"Creating cultural safety with Indigenous clients as a settler drama therapist": A heuristic study.

This research paper accompanies a ten page zine that supports non-Indigenous drama therapists in striving towards achieving cultural safety within their relationships with Indigenous clients. The zine and accompanying research paper document my personal process of cultural learning about Indigenous clients and communities, and my understanding of their potential needs vis-a-vis non-Indigenous care workers. In these documents, I share what I have learned about establishing cultural safety from an Indigenous perspective, and the specific cultural needs of Indigenous clients, whilst connecting my new knowledge within the framework of Western therapeutic ethics. This paper consists of a literature review that discusses Western models of cultural care and Indigenous perspectives on health and cultural safety, surveying the positive and negative efforts that Western systems of counselling and therapy have attempted within Indigenous communities, and highlighting specific ways to reconcile these relationships between Indigenous clients and non-Indigenous therapists. In this paper, I review past research, present the steps of my heuristic process from data collection to analysis and, finally, synthesize my results creatively into a zine

Investigation of the buckling behavior of pinned pinned hat-shaped members using newly introduced software OpenFSM

Cold formed sections design has always been a subject of engineer’s interest. Along the years, engineers and designers studied these sections due to their high structural efficiency (High strength to weight ratio) and thus their high economic privilege over hot rolled and the built-up sections. The Direct Strength method is a recently adopted design approach where it requires no effective section calculations and requires no iterations instead it depends on analyzing the member using numerical analysis method (Finite Strip Method, Generalized Beam Theory or Finite element method) utilizing the section gross properties to obtain the critical elastic buckling loads for different buckling modes including (Local Buckling, Distortional Buckling and Global Buckling modes). Computational tools using finite strip method like CUFSM, GBTUL and THIN-WALL are to be used for that purpose. The study introduces newly finite strip analysis program (OpenFSM) offering alternative analysis tool with easier interface including features that can facilitate the design process and offer more potential for conducting parametric studies and research projects. The software is verified with similar case studies investigated in the widely used program CUFSM. The proposed software is then utilized in performing parametric studies on pinned-pinned hat-shaped members under different loading conditions. Equations and charts are presented to calculate the critical local buckling stress of hat-shaped members subjected to the different investigated loading conditions. Moreover, several interesting observations, conclusions, and recommendations are deducted.The authors would like to thank the contribution of the team of AGECS Research Center (ARC) for their help to get this research and developed software to a professional level

AN APPROACH FOR SUSTAINABLE AFFORDABLE HOUSESDESIGN IN EGYPT

Achieving sustainability is an important factor to be considered in the architectural design process, there is an important need to consider sustainability in affordable houses design. The research problem is the presence of many affordable houses in Egypt without considering the terms of sustainability, and also the increasing the numbers of these projects in Egypt. By studying the current situation of most affordable houses projects in Egypt, a lack of achieving sustainability requirements appear , which led to the need for an approach to meet these requirements in affordable houses design. The research includes a theoretical study of the sustainability requirements when designing new affordable houses, with concerning about achieving the design requirements for users, considering the project cost and applying the requirements of sustainability to be matching with the local environment. The search includes an analytical study of some international case studies that include some of sustainability applications, determining the advantages and the latest international ideas in the field of sustainable affordable houses. The analytical study includes also a local affordable houses project in Cairo in Egypt identifying the most important shortcomings in sustainability achievement in this project. The research aims to propose an approach to achieve sustainability in the affordable houses design and to be applicable to apply to the projects in Cairo, Egypt, where the research concluded a design approach to achieve sustainability of affordable houses projects in Cairo in Egypt considering of the local factors, matching with local environment and international developments

Quantification of three macrolide antibiotics in pharmaceutical lots by HPLC: Development, validation and application to a simultaneous separation

A new validated high performance liquid chromatographic (HPLC) method with rapid analysis time and high efficiency, for the analysis of erythromycin, azithromycin and spiramycin, under isocratic conditions with ODB RP18 as a stationary phase is described. Using an eluent composed of acetonitrile –2-methyl-2-propanol –hydrogenphosphate buffer, pH 6.5, with 1.5% triethylamine (33:7: up to 100, v/v/v), delivered at a flow-rate of 1.0 mL min-1. Ultra Violet (UV) detection is performed at 210 nm. The selectivity is satisfactory enough and no problematic interfering peaks are observed. The procedure is quantitatively characterized and repeatability, linearity, detection and quantification limits are very satisfactory. The method is applied successfully for the assay of the studied drugs in pharmaceutical dosage forms as tablets and powder for oral suspension. Recovery experiments revealed recovery of 97.13–100.28%

