Chaos-induced transparency in an ultrahigh-Q optical microcavity

We demonstrate experimentally a new form of induced transparency, i.e., chaos-induced transparency, in a slightly deformed microcavity which support both continuous chaotic modes and discrete regular modes with Q factors exceeding 3X?10^7. When excited by a focused laser beam, the induced transparency in the transmission spectrum originates from the destructive interference of two parallel optical pathways: (i) directly refractive excitation of the chaotic modes, and (ii) excitation of the ultra-high-Q regular mode via chaos-assisted dynamical tunneling mechanism coupling back to the chaotic modes. By controlling the focal position of the laser beam, the induced transparency experiences a highly tunable Fano-like asymmetric lineshape. The experimental results are modeled by a quantum scattering theory and show excellent agreement. This chaos-induced transparency is accompanied by extremely steep normal dispersion, and may open up new possibilities a dramatic slow light behavior and a significant enhancement of nonlinear interactions.Comment: 5 pages, 5 figue

Variations of China's emission estimates:Response to uncertainties in energy statistics

The accuracy of China's energy statistics is of great concern because it contributes greatly to the uncertainties in estimates of global emissions. This study attempts to improve the understanding of uncertainties in China's energy statistics and evaluate their impacts on China's emissions during the period of 1990-2013. We employed the Multi-resolution Emission Inventory for China (MEIC) model to calculate China's emissions based on different official data sets of energy statistics using the same emission factors. We found that the apparent uncertainties (maximum discrepancy) in China's energy consumption increased from 2004 to 2012, reaching a maximum of 646Mtce (million tons of coal equivalent) in 2011 and that coal dominated these uncertainties. The discrepancies between the national and provincial energy statistics were reduced after the three economic censuses conducted during this period, and converging uncertainties were found in 2013. The emissions calculated from the provincial energy statistics are generally higher than those calculated from the national energy statistics, and the apparent uncertainty ratio (the ratio of the maximum discrepancy to the mean value) owing to energy uncertainties in 2012 took values of 30.0, 16.4, 7.7, 9.2 and 15.6%, for SO2, NOx, VOC, PM2.5 and CO2 emissions, respectively. SO2 emissions are most sensitive to energy uncertainties because of the high contributions from industrial coal combustion. The calculated emission trends are also greatly affected by energy uncertainties - from 1996 to 2012, CO2 and NOx emissions, respectively, increased by 191 and 197% according to the provincial energy statistics but by only 145 and 139% as determined from the original national energy statistics. The energy-induced emission uncertainties for some species such as SO2 and NOx are comparable to total uncertainties of emissions as estimated by previous studies, indicating variations in energy consumption could be an important source of China's emission uncertainties

AccidentGPT: Large Multi-Modal Foundation Model for Traffic Accident Analysis

Traffic accident analysis is pivotal for enhancing public safety and developing road regulations. Traditional approaches, although widely used, are often constrained by manual analysis processes, subjective decisions, uni-modal outputs, as well as privacy issues related to sensitive data. This paper introduces the idea of AccidentGPT, a foundation model of traffic accident analysis, which incorporates multi-modal input data to automatically reconstruct the accident process video with dynamics details, and furthermore provide multi-task analysis with multi-modal outputs. The design of the AccidentGPT is empowered with a multi-modality prompt with feedback for task-oriented adaptability, a hybrid training schema to leverage labelled and unlabelled data, and a edge-cloud split configuration for data privacy. To fully realize the functionalities of this model, we proposes several research opportunities. This paper serves as the stepping stone to fill the gaps in traditional approaches of traffic accident analysis and attract the research community attention for automatic, objective, and privacy-preserving traffic accident analysis.Comment: 8 pages, 2 figure

Activity Day for the Older People on Nutrition in Attendo Siltalanpuisto : Project thesis

Nutrition plays a central role in supporting the health, functional ability, and quality of life of aging individuals. A balanced diet equips the body with the ability to manage various illnesses, such as cancer, diabetes, Parkinson's disease, autoimmune conditions, stroke, heart disease, and many other non-communicable diseases. Proper nutrition aids the recovery process, improves mood, and reduces healthcare costs. It also supports the aging process by facilitating the management of functional abilities. However, nutrition alone will not yield significant benefits; without exercise, the positive effects of eating well are limited. Therefore, combining proper nutrition with physical activity allows older individuals to achieve maximum benefits. The purpose of this project thesis was to design and implement a nutritionfocused activity day for older adults at Attendo Siltalanpuisto. The objective was to raise awareness among older individuals about the importance of nutrition and exercise in maintaining overall health. The project encompasses the planning phase, activity day implementation, theoretical background, and methodology. Information for the project was gathered from various sources, including PubMed, CINAHL, EBSCO, and Google Scholar, all of which provided relevant data on nutrition and exercise for older adults. The materials developed included a guidance folder on nutrition with pictures and illustrations, as well as exercise demonstration materials featuring visual aids. A questionnaire was also included to gather feedback and facilitate evaluation. The outcome of this project provided updated insights into nutrition and exercise for older adults, benefiting both the participants and the project team. For the team, it offered valuable experience in project implementation through teaching and demonstrations. Interaction with the facility allowed the group to better understand the practical aspects of the situation, as opposed to theoretical teaching in a classroom setting. The waterfall project management methodology was applied in this thesis. The success of the project was made possible by adopting a step-by-step approach, which enabled continuous assessment and evaluation at each phase

Unlocking the mystery of the hard-to-sequence phage genome: PaP1 methylome and bacterial immunity

