Risk awareness in secondary stroke prevention

Stroke is the single largest cause of disability and second highest cause of death globally. It is estimated that 10 million people a year are affected by stroke in the United Kingdom (UK). Of the 130,000 annual new stroke occurrences in the UK, one third will go on to have a further stroke. Recurrent stroke is more likely to be fatal than first stroke and survivors are more likely to be left with major disability. Many stroke patients do not adhere to secondary prevention strategies due to complex reasons, including lack of appreciation of their high risk of a secondary cardiovascular event. Long-term secondary prevention remains a desired goal in the management of stroke survivors, however, studies have shown that current strategies are not routinely and universally working. Hypothesis: Raising awareness of secondary stroke risk may improve stroke survivor’s adherence to secondary prevention strategies after stroke. Results: A survey of the general public (n=1019) and a population-based study of over 600 stroke survivors found that knowledge about Blood Pressure (BP) and stroke risk factors was poor in high risk populations. Only 55% of stroke survivors were able to cite any well-known vascular risk factors. However, those who were appropriately risk-aware significantly improved their health behaviour post-stroke by consuming less alcohol (P<0.001), less salt (P=0.05) and eating a healthy diet (P=0.02). Further, In a Randomised Controlled Trial setting an intervention to increase risk awareness was successful in increasing awareness (P=0.04) and resulted in a significant increase in knowledge of stroke sub-type (95% CI 0.72-0.677, P<0.001), risk factor control of systolic BP (95% CI 12.1-10.4, P=0.01) and increased the number of healthy lifestyle behaviour changes made at follow-up (P<0.001). Conclusions: Increasing risk awareness is potentially an important mechanism to improve health behaviour following stroke and may improve risk factor control as part of secondary stroke prevention

Nursing students' cultural beliefs and understanding of dementia: A phenomenological study across three continents

Background: Migrant nurses have reported difficulties adapting to their new culture and providing culturally sensitive care for people with dementia. However, to date no studies have explored the impact of student nurse's cultural heritage on their beliefs and understanding of dementia. Objectives: To explore the cultural beliefs of dementia of student nurses studying in England, Slovenia, Philippines and New Zealand. Design: An explorative hermeneutic phenomenology design. Settings: Higher Education Institutes delivering undergraduate nursing education in England (University of Greenwich and University of Essex), Slovenia (Angela Boškin Faculty of Health Care), New Zealand (University of Auckland), and the Philippines (University of Silliman). Participants: Student nurses studying nursing in England (n = 81), Slovenia (n = 41), Philippines (n = 53) and New Zealand (n = 6). Participants from England and New Zealand were from diverse cultural backgrounds. Student nurses at the beginning of their studies (n = 100) and towards the end of their studies (n = 81) participated. Methods: Completion of focus groups (n = 23), in England (n = 10), Slovenia (n = 6), Philippines (n = 6), and New Zealand (n = 1). All focus groups were audio recorded and transcribed verbatim. Data was analysed by applying an inductive theoretical approach of the Framework Method, which supports the generation of themes through open unhindered coding, pinpointing, examining, and recording patterns within the data. Results: Two major themes were identified in the data: familial piety and dementia discourse. Familial piety emerged from the importance of family and caring for family members with dementia, subthemes included: ‘my granddad’: familial experience, and ‘better to be with her’: familial home. Dementia discourse emerged from the terminology student nurses applied, such as: ‘preconceptions and misconceptions’ of aggression, and ‘considered crazy’ stigma of dementia due to a lack of awareness. Conclusions: The cultural heritage of student nurses impacted on their beliefs of dementia; however their understanding of the needs, care and support of a person with dementia changed and developed through clinical experience and education

Bio-Repository of DNA in stroke (BRAINS): A study protocol

<p>Abstract</p> <p>Background</p> <p>Stroke is one of the commonest causes of mortality in the world and anticipated to be an increasing burden to the developing world. Stroke has a genetic basis and identifying those genes may not only help us define the mechanisms that cause stroke but also identify novel therapeutic targets. However, large scale highly phenotyped DNA repositories are required in order for this to be achieved.</p> <p>Methods</p> <p>The proposed Bio-Repository of DNA in Stroke (BRAINS) will recruit all subtypes of stroke as well as controls from two different continents, Europe and Asia. Subjects recruited from the UK will include stroke patients of European ancestry as well as British South Asians. Stroke subjects from South Asia will be recruited from India and Sri Lanka. South Asian cases will also have control subjects recruited.</p> <p>Discussion</p> <p>We describe a study protocol to establish a large and highly characterized stroke biobank in those of European and South Asian descent. With different ethnic populations being recruited, BRAINS has the ability to compare and contrast genetic risk factors between those of differing ancestral descent as well as those who migrate into different environments.</p