An investigation of the role of news values in the selection of news sources in a contemporary third world newspaper: a case study of the Daily Nation newspaper

News in our contemporary newspapers has come to be associated more and more with what the elites do and say. Both their deeds and misdeeds are treated as newsworthy events and in the process they become newsmakers, both actors and sources of news. Even when they are not directly involved in news events they are sought out by journalists to validate those events and to interpret the social reality to the readers as news sources. This study is about the selection of news sources in the Daily Nation, a contemporary, independent newspaper based in Nairobi, Kenya. In this study, I set out to unravel the complex processes that underlie newsmaking and source selection. This study is informed by the theory of news values and the paradigm of the role of media in democracy. Based on qualitative interviews, observations and content analysis of the front-page stories, it investigates the process of news and source selection in front-page stories. Through these approaches, I established that news values are significant criteria that inform journalists in both the selection of front-page news stories and the sources of these stories. I also established that social values of the society in which this newspaper operates are heavily embedded in the news. For example, the journalists preferred male politicians as sources of news in the front-page stories to women, and the elites to ordinary people, and this reflected on the social structures and cultural norms that are prevalent in this society. This study, further, established that the news values of this newspaper share commonly with the Western news media in terms of journalistic conventions and ways of interpreting the social reality in the news. Ideally, the newspaper embraces the principles of democracy in news reporting, but in practice it does not satisfactorily adhere to the full requirements of its democratic role in terms of source selection. The democratic principles in news reporting require, among other things, that the newspaper should allow a diversity of views in the news, representing various groups that are found in real society including the elites, non-elites, women, ordinary people and minorities. In the case of the Daily Nation, a tiny group of elite male professional politicians made up the largest majority of its front-page news sources

An investigation of the role of news values in the selection of news sources in a contemporary third world newspaper: a case study of the Daily Nation newspaper

News in our contemporary newspapers has come to be associated more and more with what the elites do and say. Both their deeds and misdeeds are treated as newsworthy events and in the process they become newsmakers, both actors and sources of news. Even when they are not directly involved in news events they are sought out by journalists to validate those events and to interpret the social reality to the readers as news sources. This study is about the selection of news sources in the Daily Nation, a contemporary, independent newspaper based in Nairobi, Kenya. In this study, I set out to unravel the complex processes that underlie newsmaking and source selection. This study is informed by the theory of news values and the paradigm of the role of media in democracy. Based on qualitative interviews, observations and content analysis of the front-page stories, it investigates the process of news and source selection in front-page stories. Through these approaches, I established that news values are significant criteria that inform journalists in both the selection of front-page news stories and the sources of these stories. I also established that social values of the society in which this newspaper operates are heavily embedded in the news. For example, the journalists preferred male politicians as sources of news in the front-page stories to women, and the elites to ordinary people, and this reflected on the social structures and cultural norms that are prevalent in this society. This study, further, established that the news values of this newspaper share commonly with the Western news media in terms of journalistic conventions and ways of interpreting the social reality in the news. Ideally, the newspaper embraces the principles of democracy in news reporting, but in practice it does not satisfactorily adhere to the full requirements of its democratic role in terms of source selection. The democratic principles in news reporting require, among other things, that the newspaper should allow a diversity of views in the news, representing various groups that are found in real society including the elites, non-elites, women, ordinary people and minorities. In the case of the Daily Nation, a tiny group of elite male professional politicians made up the largest majority of its front-page news sources

Meflin is a marker of pancreatic stellate cells involved in fibrosis and epithelial regeneration in the pancreas

Pancreatic stellate cells (PSCs) are stromal cells in the pancreas that play an important role in pancreatic pathology. In chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma (PDAC), PSCs are known to get activated to form myofibroblasts or cancer-associated fibroblasts (CAFs) that promote stromal fibroinflammatory reactions. However, previous studies on PSCs were mainly based on the findings obtained using ex vivo expanded PSCs, with few studies that addressed the significance of in situ tissue-resident PSCs using animal models. Their contributions to fibrotic reactions in CP and PDAC are also lesser-known. These limitations in our understanding of PSC biology have been attributed to the lack of specific molecular markers of PSCs. Herein, we established Meflin (Islr), a glycosylphosphatidylinositol-anchored membrane protein, as a PSC-specific marker in both mouse and human by using human pancreatic tissue samples and Meflin reporter mice. Meflin-positive (Meflin+) cells contain lipid droplets and express the conventional PSC marker Desmin in normal mouse pancreas, with some cells also positive for Gli1, the marker of pancreatic tissue-resident fibroblasts. Three-dimensional analysis of the cleared pancreas of Meflin reporter mice showed that Meflin+ PSCs have long and thin cytoplasmic protrusions, and are localised on the abluminal side of vessels in the normal pancreas. Lineage tracing experiments revealed that Meflin+ PSCs constitute one of the origins of fibroblasts and CAFs in CP and PDAC, respectively. In these diseases, Meflin+ PSC-derived fibroblasts showed a distinctive morphology and distribution from Meflin+ PSCs in the normal pancreas. Furthermore, we showed that the genetic depletion of Meflin+ PSCs accelerated fibrosis and attenuated epithelial regeneration and stromal R-spondin 3 expression, thereby implying that Meflin+ PSCs and their lineage cells may support tissue recovery and Wnt/R-spondin signalling after pancreatic injury and PDAC development. Together, these data indicate that Meflin may be a marker specific to tissue-resident PSCs and useful for studying their biology in both health and disease.journal articl