62,500 research outputs found
Gas Dynamics of the Nickel-56 Decay Heating in Pair-Instability Supernovae
Very massive 140-260 Msun stars can die as highly-energetic pair-instability
supernovae (PI SNe) with energies of up to 100 times those of core-collapse SNe
that can completely destroy the star, leaving no compact remnant behind. These
explosions can synthesize Msun of radioactive Ni56, which can cause
them to rebrighten at later times when photons due to Ni56 decay diffuse out of
the ejecta. However, heat from the decay of such large masses of Ni56 could
also drive important dynamical effects deep in the ejecta that are capable of
mixing elements and affecting the observational signatures of these events. We
have now investigated the dynamical effect of Ni56 heating on PI SN ejecta with
high-resolution two-dimensional hydrodynamic simulations performed with the
CASTRO code. We find that expansion of the hot Ni56 bubble forms a shell at the
base of the silicon layer of the ejecta about 200 days after the explosion but
that no hydrodynamical instabilities develop that would mix Ni56 with the
Si/O-rich ejecta. However, while the dynamical effects of Ni56 heating may be
weak they could affect the observational signatures of some PI SNe by diverting
decay energy into internal expansion of the ejecta at the expense of
rebrightening at later times.Comment: Accepted to ApJ, 14 page
Shot noise in magnetic tunnel junctions from first principles
We compute the shot noise in ballistic and disordered Fe/MgO/Fe tunnel
junctions by a wave function-matching method. For tunnel barriers with no more
than 5 atomic layers we find a suppression of the Fano factor as a function of
the magnetic configuration. For thicker MgO barriers the shot noise is
suppressed up to a threshold bias indicating the onset of resonant tunneling.
We find excellent agreement with recent experiments when interface disorder is
taken into accountComment: 5 pages,5 figure
Flow in small and large quark-gluon plasma droplets: the role of nucleon substructure
We study the effects of nucleon substructure on bulk observables in
proton-lead collisions at the LHC using Bayesian methodology. Substructure is
added to the TRENTO parametric initial condition model using Gaussian nucleons
with a variable number of Gaussian partons. We vary the number and width of
these partons while recovering the desired inelastic proton-proton cross
section and ensemble averaged proton density. We then run the model through a
large number of minimum bias hydrodynamic simulations and measure the response
of final particle production and azimuthal particle correlations to initial
state properties. Once these response functions are determined, we calibrate
free parameters of the model using established Bayesian methodology. We comment
on the implied viability of the partonic model for describing hydrodynamic
behavior in small systems.Comment: proceedings for Quark Matter 201
Direct reconstruction of dynamical dark energy from observational Hubble parameter data
Reconstructing the evolution history of the dark energy equation of state
parameter directly from observational data is highly valuable in
cosmology, since it contains substantial clues in understanding the nature of
the accelerated expansion of the Universe. Many works have focused on
reconstructing using Type Ia supernova data, however, only a few studies
pay attention to Hubble parameter data. In the present work, we explore the
merit of Hubble parameter data and make an attempt to reconstruct from
them through the principle component analysis approach. We find that current
Hubble parameter data perform well in reconstructing ; though, when
compared to supernova data, the data are scant and their quality is worse. Both
CDM and evolving models can be constrained within at
redshifts
and even at redshifts 0.1 z 1 by
using simulated data of observational quality.Comment: 25 pages, 11 figure
Thermal spin-transfer in Fe-MgO-Fe tunnel junctions
We compute thermal spin transfer torques (TST) in Fe-MgO-Fe tunnel junctions
using a first principles wave function-matching method. At room temperature,
the TST in a junction with 3 MgO monolayers amounts to 10^-7J/m^2/K, which is
estimated to cause magnetization reversal for temperature differences over the
barrier of the order of 10 K. The large TST can be explained by multiple
scattering between interface states through ultrathin barriers. The angular
dependence of the TST can be very skewed, possibly leading to thermally induced
high-frequency generation.Comment: 5 pages, 5 figure
Body composition, IGF1 status, and physical functionality in nonagenarians: implications for osteosarcopenia
OBJECTIVES:
Body composition alterations occur during aging. The purpose of the present analysis was to explore the functional consequences of the overlap of sarcopenia and osteoporosis, and the potential role of insulin-like growth factor 1 (IGF1) in their development in the oldest old.