BACKGROUND: Whole-genome sequencing is an important method to understand the genetic information, gene function, biological characteristics and survival mechanisms of organisms. Sequencing large genomes is very simple at present. However, we encountered a hard-to-sequence genome of Pseudomonas aeruginosa phage PaP1. Shotgun sequencing method failed to complete the sequence of this genome. RESULTS: After persevering for 10 years and going over three generations of sequencing techniques, we successfully completed the sequence of the PaP1 genome with a length of 91,715 bp. Single-molecule real-time sequencing results revealed that this genome contains 51 N-6-methyladenines and 152 N-4-methylcytosines. Three significant modified sequence motifs were predicted, but not all of the sites found in the genome were methylated in these motifs. Further investigations revealed a novel immune mechanism of bacteria, in which host bacteria can recognise and repel modified bases containing inserts in a large scale. This mechanism could be accounted for the failure of the shotgun method in PaP1 genome sequencing. This problem was resolved using the nfi(-) mutant of Escherichia coli DH5α as a host bacterium to construct a shotgun library. CONCLUSIONS: This work provided insights into the hard-to-sequence phage PaP1 genome and discovered a new mechanism of bacterial immunity. The methylome of phage PaP1 is responsible for the failure of shotgun sequencing and for bacterial immunity mediated by enzyme Endo V activity; this methylome also provides a valuable resource for future studies on PaP1 genome replication and modification, as well as on gene regulation and host interaction. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1471-2164-15-803) contains supplementary material, which is available to authorized users

Strategies for controlling pollution from vehicular emissions in Beijing

This paper describes the severe situation of vehicular emission pollution in Beijing, and discusses the following mitigation strategies: improving fuel quality, controlling the exhaust from new vehicles, controlling the emissions from vehicles in use through, e.g., Inspection/Maintenance (I/M), renovating in-use vehicles and scrapping of old vehicles, and road infrastructure and traffic policies

Contagious bank runs and committed liquidity support

In a crisis, regulators and private investors can find it difficult, if not impossible, to tell whether banks facing runs are insolvent or merely illiquid. We introduce such an information constraint into a global-games-based bank run model with multiple banks and aggregate uncertainties. The information constraint creates a vicious cycle between contagious bank runs and falling asset prices and limits the effectiveness of traditional emergency liquidity assistance programs. We explain how a regulator can set up committed liquidity support to contain contagion and stabilize asset prices even without information on banks’ solvency, rationalizing some recent developments in policy practices

A STUDY ON ISOLATION OF CHEMICAL CONSTITUENTS FROM SOPHORA FLAVESCENS AIT. AND THEIR ANTI-GLIOMA EFFECTS

Background: Sophora flavescens Ait. is a traditional Chinese medicine with a long history in China. It is mainly used in the treatment of heat dysentery and similar ailments in the clinical. The objective of this paper was to isolate, purify and identify alkaloids from Sophora flavescens Ait. and to explore their inhibitory effects on C6 glioma cells. Materials and Methods: Column chromatography, extraction and NMR spectroscopy were used to structurally identify the isolated compounds. MTT assay and flow cytometry were used to detect the inhibitory effect of matrine on C6 cells. Results: Three compounds were isolated from Sophora flavescens Ait., namely matrine, oxymatrine and lupeol. Different concentrations of matrine solution all had inhibitory effects on growth of C6 cell lines, which showed apparent dose-effect relationship. Compared with the control group, proportion of G0/G1 phase cells increased in each matrine concentration group to a maximum of 79.8%; proportion of S phase cells reduced, and proportion of G2/M phase cells declined slightly to a minimum of 6.3%, suggesting that after the action of matrine proliferation of C6 cells was significantly inhibited and the cells were arrested in the G1 phase. Conclusion: We concluded that Sophora flavescens Ait. has an inhibitory effect on C6 cell proliferation

Immune-related genes of the larval Holotrichia parallela in response to entomopathogenic nematodes Heterorhabditis beicherriana LF

Background: Entomopathogenic nematodes (EPNs) emerge as compatible alternatives to conventional insecticides in controlling Holotrichia parallela larvae (Coleoptera: Scarabaeidae). However, the immune responses of H. parallela against EPNs infection remain unclear. Results: In present research, RNA-Seq was firstly performed. A total of 89,427 and 85,741 unigenes were achieved from the midgut of H. parallela larvae treated with Heterorhabditis beicherriana LF for 24 and 72 h, respectively; 2545 and 3156 unigenes were differentially regulated, respectively. Among those differentially expressed genes (DEGs), 74 were identified potentially related to the immune response. Notably, some immune-related genes, such as peptidoglycan recognition protein SC1 (PGRP-SC1), pro-phenoloxidase activating enzyme-I (PPAE-I) and glutathione s-transferase (GST), were induced at both treatment points. Bioinformatics analysis showed that PGRP-SC1, PPAE-I and GST were all involved in anti-parasitic immune process. Quantitative real-time PCR (qRT-PCR) results showed that the three immune-related genes were expressed in all developmental stages; PGRP-SC1 and PPAE-I had higher expressions in midgut and fat body, respectively, while GST exhibited high expression in both of them. Moreover, in vivo silencing of them resulted in increased susceptibility of H. parallela larvae to H. beicherriana LF. Conclusion: These results suggest that H. parallela PGRP-SC1, PPAE-I and GST are involved in the immune responses to resist H. beicherriana LF infection. This study provides the first comprehensive transcriptome resource of H. parallela exposure to nematode challenge that will help to support further comparative studies on host-EPN interactions