Role of Oxidative/Nitrosative Stress in Diarrhea and Constipation

Oxidative/nitrosative stress, a pervasive condition of increased amounts of reactive and nitrogen species, is responsible for a variety of degenerative processes in some human diseases such as gastrointestinal affections. Diarrhea is one such infection that has long been recognized as one of the most important health problems in developing countries. Constipation is a delay or difficulty in evacuating the stool. In this respect, several studies were performed and have shown that the diarrhea pathophysiology and constipation were accompanied by accumulation of biomarkers of oxidative/nitrosative stress as well as the depletion of antioxidant system. In this chapter, we discuss about the recent advances that propose a major role of oxidative/nitrosative stress on diarrhea pathogenesis and constipation

Modulating and opposite actions of two aqueous extracts prepared from<i>Cinnamomum cassia</i>L. bark and<i>Quercus ilex</i>L. on the gastrointestinal tract in rats

Cinnamon bark and evergreen oak acorns, natural sources of functional ingredients, are effective for those suffering from diarrhea, constipation and irritable bowel syndrome.</p

The potential of <i>Thymus vulgaris</i> aqueous extract to protect against delayed gastric emptying and colonic constipation in rats

Thyme is a rich source of bioactive phytochemicals and it is frequently used in folk-medicine to treat gastroenteritis irritations.</p