157 research outputs found
GREEK COASTAL MIRES: A PRELIMINARY STUDY OF THE AGOULINITSA PEATLAND, WESTERN PELOPONNESE
Ο τυρφώνας της Αγουλινίτσας σχηματίστηκε στη δυτική ακτή της ομώνυμης λίμνης, η οποία αποξηράνθηκε το 1969, εξαιτίας της αυξανόμενης ζήτησης για καλλιεργήσιμες εκτάσεις. Η παρούσα μελέτη αποτελεί μια πρώτη προσπάθεια για τη διερεύνηση των συνθηκών που επικρατούσαν κατά την τυρφογένεση. Για τις ανάγκες της μελέτης πραγματοποιήθηκαν διατρήματα μικρού βάθους, καθώς και προσδιορισμοί των φυσικών, χημικών ιδιοτήτων της τύρφης, και των ορυκτολογικών συστατικών της. Η υψηλή περιεκτικότητα σε τέφρα και οι υψηλές τιμές του pH υποδηλώνουν πως η τύρφη σχηματίστηκε κάτω από αλκαλικές συνθήκες, ενώ οι υψηλές τιμές της ηλεκτρικής αγωγιμότητας υποδηλώνουν έντονη τροφοδοσία με διαλυμένα στερεά. Στην τύρφη προσδιορίστηκαν αργιλικά ορυκτά, χαλαζίας, ασβεστίτης, αλίτης, συλβίτης και σιδηροπυρίτης. Η κατανομή των παραπάνω ορυκτών με το βάθος υποδηλώνει την επικράτηση συνθηκών γλυκού νερού κατά το μεγαλύτερο διάστημα απόθεσης της τύρφης στο κεντρικό τμήμα της περιοχής, ενώ στο νότιο τμήμα η επίδραση της θάλασσας ήταν πιο έντονη και οι συνθήκες χαρακτηρίζονται ως ελαφρά υφάλμυρες. Συμπερασματικά ο τυρφώνας της Αγουλινίτσας μπορεί να χαρακτηριστεί ως ένας τυρφώνας που σχηματίστηκε πίσω από αμμώδεις φραγμούς. Παρόμοιες συνθήκες κυριαρχούσαν ήδη από το Νεογενές, στις δυτικές ακτές της Πελοποννήσου και ευνόησαν τη γένεση λιγνιτικών κοιτασμάτων στην ευρύτερη περιοχήThe Agoulinitsa peatland formed on the western shore of the homonymous lake, which was drained in 1969 because of the emerging demand for agricultural land. This study is a preliminary attempt to determine the conditions that prevailed during peat formation. Shallow cores were obtained from the peatland and initial physical, chemical and mineralogical analyses were carried out. High ash yield and pH values indicate that peat accumulated under alkaline conditions with periods of high clastic material influx, while high electric conductivity values indicate increased influx of dissolved solids into the mire. The mineral matter consists mainly of clay minerals, quartz, calcite, halite, sylvite and pyrite. The distribution of these minerals with depth indicates that fresh-water conditions prevailed for a long period during peat accumulation at the central part of the peatland, whereas the sea-water influence was more intense to the south establishing slightly brackish conditions. All data suggest that the Agoulinitsa peatland was developed as a back-barrier mire formed at the southwestern part of the Agoulinitsa Lake, and hence it can be considered as a modern analogue of the Neogene lignite deposits occurring along the west coast of Péloponnès
EARLY STAGES OF LIGNITE FORMATION IN PTOLEMAIS BASIN: A COAL-PETROGRAPHIC APPROACH
With the present study it is intended to assess the depositional palaeoenvironment of the lower part of the Lignite-bearing Sequence in the Ptolemais Basin, and more specifically in the areas of Notio-Field and Tomeas-6 open pits. The sediments under study represent the seam between the Volcanic Tephra Layer and the Basal Marl, which constitute the roof and the floor, respectively. Coal-petrographic results showed that Huminite is the main macerai group (84-96%), while macérais from Liptinite and Inertinite groups display low values (<10%). In bulk lignite samples the main mineral phases are quartz, calcite, clay minerals and feldspars, while in the ashes the main phases are quartz, anhydrite and lime. The palaeoenvironment of the lignite formation was reconstructed using the lithological, coalpetrographic and mineralogical data, as well as coal-facies diagrammes. In Notio-Field Mine, at the early stages of lignite formation the conditions used to be limnotelmatic, while in Tomeas-6 Mine they were telmatic. Upwards the conditions turned to more telmatic in both mine areas. The vegetation was mainly herbaceous with some arboreal elements occurring mostly in Tomeas-6 area. The water influx was generally intense resulting in enhanced inorganic inpu
EARLY STAGES OF LIGNITE FORMATION IN PTOLEMAIS BASIN: A COAL-PETROGRAPHIC APPROACH