Child health and survival in the eastern mediterranean region

Most child deaths in the region are preventable and occur in just a few of the 22 countries in the region. The interventions are not expensive, but governments need to implement the

Contribution of coagulation factor VII R353Q polymorphism to the risk of thrombotic disorders development (venous and arterial): A case-control study

Background: Elevated factor VII (FVII) level is a risk factor for thromboembolic disorders. It was reported that the FVII R353Q polymorphism is associated with variation in plasma FVII levels, where Q allele carriers were more associated with lower levels of FVII than R allele carriers. However, the association between coagulation FVII R353 Q polymorphisms and the risk of thrombosis is uncertain.Aim of the study: Is to investigate the contribution of factor VII R353Q gene polymorphism to the risk of thrombotic disorders development (venous and arterial) in a group of Egyptian patients.Subjects and methods: This study was conducted on 310 subjects: 110 acute myocardial infarction (AMI) patients, 108 deep venous thrombosis (DVT) patients and 92 healthy controls. FVII R353Q genotypes were assessed using restriction fragment length polymorphism analysis.Results: There were no statistically significant differences in the frequency of FVII R353Q polymorphism between each of the AMI and DVT patients and the control group (P = 0.9, 0.1). However the Q allele showed a significantly higher frequency in the AMI group (15.4%) vs. controls (8.7%) (OR: 1.92; 95% CI: 0.98–3.7). Bivariate analysis demonstrated no significant association between FVII R353Q genotypes and different studied risk factors, neither in arterial nor venous thrombosis.Conclusion: FVII R353Q polymorphism did not contribute to an increased risk of thrombosis (arterial and venous); also carrying the Q allele (of R353Q) did not confer protection against acute thrombotic events

Polymeric-Calcium Phosphate Cement Composites-Material Properties: In Vitro and In Vivo Investigations

New polymeric calcium phosphate cement composites (CPCs) were developed. Cement powder consisting of 60 wt% tetracalcium phosphate, 30 wt% dicalcium phosphate dihydrate, and 10 wt% tricalcium phosphate was combined with either 35% w/w poly methyl vinyl ether maleic acid or polyacrylic acid to obtain CPC-1 and CPC-2. The setting time and compressive and diametral tensile strength of the CPCs were evaluated and compared with that of a commercial hydroxyapatite cement. In vitro cytotoxicity and in vivo biocompatibility of the two CPCs and hydroxyapatite cement were assessed. The setting time of the cements was 5–15 min. CPC-1 and CPC-2 showed significantly higher compressive and diametral strength values compared to hydroxyapatite cement. CPC-1 and CPC-2 were equivalent to Teflon controls after 1 week. CPC-1, CPC-2, and hydroxyapatite cement elicited a moderate to intense inflammatory reaction at 7 days which decreased over time. CPC-1 and CPC-2 show promise for orthopedic applications

Remote sensing techniques and geochemical constraints on the formation of the Wadi El-Hima mineralized granites, Egypt: new insights into the genesis and accumulation of garnets

