146 research outputs found

    TINGKAT KERAWANAN DAN KEBUTUHAN PROTEKSI KEBAKARAN PADA KAWASAN PERMUKIMAN KUMUH DI JALAN KARYA MAKMUR DENPASAR

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    The residential area on Jalan Karya Makmur is one of the slum areas in Denpasar City. This settlement is a priority for fire management because it has a very high fire vulnerability. The level of vulnerability and handling of fire protection in slums that will be applied is the analysis of fire risk level assessment, seeing the prioritization of fire protection needs criteria, and handling carried out in the study area. This research aims to find out how the handling of fire protection in slum areas is suitable to be applied to the study area. with quantitative descriptive research methods, namely data that describes the conditions of the research location with tabulated numbers and descriptions that can be calculated to determine the desired value. The type of data in question is the analysis in this study, namely 9 fire protection criteria and data related to the research.Kawasan Permukiman di Jalan Karya Makmur adalah salah satu kawasan permukiman kumuh yang ada di Kota Denpasar. Permukiman ini menjadi prioritas penanganan kebakaran karena memiliki kerawanan kebakaran yang sangat tinggi. Tingkat kerawanan dan penanganan proteksi kebakaran pada Permukiman Kumuh yang akan diterapkan adalah Analisa Penilaian tingkat resiko kebakaran, melihat prioritas kriteria kebutuhan proteksi kebakaran, serta Penanganan yang dilakukan dalam kawasan studi. Penelitian ini bertujuan mengetahui bagaimana penanganan dalam proteksi kebakaran pada kawasan permukiman kumuh yang cocok untuk diterapkan pada kawasan studi. dengan metode penelitian Deskriptif kuantitatif, yaitu data yang menjelaskan kondisi- kondisi lokasi penelitian dengan tabulasi angka-angka serta penggambaran yang dapat dikalkulasikan untuk mengetahui nilai yang diinginkan. Adapun jenis data yang dimaksud adalah analisis Dalam penelitian ini yaitu 9 kriteria proteksi kebakaran serta data- data yang berhubungan dengan penelitian

    The Law Enforcement Against The Crime Of Illegal Mining

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    This study aims to determine law enforcement against the criminal act of illegal mining in the jurisdiction of the Central Kalimantan Regional Police and the obstacles that arise in law enforcement of the criminal act of illegal mining in the jurisdiction of the Central Kalimantan Regional Police and their solutions. The approach method used is sociological juridical, descriptive analytical research specifications, types and sources of data using primary and secondary data, data collection methods are field studies and literature studies, while the data analysis method uses qualitative analysis. The results of the study indicate that law enforcement for the criminal act of illegal mining in the jurisdiction of the Central Kalimantan Regional Police is carried out through preventive and repressive efforts. Repressive efforts are carried out with outreach activities to the community at the Polres and Polsek levels, while repressive efforts through a series of investigative actions. There are several obstacles in the law enforcement process, namely the presence of irresponsible individuals, limited facilities and infrastructure and a lack of legal awareness from the community

    Impak polisi kolonial dan krisis global terhadap sekuriti makanan di Nigeria (1900 1920)

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    Artikel ini mengkaji kesan dasar kolonial British dan krisis global seperti Perang Dunia I dan pandemik Selesema Sepanyol terhadap sekuriti makanan di Nigeria dari tahun 1900 hingga 1920. Melalui pendekatan penyelidikan pelbagai kaedah yang merangkumi analisis dokumen sejarah dan analisis perbandingan dengan wilayah lain, kajian ini mendedahkan dinamik kompleks yang membentuk landskap pertanian dan sekuriti makanan Nigeria dalam tempoh kritikal ini. Penyelidikan itu menyerlahkan bagaimana strategi ekonomi kolonial yang bertujuan untuk mengintegrasikan Nigeria ke dalam pasaran global melalui penanaman tanaman tunai secara signifikan mengganggu sistem pengeluaran makanan tempatan. Pada masa yang sama, permintaan Perang Dunia I untuk sumber dan tenaga kerja mengalihkan perhatian dan sumber daripada pertanian sara diri, dan telah memburukkan lagi isu kekurangan makanan. Keadaan bertambah buruk dengan pandemik Selesema Sepanyol pada 1918-1919, yang memusnahkan penduduk, termasuk buruh pertanian yang penting, seterusnya menjejaskan sekuriti makanan. Kajian ini menyumbang kepada pemahaman sejarah sekuriti makanan di Nigeria dengan menyediakan analisis bernuansa tentang cara penjajahan, konflik global dan penyakit pandemik secara kolektif mempengaruhi amalan pertanian, ketersediaan makanan dan keputusan dasar. Penemuan ini menekankan kepentingan untuk mempertimbangkan konteks sejarah dalam merangka strategi sekuriti makanan kontemporari dan penggubalan dasar, terutamanya di wilayah yang mempunyai legasi penjajah yang serupa. Dengan mengambil pengajaran daripada masa lalu, artikel ini menawarkan pandangan untuk menangani cabaran sekuriti makanan pada masa kini dan akan datang, menekankan keperluan untuk amalan pertanian yang berdaya tahan dan mampan yang boleh menahan kejutan luaran

