The normative implications of the longevity transition

This paper explores some of the normative implications of changes in the age profile of longevity improvements. The discussion assumes that in many ageing societies there is still a sense of collective ambivalence about the benefits conferred by continuing longevity increases. Different approaches are considered to making a collective reckoning of the benefits conferred by continuing longevity gains when the age profile of these gains is undergoing profound change. The requirement to make such reckonings raises novel normative problems for policy

First Record of a Bloom of Gonyaulax monilata in Coastal Waters of Mississippi

Data are presented on a bloom of the toxic dinoflagellate Gonyaulax monilata in coastal waters of Florida, Alabama, Mississippi and Louisiana. This paper documents the first record of a bloom of this species in Mississippi Sound and adjacent Gulf of Mexico

Psychosocial aspects of successful ageing and resilience: critique, integration and implications

As the number of older adults increases worldwide, it is becoming increasingly important to find effective ways of fostering better aging trajectories. The models used to shape this process inform research, policy, practice and impact older adults themselves. Two important aging models are successful aging(SA) and resilience(RES). Aligning the conceptual framework in research contexts with those of older adults’ perspectives is an integral component of driving forward the research agenda in a manner that has the greatest potential benefit older adults. Studies conducted with laypersons indicate that psychosocial components are important components of successful aging models; therefore, it is imperative that these non-biomedical components are incorporated. There are many similarities between SA and RES models, but an important distinguishing feature is the incorporation of adversity into conceptualizations of resilience. SA models suggest high levels of functioning as a requirement for aging successfully, regardless of the circumstances the individual experiences; resilience models take into account the level of adversity being experienced by the individual. Individuals can demonstrate RES by having a more positive outcome than would be expected given their level of adversity. The incorporation of psychosocial constructs into SA models and the integration of SA and RES paradigms has important implications for research and for older adults themselves. Through the promotion of models of aging that include psychosocial components and elements of adversity, greater generalizability to a broader population is possible with enhanced potential for research derived from these efforts to more positively influence individuals’ trajectories of aging

First Record of a Bloom of Gonyaulax monilata in Coastal Waters of Mississippi

Data are presented on a bloom of the toxic dinoflagellate Gonyaulax monilata in coastal waters of Florida, Alabama, Mississippi and Louisiana. This paper documents the first record of a bloom of this species in Mississippi Sound and adjacent Gulf of Mexico

Statin prescribing according to gender, age and indication: what about the benefit-risk balance?

Rationales, aims and objectives The increasing dispensing of statins has raised concern about the appropriateness of prescribing to various population groups. We aimed to (1) investigate incident and prevalent statin prescribing according to indication, gender and age and (2) relate prescribing patterns to evidence on beneficial and adverse effects. Methods A cohort of Danish inhabitants (n = 4 424 818) was followed in nationwide registries for dispensed statin prescriptions and hospital discharge information. We calculated incidence rates (2005–2009), prevalence trends (2000–2010) and absolute numbers of statin users according to register proxies for indication, gender and age. Results In 2010, the prevalence became highest for ages 75–84 and was higher in men than women (37% and 33%, respectively). Indication‐specific incidences and prevalences peaked at ages around 65–70, but in myocardial infarction, the prevalence was about 80% at ages 45–80. Particularly, incidences tended to be lower in women until ages of about 60 where after gender differences were negligible. In asymptomatic individuals (hypercholesterolaemia, presumably only indication) aged 50+, dispensing was highest in women. The fraction of statin dispensing for primary prevention decreased with age: higher for incident than prevalent prescribing. Independent of age, this fraction was highest among women, e.g. 60% versus 45% at ages 55–64. The fraction for potential atherosclerotic condition (PAC, e.g. heart failure) increased with age. Conclusion Prevalence of statin utilization was highest for ages 75–84, although indication‐specific measures were relatively low. Despite inconclusive evidence for a favourable risk–benefit balance, statin prescribing was high among people aged 80+, asymptomatic women and PAC patients

Polyarchies, Competitive Oligarchies, or Inclusive Hegemonies? 23 Global Intergovernmental Organizations Compared

In this paper, I assume that global intergovernmental organizations (GIGOs) function as "enablers" of interstate liberal politics by way of their multilateral institutional frameworks. To support this view, I recall and adapt the classical concept of "polyarchy," coined in the early 1950s by Robert A. Dahl. It consists of a two-dimensional theoretical construct applicable for measuring the level of liberalization in modern political societies. It follows that the more actors who take part in politics, and the more that institutions allow political opposition, the more open a society (of states) is likely to be. I thus wish to assess and rate the level of "polyarchization" of 23 GIGOs that cover various issue areas and fit some specific criteria (for example, more than one hundred member states from at least three different continents). The methodology section includes a scorecard that I have specially developed to help achieve these research objectives

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries