414 research outputs found

    Discovery of Yttrium, Zirconium, Niobium, Technetium, and Ruthenium Isotopes

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    Currently, thirty-four yttrium, thirty-five zirconium, thirty-four niobium, thirty-five technetium, and thirty-eight ruthenium isotopes have been observed and the discovery of these isotopes is discussed here. For each isotope a brief synopsis of the first refereed publication, including the production and identification method, is presented.Comment: To be published in Atomic Data and Nuclear Data Table

    Discovery of palladium, antimony, tellurium, iodine, and xenon isotopes

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    Currently, thirty-eight palladium, thirty-eight antimony, thirty-nine tellurium, thirty-eight iodine, and forty xenon isotopes have been observed and the discovery of these isotopes is discussed here. For each isotope a brief synopsis of the first refereed publication, including the production and identification method, is presented.Comment: to be published in At. Data Nucl. Data Table

    Discovery of the Isotopes with 11 <= Z <= 19

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    A total of 194 isotopes with 11 \le Z \le 19 have been identified to date. The discovery of these isotopes which includes the observation of unbound nuclei, is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.Comment: to be pubslihed in At. Data Nucl. Data Table

    Study of the 93-Nb + 7-Li Reactions with Application to Double Charge Exchange and Possible Production of New Neutron-Rich Nuclei

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    Supported by the National Science Foundation and Indiana Universit

    Study of the 93-Nb+7-Li Reactions with Application to Double Charge Exchange and Possible Production of Neutron-Rich Nuclei

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    This work was supported by the National Science Foundation Grant NSF PHY 78-22774 A02 & A03 and by Indiana Universit

    Improving route optimization for outbound vehicle distribution at an automobile manufacturer

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    Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management; and, (S.M.)--Massachusetts Institute of Technology, Engineering Systems Division; in conjunction with the Leaders for Global Operations Program at MIT, September 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p. 78-79).With rising fuel costs and increasing rates among specialized shipping carriers, cost mitigation in outbound distribution is increasingly important for automobile manufacturers. Many manufacturers have turned to specialized, licensed supply chain software to optimize their distribution network to determine the appropriate path for each product from factory to dealer. While these software programs include robust algorithms for optimizing the network, they are only as strong as the user inputs. To gain maximum value from supply chain software, automotive companies must fully understand the structure of their networks, their costs, and their constraints to ensure that the model is all-inclusive. This paper attempts to understand the distribution model used at Nissan North America by formulating the model algebraically with a linear program. With insights to the model design, we uncover several opportunities for improvement. Specifically, we create a more inclusive objective function by ensuring that all relevant costs are captured so that the model optimizes the "total landed cost." We also highlight several opportunities for increased model flexibility in areas where the model is over constrained -- both in its mathematical constraints and in its structural design. With increased flexibility, supply chain software has more alternative paths in the network to choose from, increasing the opportunity for the program to find a lower cost solution. Lastly, we stress the importance of using the software for scenario analysis to create a more responsive supply chain. When implemented, the improvements presented in this paper yield a cost savings of over $10 million. The principles of the model improvements in this thesis can be applied to distribution optimization in any industry.by Elizabeth Katcoff.S.M.M.B.A

    A day care center in color.

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    Thesis. 1976. M.Arch.--Massachusetts Institute of Technology. Dept. of Architecture.Microfiche copy available in Archives and Rotch.Bibliography: leaves 53-54.M.Arch

    Nuclear distribution of porphobilinogen deaminase (PBGD) in glioma cells: a regulatory role in cancer transformation?

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    Recently, considerable interest has been directed to red-fluorescence photodiagnosis of brain and other tumours during surgery using the protoporphyrin IX natural precursor, 5-aminolaevulinic acid. In the present study we focused on the role of the rate-limiting enzyme porphobilinogen deaminase in glioma C6 cell activity, differentiation and sub-cellular distribution. Over-expression of the human housekeeping porphobilinogen deaminase in the glioma cells, using the housekeeping-porphobilinogen deaminase plasmid, induced a G1 cell cycle attenuation accompanied by increases in enzyme activity and c6 differentiation toward astrocytes. Visualisation of subcellular localisation of the porphobilinogen deaminase using the independent techniques of fluorescence immuno-staining with specific anti-human porphobilinogen deaminase antibodies and cellular expression of porphobilinogen deaminase fused to green fluorescent protein, revealed (unexpectedly) a major fraction of porphobilinogen deaminase in the nucleus and only a minor fraction in the cytoplasm. Both C and N terminals of porphobilinogen deaminase fused to green fluorescent protein revealed a major fraction of the newly synthesized fused porphobilinogen deaminase in the nucleus. Furthermore, newborn rat brain cells grown in a primary culture showed the same localisation pattern of porphobilinogen deaminase in the nuclei. Stimulation of C6 glioma cell differentiation by butyrate induced a marked decrease in porphobilinogen deaminase both in the nucleus and in the cytoplasm as determined by Western blotting and fluorescence immuno-localisation. These findings suggest a possible dual role for housekeeping porphobilinogen deaminase in fast dividing glioma cells, one related to the porphyrin synthesis pathway and another coupled to nuclear function, which might be linked to tumorigenesis

    The emission of K-X-rays in slow neutron fission of 233U, 235U, and 239Pu

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32893/1/0000272.pd
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