The Wadi El-Hima Neoproterozoic I- and A-type granites in the Southern Eastern Desert of Egypt are rich in garnets (up to 30 vol%) and are cut by NW–SE strike-slip faults, as confirmed from structure lineament extraction maps. These mineralized granites and garnet mineralization zones can be successfully discriminated using remote sensing techniques. Spectral angle mapper and matched filtering techniques are highly effective for mapping garnet-rich zones and show that the highest garnet concentrations occur along the intrusive contact zone of NW–SE striking faults. El-Hima granites have high SiO2 (73.5–75.1 wt%), Al2O3 (13.4–15.3 wt%) and total alkali (6.7–8.7 wt%) contents, suggesting that they were sourced from peraluminous (A/CNK > 1) parental magmas. Garnet-bearing trondhjemites are metasomatic in origin and formed after I-type tonalite-granodiorites, which originated in a volcanic arc tectonic setting. Garnet-rich syenogranites and alkali-feldspar granites are both post-collisional A-type granites: the syenogranites formed from peraluminous magmas generated by partial melting of lower crustal tonalite and metasedimentary protoliths during lithospheric delamination, and the alkali-feldspar granites crystallized from highly fractionated, felsic and alkali-rich peraluminous magmas in the upper crust. Garnets in El-Hima mineralized granites occur in three forms: (1) subhedral disseminated crystals, (2) vein-type crystals, and (3) aggregated subhedral crystals, reflecting different mechanisms of accumulation. All are dominantly almandine in composition (Alm76Sps10 Prp7Grs6Adr1) and have high average concentrations of heavy rare earth elements (HREE) (ΣHREE = 1636 ppm), Y = (3394 ppm), Zn (325 ppm), Li (39.17 ppm) and Ga (34.94 ppm). Garnet REE patterns show strong negative Eu anomalies with HREE enriched relative to LREE, indicating a magmatic origin. These magmatic garnets are late-stage crystallization products of Al-rich hydrous magmas, and formed at low temperature (680–730 °C) and pressure (2.1–2.93 kbar) conditions in the upper continental crust. Peculiar garnet concentrations in syenogranites near and along contact zones with alkali feldspar granites are related to peraluminous parent hydrous magma compositions. These garnets formed by in situ crystallization from A-type granite melts, alongside accumulation of residual garnets left behind after partial melting of the host garnet-rich granites along the intrusive contact. Magmatic-fluid flow along the NW–SE striking fault of Najd system enhanced garnet accumulation in melts, which formed clots and veins of garnet

Preparation, Physical-Chemical Characterization, and Cytocompatibility of Polymeric Calcium Phosphate Cements

Aim. Physicochemical mechanical and in vitro biological properties of novel formulations of polymeric calcium phosphate cements (CPCs) were investigated. Methods. Monocalcium phosphate, calcium oxide, and synthetic hydroxyapatite were combined with either modified polyacrylic acid, light activated polyalkenoic acid, or polymethyl vinyl ether maleic acid to obtain Types I, II, and III CPCs. Setting time, compressive and diametral strength of CPCs was compared with zinc polycarboxylate cement (control). Specimens were characterized using X-ray diffraction, scanning electron microscopy, and infrared spectroscopy. In vitro cytotoxicity of CPCs and control was assessed. Results. X-ray diffraction analysis showed hydroxyapatite, monetite, and brushite. Acid-base reaction was confirmed by the appearance of stretching peaks in IR spectra of set cements. SEM revealed rod-like crystals and platy crystals. Setting time of cements was 5–12 min. Type III showed significantly higher strength values compared to control. Type III yielded high biocompatibility. Conclusions. Type III CPCs show promise for dental applications

Disturbed atrial metabolism, shear stress, and cardiac load contribute to atrial fibrillation after ablation:AXAFA biomolecule study

Aims: Different disease processes can combine to cause atrial fibrillation (AF). Their contribution to recurrent AF after ablation in patients is not known. Cardiovascular processes associated with recurrent AF after AF ablation were determined by quantifying biomolecules related to inflammation, metabolism, proliferation, fibrosis, shear stress, atrial pressure, and others in the AXAFA biomolecule study.Methods and results: Twelve circulating cardiovascular biomolecules (ANGPT2, BMP10, CA125, hsCRP, ESM1, FABP3, FGF23, GDF15, IGFBP7, IL6, NT-proBNP, and hsTnT) were quantified in plasma samples obtained prior to a first AF ablation using high-throughput, high-precision assays. Cox regression was used to identify biomolecules associated with recurrent AF during the first 3 months after AF ablation. In 433 patients (64 years [58, 70]; 33% women), baseline concentrations of ANGPT2, BMP10, hsCRP, FGF23, FABP3, GDF15, and NT-proBNP were elevated in patients with recurrent AF (120/433; 28%). After adjustment for 11 clinical features and randomized treatment, elevated NT-proBNP [hazard ratio (HR) 1.58, 95% confidence interval (1.29, 1.94)], ANGPT2 [HR 1.37, (1.12, 1.67)], and BMP10 [HR 1.24 (1.02, 1.51)] remained associated with recurrent AF. Concentrations of ANGPT2, BMP10, and NT-proBNP decreased in patients who remained arrhythmia free, but not in patients with recurrent AF, highlighting their connection to AF. The other eight biomarkers showed unchanged concentrations. Conclusion: Elevated concentrations of ANGPT2, BMP10, and NT-proBNP are associated with recurrent AF after a first AF ablation, suggesting that processes linked to disturbed cardiomyocyte metabolism, altered atrial shear stress, and increased load contribute to AF after AF ablation in patients