    Combined intraarterial/intravenous thrombolysis for acute ischemic stroke

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    BACKGROUND AND PURPOSE: The intravenous use of recombinant tissue-type plasminogen activator (rTPA) in acute ischemic stroke has been investigated in three large trials. Limited series have reflected outcome after local intraarterial thrombolysis (LIT) in the cerebral territory. The purpose of this study was to evaluate the safety and efficacy of combined intraarterial/intravenous thrombolysis using rTPA (actilyse) for acute ischemic stroke. METHODS: Forty-five patients with acute onset of severe hemispheric stroke and without signs of major cerebral infarction on early CT scans were randomized by order of admission. Twelve patients were treated with 50 mg actilyse (maximal dose, 0.7 mg/kg); three had occlusion of the internal carotid artery and nine had occlusion of the middle cerebral artery. Thrombolysis was started by LIT and continued intravenously within 6 hours of stroke onset. Outcome, assessed after 1 and 12 months according to the modified Rankin scale (MRS), was considered good (MRS score, 0-3) for patients who were functionally independent and poor (MRS score, 4-5) for those who were dependent or had died. RESULTS: In the thrombolysis group, outcome was good in eight patients at 1 month and in 10 patients at 12 months; in the control group, outcome was good in seven (21%) and 11 (33%) patients, respectively. Of the eight patients with a good outcome after thrombolysis, four had complete and one had partial recanalization. In the control group, the rate of intracerebral hemorrhage was 6%. Mortality at 1 month in the thrombolysis and control groups was 17% and 48%, respectively. CONCLUSIONS: Combined intraarterial/intravenous thrombolysis with low-dose rTPA may be a safe and effective treatment for acute ischemic stroke within 6 hours in carefully selected patients.Peer reviewe

    Preliminary results of randomized controlled study on decompressive craniectomy in treatment of malignant middle cerebral artery stroke

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    Background and Objective. Studies on decompressive craniectomy (DCE) after a malignant middle cerebral artery (MCA) stroke in selected population show an increased probability of survival without increasing the number of very severely disabled. Cerebral infarct volume (CIV) as a triage criterion for performing surgery has not been discussed in literature. The aim of this study was to investigate the value of CIV and initial National Institutes of Health Stroke Scale (NIHHS) and Glasgow Coma Scale (GCS) scores as possible triage criteria in the surgical treatment of patients with " malignant" MCA stroke. Material and Methods. According to the study protocol, 28 patients with a malignant MCA stroke were included and analyzed prospectively. The patients were randomly divided either into the DCE plus best medical treatment (BMT) group or BMT alone group. CIV and NIHHSand GCS scores were measured at time of enrollment in every case. Clinical outcome was evaluated 1 year after the treatment. Results. Six patients survived: 5 in the DCE group (none of them was older than 60 years) and 1 in the BMT group (P=0.03/0.06).Among survivors, none had a cerebral infarct volume of more than 390 cm3 (P=0.05). Allsurvivors inthe DCE group had favorable outcomes. There was no significant difference inthe NIHSS and GCS scores between the groups and survivors/nonsurvivors (P>0.05). Conclusions. Decompressive surgery in the selected patients is likely to increase the probability of survival with a favorable outcome without increasing the number of severely disabled survivors. Patients with CIV of more than 390 cm3 may be bad candidates for DCE, and the prognosis is likely to be bad regardless the treatment strategy. The initial NIHHS and GCS scores did not prove any prognostic value in outcome.publishersversionPeer reviewe

    Long-term effects of the interruption of the Dutch breast cancer screening program due to COVID-19:A modelling study

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    Due to COVID-19, the Dutch breast cancer screening program was interrupted for three months with uncertain long-term effects. The aim of this study was to estimate the long-term impact of this interruption on delay in detection, tumour size of screen-detected breast cancers, and interval cancer rate. After validation, the micro-simulation model SiMRiSc was used to calculate the effects of interruption of the breast cancer screening program for three months and for hypothetical interruptions of six and twelve months. A scenario without interruption was used as reference. Outcomes considered were tumour size of screen-detected breast cancers and interval cancer rate. Women of 55–59 and 60–64 years old at time of interruption were considered. Uncertainties were estimated using a sensitivity analysis. The three-month interruption had no clinically relevant long-term effect on the tumour size of screen-detected breast cancers. A 19% increase in interval cancer rate was found between last screening before and first screening after interruption compared to no interruption. Hypothetical interruptions of six and twelve months resulted in larger increases in interval cancer rate of 38% and 78% between last screening before and first screening after interruption, respectively, and an increase in middle-sized tumours in first screening after interruption of 26% and 47%, respectively. In conclusion, the interruption of the Dutch screening program is not expected to result in a long-term delay in detection or clinically relevant change in tumour size of screen-detected cancers, but only affects the interval cancer rate between last screening before and first screening after interruption

