1,564 research outputs found

    Costs and benefits of adapting to climate change at six meters below sea level

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    Climate change increases the vulnerability of low-lying coastal areas. Careful spatial planning can reduce this vulnerability. An assessment framework aimed at reducing vulnerability to climate change enables decision-makers to make better informed decisions about investments in adaptation to climate change through spatial planning. This paper presents and evaluates an approach to assess adaptation options, with the use of cost-benefit analysis

    Market Sampling of Landings of Commercial Fish Species in the Netherlands in 2002

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    This report contains information on the biological sampling for the market sampling program: which species are sampled, how they were caught, when and where the samples are taken (date and position), how many fish have been measured, how many fish have been aged, etc. The report gives an overview of all the biological sampling activities in 2002 by RIVO on the landings of the commercial important species of herring, mackerel, horse mackerel, blue whiting, greater argentine, sole, plaice, turbot, brill, dab, lemon sole, cod, whiting, Norway lobster and four different species of rays from all ICES areas. This biological sampling took place on landings by both the Dutch fleet as well as foreign fleets landing in the Netherlands. In addition this report contains information on the biological samples collected during research vessel surveys and discard trips both on commercial and non-commercial species

    Renormalization Group Study of the soliton mass on the (lambda Phi^4)_{1+1} lattice model

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    We compute, on the (λΦ4)1+1(\lambda \Phi^4)_{1+1} model on the lattice, the soliton mass by means of two very different numerical methods. First, we make use of a ``creation operator'' formalism, measuring the decay of a certain correlation function. On the other hand we measure the shift of the vacuum energy between the symmetric and the antiperiodic systems. The obtained results are fully compatible. We compute the continuum limit of the mass from the perturbative Renormalization Group equations. Special attention is paid to ensure that we are working on the scaling region, where physical quantities remain unchanged along any Renormalization Group Trajectory. We compare the continuum value of the soliton mass with its perturbative value up to one loop calculation. Both quantities show a quite satisfactory agreement. The first is slightly bigger than the perturbative one; this may be due to the contributions of higher order corrections.Comment: 19 pages, preprint DFTUZ/93/0

    Ultrafast quasiparticle relaxation dynamics in normal metals and heavy fermion materials

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    We present a detailed theoretical study of the ultrafast quasiparticle relaxation dynamics observed in normal metals and heavy fermion materials with femtosecond time-resolved optical pump-probe spectroscopy. For normal metals, a nonthermal electron distribution gives rise to a temperature (T) independent electron-phonon relaxation time at low temperatures, in contrast to the T^{-3}-divergent behavior predicted by the two-temperature model. For heavy fermion compounds, we find that the blocking of electron-phonon scattering for heavy electrons within the density-of-states peak near the Fermi energy is crucial to explain the rapid increase of the electron-phonon relaxation time below the Kondo temperature. We propose the hypothesis that the slower Fermi velocity compared to the sound velocity provides a natural blocking mechanism due to energy and momentum conservation laws.Comment: 10 pages, 11 figure

    Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production.

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    Loss of function of the insulin receptor (INSR) in humans produces severe insulin resistance. Unlike "common" insulin resistance, this is associated with elevated plasma levels of the insulin-sensitising, adipose-derived protein adiponectin. The underlying mechanism for this paradox is unclear, and it is at odds with the acute stimulation of adiponectin secretion reported on insulin treatment of cultured adipocytes. Given recent evidence for ligand-independent actions of the INSR, we used a lentiviral system to knock down Insr or its substrates Irs1 and Irs2 conditionally in 3T3-L1 murine preadipocytes/adipocytes to assess whether acute loss of their expression has different consequences to withdrawal of insulin. Efficient knockdown of either Insr or Irs1/2 was achieved by conditional shRNA expression, severely attenuating insulin-stimulated AKT phosphorylation and glucose uptake. Dual knockdown of Irs1 and Irs2 but not Insr in preadipocytes impaired differentiation to adipocytes. Acute knockdown of Insr or both Irs1 and Irs2 in adipocytes increased Adipoq mRNA expression but reduced adiponectin secretion, assessed by immunoassay. Knockdown sustained for 14 days also reduced immunoassay-detected adiponectin secretion, and moreover induced delipidation of the cells. These findings argue against a distinct effect of Insr deficiency to promote adiponectin secretion as the explanation for paradoxical insulin receptoropathy-related hyperadiponectinaemia.Adiponectin DELFIA assays were undertaken by the United Kingdom National Institute for Health Research (NIHR) Clinical Biochemistry Assay Laboratory. This work was supported by the Wellcome Trust (grant number WT098498), the Medical Research Council (MRC-MC-UU- 12012/5), and the NIHR Cambridge Biomedical Research Centre.This is the final version of the article. It first appeared from Nature Publishing Group via https://doi.org/10.1038/srep2110