With the present study it is intended to assess the depositional palaeoenvironment of the lower part of the Lignite-bearing Sequence in the Ptolemais Basin, and more specifically in the areas of Notio-Field and Tomeas-6 open pits. The sediments under study represent the seam between the Volcanic Tephra Layer and the Basal Marl, which constitute the roof and the floor, respectively. Coal-petrographic results showed that Huminite is the main macerai group (84-96%), while macérais from Liptinite and Inertinite groups display low values (<10%). In bulk lignite samples the main mineral phases are quartz, calcite, clay minerals and feldspars, while in the ashes the main phases are quartz, anhydrite and lime. The palaeoenvironment of the lignite formation was reconstructed using the lithological, coalpetrographic and mineralogical data, as well as coal-facies diagrammes. In Notio-Field Mine, at the early stages of lignite formation the conditions used to be limnotelmatic, while in Tomeas-6 Mine they were telmatic. Upwards the conditions turned to more telmatic in both mine areas. The vegetation was mainly herbaceous with some arboreal elements occurring mostly in Tomeas-6 area. The water influx was generally intense resulting in enhanced inorganic inpu
Ethnic differences in the association between blood pressure components and chronic kidney disease in middle aged and older Asian adults
10.1186/1471-2369-14-86BMC Nephrology141
The effects of the addition of losartan on uric acid metabolism in patients receiving indapamide
OBJECTIVE: A number of adverse metabolic effects are associated with indapamide administration, including an increase in serum uric acid levels. It has been reported that losartan can significantly decrease serum uric acid levels. However, there are no data on the effects of combination therapy of losartan with indapamide on uric acid metabolism. METHODS: We studied 20 hypertensive patients in whom serum metabolic parameters, including uric acid levels in serum and urine, were studied before and after eight weeks of indapamide administration (2.5 mg once daily) as well as eight weeks after combination treatment with indapamide (2.5 mg once daily)and losartan (50 mg/day). RESULTS: Indapamide evoked a significant decrease in systolic and diastolic blood pressure from a mean value of 157 +/- 12 mmHg/96 +/- 10 mmHg to a mean value of 139 +/- 14 mmHg/92 +/- 5 mmHg (p<0.01 for both comparisons). However, a significant increase in serum uric acid levels was noticed after indapamide administration (from a mean value of 4.9 +/- 1.6 mg/dl to a mean value of 5.9 +/- 1.2 mg/dl, p<0.01), associated with a decrease in the fractional excretion of uric acid(from a mean value of 9 +/- 5% to a mean value of 7 +/- 5.5%, p<0.05). The addition of losartan caused a further decrease in blood pressure from a mean value of 139 +/- 14 mmHg/92 +/- 5 mmHg to a mean value of 120 +/- 15 mmHg/84 +/- 4 mmHg (p<0.01 for both comparisons). This was followed by a significant decrease in serum uric acid levels to 5 +/- 1.1 mg/dl(p<0.01) due to a substantial increase in fractional urate excretion (from 7 +/- 5.5 to 8.7 +/- 6%, p<0.05). CONCLUSION: The addition of losartan could offset the hyperuricaemic effect of indapamide administration.J Renin Angiotensin Aldosterone Sys
Using CIPP model to evaluate “NTUE 2012 Nepal Snowland school” service-learning project
In 2012, the department of Education, National Taipei University of Education (NTUE), conducted an oversea service-learning project to Nepal. The project was tied with two courses, i.e., Service-Learning Theory and Practice as well as International Education research. There were 9 university students (volunteer teachers) and 4 professors in the NTUE delegation. They served the 150 students of Snowland Ranag Light of Education School at Kathmandu, Nepal. This study aimed to use the CIPP model to evaluate the context, input, process and product of the project. Classroom observations, interviews questionnaires and document analysis were used to collect data following the triangulation principle. The research findings were as follows. 1. The context of the NTUE Nepal service-learning project includes the impact of low birth rate to NTUE, the high demand of international education in Taiwan, and the enhancement of pre- and in-service teacher’s affective domain. 2. The inputs include internal and external human resources in Taiwan and Nepal, funds from government and university, donated supplies collected by students. 3. The process includes the five phases of service-learning, with preparation from October, 2011 to August, 2012; service in the first two weeks of September, 2012; series of celebration activities in mid September at Snowland and autumn at NTUE; while reflection and evaluation phases throughout the entire process. 4. The product was evaluated according to the three instructional objectives, i.e., (1) to learn about Nepali culture and education, (2) to be able to teach Nepali 4th to 9th grade students mandarin Chinese and Taiwanese culture in English, and (3) to demonstrate affection to Snowland or Nepal. Based on the findings, recommendations were made to future practice and research
Flow-Cytometric Phosphoprotein Analysis Reveals Agonist and Temporal Differences in Responses of Murine Hematopoietic Stem/Progenitor Cells
