeostatic plasticity. This plastic adaptation barely occurs in hippocampal inhibitory neurons. In this study, we examined whether this homeostatic plasticity induced by M-channel inhibition was bidirectional by investigating the acute and chronic effects of the M-channel opener retigabine on hippocampal neuronal excitability. Acute retigabine exposure decreased excitability in both excitatory and inhibitory neurons. Chronic retigabine treatment triggered in excitatory neurons homeostatic adaptation of the threshold current and spontaneous firing rate at a time scale of 4–24 h. These plastic changes were accompanied by a substantial decrease in the M-current density and by a small, though significant, proximal relocation of Kv7.3-FGF14 segment along the axon initial segment. Thus, bidirectional homeostatic changes were observed in excitatory neurons though not symmetric in kinetics and mechanisms. Contrastingly, in inhibitory neurons, the compensatory changes in intrinsic excitability barely occurred after 48 h, while no homeostatic normalization of the spontaneous firing rate was observed. Our results indicate that excitatory and inhibitory hippocampal neurons differ in their adaptation to chronic alterations in neuronal excitability induced by M-channel bidirectional modulation

The Catechism for the use of all the churches of the French Empire. From its use by the good citizen‐soldier to its edition in Spain.

El presente artículo examina el catecismo impuesto por el emperador Napoleón I en 1806 para todos los territorios y estados aliados del Primer Imperio francés, el deterioro de las relaciones con la Iglesia católica, y los precedentes que se establecen desde la firma del Concordato de 1801. La distribución efectiva, y en grandes cantidades, de la nueva norma imperial permite al investigador acceder al catecismo en diversos idiomas y contextos. Este estudio expone la elaboración de la edición francesa y su traducción en 1807 gracias a Joaquín Antonio de Sojo. Será igualmente objeto de nuestro interés el uso de esta obra en la educación y su reflejo en el servicio militar. Para ello se emplearán los ejemplares en propiedad de la Biblioteca Histórica Marqués de Valdecilla.This article analyzes the catechism imposed by Emperor Napoleon I in 1806 for all the territories and allied states of the First French Empire, the deterioration of relations with the Catholic Church, and the precedents established since the signing of the Concordat of 1801. The effective and massive distribution of the new imperial norm allows the researcher to access it in various languages and contexts. In this study it will be exposed the elaboration of the French edition and its Spanish translation in 1807 thanks to Joaquín Antonio de Sojo. The use of this work in education and its reflection in military service will also be object of our interest. For this we will use the editions owned by the Marqués de Valdecilla Historical Library.Biblioteca Histórica Marqués de ValdecillaUCM. BibliotecaTRUEpu

El caso “Sonthonax”: ¿abolicionista o superviviente?

Contemporáneo de figuras tan icónicas como Jean-Jacques Dessalines y Toussaint Louverture, Léger-Félicité Sonthonax, natural de Oyonnax, ejerció de puente entre la asimilada población esclava del “pueblo de la alta montaña” (Haití) y la República francesa. Misionero de la paz, o representante de los intereses del “abolicionista” Jacques Pierre Brissot, el comisario galo proclamó la primera emancipación de los esclavos en el Caribe francés. Enfrentado a una población realista y mulata, Sonthonax desempeñó un papel crucial en las segunda y tercera comisiones civiles de Saint-Domingue. Retirado de sus funciones por el Consejo de los Quinientos, Léger-Félicité se vio atrapado entre el Consulado y el Imperio. La focalización de diversos ensayos sobre esta figura en su primera visita a la colonia en 1792 ha influido notablemente en un menor análisis de las restantes etapas de su larga travesía. El presente trabajo analiza los aspectos olvidados del diplomático Léger-Félicité Sonthonax en el marco de sus actividades en la isla y en territorio nacional. Asimismo, se pretende atenuar el nulo conocimiento de su obra en el mundo hispanohablante sobre la base de fuentes primarias