    A Better Response: Improving Americaâs Mental Health Crisis System

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    Every day, people experience mental health, substance use, and suicidal emergencies. In a survey published in October 2022, half (51%) of all adults nationwide said someone in their family had experienced a severe mental health crisis.Too often, those in crisis don't know who to turn to, and many don't receive the care they need. Every minute, an average of two people will attempt suicide; three people with a mental health condition will be booked into a jail; and eight calls, texts, and chats will be made to the 988 Suicide & Crisis Lifeline (988 call centers).While states across the country have made significant strides in improving crisis services in recent years, more is needed to ensure no one's worst day keeps them from living their best life. To that end, this report features policy solutions designed to advance the following three goals:Everyone in a mental health crisis receives the right services at the right time and has a supportive, recovery-oriented experience of care.Youth in mental health crisis and their families receive developmentally-appropriate services and supports.Law enforcement involvement in a mental health crisis is the exception, not the rule

    HPV types and variants among cervical cancer tumors in three regions of Tunisia

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    Cervical cancer is the second most common cancer among Tunisian women, and the incidence rates vary by region. Three Tunisian registries report age-standardized rates of 6.3/10 5 in the central region, 5.4/10 5 in the north, and 2.7/10 5 in the south. High-risk human papillomavirus (HPV) types and their variants differ in carcinogenic potential and geographic distribution. The HPV type and variant distribution could be a factor in the differing rates between regions of Tunisia. Tumor tissue was collected from 142 Tunisian cervical cancer patients. Demographic and reproductive characteristics of the patients were abstracted from cancer registry and hospital records. HPV type and variant analyses were performed using PCR-based Luminex and dot-blot hybridization assays. Eighty-three percent of tumors were infected with at least one HPV type. European variants of HPV16/18 were the most prevalent in tumors from all three regions, with all HPV18 infections and 64% of HPV16 infections being of European lineage. A higher frequency of HPV16 was present in Northern Tunisia (80%) than in Central (68%) or Southern Tunisia (50%) ( P  = 0.02). HPV18/45 was significantly more common in adenocarcinomas (50%) than in squamous cell carcinomas (11%) ( P  = 0.004). Frequent infection with European HPV variants most likely reflects the history of European migration to Tunisia. In addition to the importance of understanding the variants of HPV in Tunisia, behavioral and cultural attitudes towards screening and age-specific infection rates should be investigated to aid the development of future vaccination and HPV screening programs and policies. J. Med. Virol. 83:651–657, 2011. © 2011 Wiley-Liss, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/83181/1/22011_ftp.pd

    Overdiagnosis of invasive breast cancer in population-based breast cancer screening:A short- and long-term perspective

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    BACKGROUND: Overdiagnosis of invasive breast cancer (BC) is a contentious issue. OBJECTIVE: The aim of this paper is to estimate the overdiagnosis rate of invasive BC in an organised BC screening program and to evaluate the impact of age and follow-up time. METHODS: The micro-simulation model SiMRiSc was calibrated and validated for BC screening in Flanders, where women are screened biennially from age 50 to 69. Overdiagnosis rate was defined as the number of invasive BC that would not have been diagnosed in the absence of screening per 100,000 screened women during the screening period plus follow-up time (which was set at 5 years and varied from 2 to 15 years). Overdiagnosis rate was calculated overall and stratified by age. RESULTS: The overall overdiagnosis rate for women screened biennially from 50 to 69 was 20.1 (95%CI: 16.9-23.2) per 100,000 women screened at 5-year follow-up from stopping screening. Overdiagnosis at 5-year follow-up time was 12.9 (95%CI: 4.6-21.1) and 74.2 (95%CI: 50.9-97.5) per 100,000 women screened for women who started screening at age 50 and 68, respectively. At 2- and 15-year follow-up time, overdiagnosis rate was 98.5 (95%CI: 75.8-121.3) and 13.4 (95%CI: 4.9-21.9), respectively, for women starting at age 50, and 297.0 (95%CI: 264.5-329.4) and 34.2 (95%CI: 17.5-50.8), respectively, for those starting at age 68. CONCLUSIONS: Sufficient follow-up time (≥10 years) after screening stops is key to obtaining unbiased estimates of overdiagnosis. Overdiagnosis of invasive BC is a larger problem in older compared to younger women
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