Hematopoietic stem cells (HSCs) are probably the best-studied adult tissue-restricted stem cells. Although methods for flow cytometric detection of phosphoproteins in hematopoeitic progenitors and mature cells are available, analogous protocols for HSC are lacking. We present a robust method to study intracellular signaling in immunophenotypically-defined murine HSC/progenitor cell (HPC)-enriched populations. Using this method, we uncover differences in the response dynamics of several phosphoproteins representative of the Ras/MAP-Kinase(K), PI3K, mTOR and Jak/STAT pathways in HSC/HPCs stimulated by Scf, Thpo, as well as several other important HSC/HPC agonists
Suboptimal blood pressure control in chronic kidney disease stage 3: baseline data from a cohort study in primary care
BACKGROUND: Poorly controlled hypertension is independently associated with mortality, cardiovascular risk and disease progression in chronic kidney disease (CKD). In the UK, CKD stage 3 is principally managed in primary care, including blood pressure (BP) management. Controlling BP is key to improving outcomes in CKD. This study aimed to investigate associations of BP control in people with CKD stage 3. METHODS: 1,741 patients with CKD 3 recruited from 32 general practices for the Renal Risk in Derby Study underwent medical history, clinical assessment and biochemistry testing. BP control was assessed by three standards: National Institute for Health and Clinical Excellence (NICE), National Kidney Foundation Kidney Disease Outcome Quality Initiative (KDOQI) and Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. Descriptive statistics were used to compare characteristics of people achieving and not achieving BP control. Univariate and multivariate logistic regression was used to identify factors associated with BP control. RESULTS: The prevalence of hypertension was 88%. Among people with hypertension, 829/1426 (58.1%) achieved NICE BP targets, 512/1426 (35.9%) KDOQI targets and 859/1426 (60.2%) KDIGO targets. Smaller proportions of people with diabetes and/or albuminuria achieved hypertension targets. 615/1426 (43.1%) were only taking one antihypertensive agent. On multivariable analysis, BP control (NICE and KDIGO) was negatively associated with age (NICE odds ratio (OR) 0.27; 95% confidence interval (95% CI) 0.17-0.43) 70–79 compared to <60), diabetes (OR 0.32; 95% CI 0.25-0.43)), and albuminuria (OR 0.56; 95% CI 0.42-0.74)). For the KDOQI target, there was also association with males (OR 0.76; 95% CI 0.60-0.96)) but not diabetes (target not diabetes specific). Older people were less likely to achieve systolic targets (NICE target OR 0.17 (95% CI 0.09,0.32) p < 0.001) and more likely to achieve diastolic targets (OR 2.35 (95% CI 1.11,4.96) p < 0.001) for people >80 compared to < 60). CONCLUSIONS: Suboptimal BP control was common in CKD patients with hypertension in this study, particularly those at highest risk of adverse outcomes due to diabetes and or albuminuria. This study suggests there is scope for improving BP control in people with CKD by using more antihypertensive agents in combination while considering issues of adherence and potential side effects
Decreased renal function in overweight and obese prepubertal children
BACKGROUND: Obesity is a potentially modifiable risk factor for the development and progression of kidney disease, both in adults and children. We aim to study the association of obesity and renal function in children, by comparing estimated glomerular filtration rate (eGFR) in nonoverweight and overweight/obese children. Secondarily, we aim to evaluate the accuracy of equations on eGFR estimation when compared to 24-h urinary creatinine clearance (CrCl).
METHODS: Cross-sectional study of 313 children aged 8-9 y, followed in the birth cohort Generation XXI (Portugal). Creatinine and cystatin C, GFR estimated by several formulas and CrCl were compared in 163 nonoverweight and 150 overweight/obese, according to World Health Organization growth reference.
RESULTS: Overweight/obese children had significantly lower eGFR, estimated by all methods, except for CrCl and revised Schwartz formula. Despite all children having renal function in the normal range, eGFR decreased significantly with BMI z-score (differences ranging from -4.3 to -1.1 ml/min/1.73 m(2) per standard deviation of BMI). The Zappitelli combined formula presented the closest performance to CrCl, with higher correlation coefficients and higher accuracy values.
CONCLUSION: Young prepubertal children with overweight/obesity already present significantly lower GFR estimations that likely represent some degree of renal impairment associated with the complex deleterious effects of adiposity
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