NCBI’s virus discovery codeathon: building “FIVE” —the Federated Index of Viral Experiments API index

Viruses represent important test cases for data federation due to their genome size and the rapid increase in sequence data in publicly available databases. However, some consequences of previously decentralized (unfederated) data are lack of consensus or comparisons between feature annotations. Unifying or displaying alternative annotations should be a priority both for communities with robust entry representation and for nascent communities with burgeoning data sources. To this end, during this three-day continuation of the Virus Hunting Toolkit codeathon series (VHT-2), a new integrated and federated viral index was elaborated. This Federated Index of Viral Experiments (FIVE) integrates pre-existing and novel functional and taxonomy annotations and virus–host pairings. Variability in the context of viral genomic diversity is often overlooked in virus databases. As a proof-of-concept, FIVE was the first attempt to include viral genome variation for HIV, the most well-studied human pathogen, through viral genome diversity graphs. As per the publication of this manuscript, FIVE is the first implementation of a virus-specific federated index of such scope. FIVE is coded in BigQuery for optimal access of large quantities of data and is publicly accessible. Many projects of database or index federation fail to provide easier alternatives to access or query information. To this end, a Python API query system was developed to enhance the accessibility of FIVE

Privatization in Western Europe: Stylized Facts, Outcomes, and Open Issues

Privatization has certainly been one of the main events of the economic and financial history of the 20th century. Between 1997 and 2004 more than 4,000 privatization operations were carried out in the world, bringing to governments revenues for over 1,350US$billion. Western Europe emerges as the most important region, having implemented the greatest number of privatizations and raised a half of global revenues. The relevance of Western Europe in the process can be ascribed to several factors. This paper investigates the causes of this process, summarizes the main trends of privatization activity at the country level, analyzes the main privatization drivers and provides an account of the main findings of the effects of privatization at the macro and microeconomic level

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Some Studies of Asymmetric Dipole Antenna with Arbitrarily Displaced Feed-points Immersed in Weakly Ionized Plasma

234-239A theoretical study of radiation of electromagnetic and electroacoustic waves from an asymmetric dipole antenna with arbitrarily displaced feed-points immersed in an infinite, lossy, compressible, weakly-ionized plasma bas been made. It is shown that the propagation is almost unaffected by plasma when source frequencies much higher than the plasma frequency are used. However, if the source of radiation is operated at frequencies lower than the plasma frequency, the plasma medium is found to have its profound effect on the radiation. General expressions for the far-field radiation pattern are developed for both electromagnetic and electroacoustic modes. The arbitrarily displaced system has been studied under three different configurations, namely, the arbitrary di8placement, transverse displacement and the axial displacement for various values of feed-point displacement (2R/λ). Theoretical radiation patterns for the above mentioned configurations have been obtained for the source frequency much greater than the plasma frequency for the electromagnetic mode

The dispositional antecedents of promotive and prohibitive voice.

We propose that promotive voice, or the expression of suggestions for improving work practices in the organization, and prohibitive voice, or the expression of warnings about factors that can harm the organization, are differentially influenced by employees' dispositional inclination to be approach and avoidance oriented. Drawing on multisource survey data from 291 employees and their managers, we found that approach orientation had positive relationship with promotive voice and negative relationship with prohibitive voice. By contrast, avoidance orientation had positive relationship with prohibitive voice and negative relationship with promotive voice. Further, voice role expectations, or employees' beliefs about the extent to which a particular form of voice is expected from them in their daily work, moderated the effects of approach and avoidance orientations. Highlighting the unique nature of voice as a behavior that is especially sensitive to situational cues, the effects of approach and avoidance orientations on promotive and prohibitive voice were stronger when role expectations for that form of voice were weaker. The theoretical implications of these findings are discussed. (PsycINFO Database Recor