    Catch comparison of pulse trawls vessels and a tickler chain beam trawler

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    Comparative fishing trials were conducted in May 2011 (week 19) on commercial beam trawlers fishing with conventional tickler chain beam trawls (on MFV GO4), pulse wings made by HFK-Engineering of Baarn, the Netherlands (MFV TX36), and pulse trawls produced by the DELMECO-Group of Goes, the Netherlands (version used on MFV TX68). The three vessels fished side-by-side as much as possible. Landings and discards of these vessels were monitored. Special emphasis was given on cod and whiting, that were dissected to study possible spinal damage. Result for TX36 and TX68 are expressed in terms of percentages of GO4. The pulse characteristics were as follows: TX36: voltage 45 V0 to peak, pulse frequency: 45 Hz, pulse duration 380 μs; electric power on single gear: 7.0 kW; TX68: voltage 50 V0 to peak, pulse frequency: 50 Hz, pulse duration 220 μs; electric power on single gear: 8.5 kW. The fuel consumption recorded over the whole week was considerably lower for the pulse trawls, i.e. on TX36 (40%) and on TX68 (54%), than for the tickler chain beam trawls used on the GO4. The net earnings (taken as gross earnings minus fuel costs) for the TX36 were almost twice as large at 186%, and for the TX68 also considerably higher at 155%. The vessels with pulse trawls caught fewer (65-69%) target species, but also less (30-50%) immature and non-target fish ('discards'), and benthic species (48-73%) than the vessel with tickler chains on these fishing grounds and in this period. The pulse gears caught fewer (19-42%) kg per hour cod than the tickler chain beam trawls, but the catches of cod on all three vessels were very small. For plaice and dab these differences were statistically proven, for brill, turbot and cod this was not the case. There was no marked difference between both pulse trawl vessels in total landings. The TX68 caught less marketable sole, but not significantly less undersized sole than the GO4. The TX36 caught less undersized sole, but here the difference in marketable fish was not significant. Catches of brill and turbot were so small that no statistically substantiated conclusion could be drawn. Only for undersized turbot the TX36 caught less. For whiting we found a demonstrable reduction in both marketable and undersized fish in both pulse fishing vessels. The TX36 caught less whiting in number per hour. The CPUEs found from the auction data and the sampled hauls correlated reasonably well for the most abundant species, such as plaice and sole. However, for less abundant species the results did not match very well, and care should be taken to increase the sampling rate in future comparative fishing studies. Spinal fracture in cod occurred under pulse stimulation but to a limited extent in both marketable and undersized fish. There is an indication that this happens slightly more on TX68 (11%) than on TX36 (7%). Whiting hardly seems to suffer any damage

    Ultrafast dynamics of coherent optical phonons and nonequilibrium electrons in transition metals

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    The femtosecond optical pump-probe technique was used to study dynamics of photoexcited electrons and coherent optical phonons in transition metals Zn and Cd as a function of temperature and excitation level. The optical response in time domain is well fitted by linear combination of a damped harmonic oscillation because of excitation of coherent E2gE_{2g} phonon and a subpicosecond transient response due to electron-phonon thermalization. The electron-phonon thermalization time monotonically increases with temperature, consistent with the thermomodulation scenario, where at high temperatures the system can be well explained by the two-temperature model, while below \approx 50 K the nonthermal electron model needs to be applied. As the lattice temperature increases, the damping of the coherent E2gE_{2g} phonon increases, while the amplitudes of both fast electronic response and the coherent E2gE_{2g} phonon decrease. The temperature dependence of the damping of the E2gE_{2g} phonon indicates that population decay of the coherent optical phonon due to anharmonic phonon-phonon coupling dominates the decay process. We present a model that accounts for the observed temperature dependence of the amplitude assuming the photoinduced absorption mechanism, where the signal amplitude is proportional to the photoinduced change in the quasiparticle density. The result that the amplitude of the E2gE_{2g} phonon follows the temperature dependence of the amplitude of the fast electronic transient indicates that under the resonant condition both electronic and phononic responses are proportional to the change in the dielectric function.Comment: 10 pages, 9 figures, to appear in Physical Review

    Vitamin D deficiency as a risk factor for infection, sepsis and mortality in the critically ill: systematic review and meta-analysis

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    INTRODUCTION: In Europe, vitamin D deficiency is highly prevalent varying between 40% and 60% in the healthy general adult population. The consequences of vitamin D deficiency for sepsis and outcome in critically ill patients remain controversial. We therefore systematically reviewed observational cohort studies on vitamin D deficiency in the intensive care unit.METHODS: Fourteen observational reports published from January 2000 to March 2014, retrieved from Pubmed and Embase, involving 9,715 critically ill patients and serum 25-hydroxyvitamin D3 (25 (OH)-D) concentrations, were meta-analysed.RESULTS: Levels of 25 (OH)-D less than 50 nmol/L were associated with increased rates of infection (risk ratio (RR) 1.49, 95% (confidence interval (CI) 1.12 to 1.99), P = 0.007), sepsis (RR 1.46, 95% (CI 1.27 to 1.68), P <0.001), 30-day mortality (RR 1.42, 95% (CI 1.00 to 2.02), P = 0.05), and in-hospital mortality (RR 1.79, 95% (CI 1.49 to 2.16), P <0.001). In a subgroup analysis of adjusted data including vitamin D deficiency as a risk factor for 30-day mortality the pooled RR was 1.76 (95% CI 1.37 to 2.26, P <0.001).CONCLUSIONS: This meta-analysis suggests that vitamin D deficiency increases susceptibility for severe infections and mortality of the critically ill
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