SETTING AND PARTICIPANTS:
Eighty-seven nonagenarians from the Louisiana Healthy Aging Study were included.
MEASURES:
The definition of sarcopenia was based on appendicular lean mass (ALM). Osteoporosis was diagnosed based on bone mineral density (BMD) T score. Four phenotypes were compared: (1) healthy body composition, that is, nonosteoporotic nonsarcopenic (CO, control group), (2) osteoporotic (O, low BMD T score), (3) sarcopenic (S, low ALM), and (4) osteosarcopenic (OS, low BMD T score and low ALM). Sex- and age-specific IGF1-Standard Deviation Scores (SDS) were calculated. The Continuous Scale-Physical Functional Performance (CS-PFP) test was performed.
RESULTS:
In OS men, IGF1-SDS values (-0.61 ±0.37 vs -0.04 ± 0.52, P = .02) were lower than those in CO males (control group), whereas IGF1-SDS were similar in the 4 body composition phenotypes in women. In men only, ALM was positively associated with IGF1-SDS values (P = .01) independent of age and C-reactive protein concentration. Regarding bone health, we found no association between IGF1-SDS values and BMD. IGF1-SDS was not associated with functional performance (CS-PFP) in men and women.
CONCLUSIONS/IMPLICATIONS:
IGF1 sensitivity in skeletal muscle and bone may differ by sex in the oldest old. IGF1 status did not appear to affect physical functionality. Determinants and clinical and functional characteristics of osteosarcopenia need to be further investigated in order to define conclusive diagnostic criteria
Spin Dependence of Interfacial Reflection Phase Shift at Cu/Co Interface
The spin dependent reflection at the interface is the key element to
understand the spin transport. By completely solving the scattering problem
based on first principles method, we obtained the spin resolved reflectivity
spectra. The comparison of our theoretical results with experiment is good in a
large energy scale from Fermi level to energy above vacuum level. It is found
that interfacial distortion is crucial for understanding the spin dependence of
the phase gain at the CuCo interface. Near the Fermi level, image state
plays an important role to the phase accumulation in the copper film.Comment: 6 papges, 3 figures, accepted by Physical Review
RNA-seq transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis
Bovine tuberculosis, caused by infection with Mycobacterium bovis, is a major endemic disease affecting cattle populations worldwide, despite the implementation of stringent surveillance and control programs in many countries. The development of high-throughput functional genomics technologies, including gene expression microarrays and RNA-sequencing (RNA-seq), has enabled detailed analysis of the host transcriptome to M. bovis infection, particularly at the macrophage and peripheral blood level. In the present study, we have analyzed the peripheral blood leukocyte (PBL) transcriptome of eight natural M. bovis-infected and eight age- and sex-matched non-infected control Holstein-Friesian animals using RNA-seq. In addition, we compared gene expression profiles generated using RNA-seq with those previously generated using the high-density Affymetrix(®) GeneChip(®) Bovine Genome Array platform from the same PBL-extracted RNA. A total of 3,250 differentially expressed (DE) annotated genes were detected in the M. bovis-infected samples relative to the controls (adjusted P-value ≤0.05), with the number of genes displaying decreased relative expression (1,671) exceeding those with increased relative expression (1,579). Ingenuity(®) Systems Pathway Analysis (IPA) of all DE genes revealed enrichment for genes with immune function. Notably, transcriptional suppression was observed among several of the top-ranking canonical pathways including Leukocyte Extravasation Signaling. Comparative platform analysis demonstrated that RNA-seq detected a larger number of annotated DE genes (3,250) relative to the microarray (1,398), of which 917 genes were common to both technologies and displayed the same direction of expression. Finally, we show that RNA-seq had an increased dynamic range compared to the microarray for estimating differential gene expression
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