Description and measurement of competition in higher education markets: The example of Australia

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New Public Management am Beispiel der Hochschulen in Österreich und der Schweiz

Im Licht der Frage einer effektiven Reform öffentlicher Einrichtungen wie beispielsweise der Hochschulen lassen sich folgende Thesen möglicherweise aus den Interviewerhebungen für Österreich und der Schweiz ableiten: Die öffentliche und hochschulpolitische Aktivitätsdichte korreliert wie am Beispiel Österreichaufgezeigt nicht zwingend mit einer zunehmenden Ergebnisorientierung der Hochschulen. Dabei ist keine Aussage zu den tatsächlichen Leistungen erfolgt, sondern nur eine Auswertung eigener Einstellungsbewertungen von Hochschulangehörigen. Dies hängt insbesondere damit zusammen, dass Hochschulen in einem stark veränderlichen hochschulpolitischen Umfeld scheinbar zu einem eher managementthemen-orientierten und gleichzeitig eher außengerichteten Entwicklungsverhalten tendieren. Demgegenüber unterstützt ein relativ stabiles hochschulpolitisches Umfeld wie beispielsweise in der Schweiz die Umsetzung konkreter Verbesserungen in der operativen Leistungserstellung der Forschung und Lehre der Hochschulen, was beispielsweise konkret den akademischen Mitarbeitern zu Gute kommt. Dies sind allerdings zeitpunktbezogene und allenfalls kurzfristige Aussagen. Längerfristig könnte dieser festgestellte Störungsaufwand durch eine erhöhte Leistung im Wettbewerbsumfeld kompensiert werden. Als normative Aussage für die Verwaltungsmodernisierung öffentlicher Einrichtungen generell lässt sich mit einiger Vorsicht die These aufstellen, dass auch der Prozess der Verwaltungsmodernisierung selbst mehr inhaltlich und weniger in Richtung formaler Themen wie Wettbewerb, Autonomie und Rechtsform der Einrichtungen etc. orientiert sein sollte

New Public Management am Beispiel der Hochschulen in Österreich und der Schweiz

Im Licht der Frage einer effektiven Reform öffentlicher Einrichtungen wie beispielsweise der Hochschulen lassen sich folgende Thesen möglicherweise aus den Interviewerhebungen für Österreich und der Schweiz ableiten: Die öffentliche und hochschulpolitische Aktivitätsdichte korreliert wie am Beispiel Österreichaufgezeigt nicht zwingend mit einer zunehmenden Ergebnisorientierung der Hochschulen. Dabei ist keine Aussage zu den tatsächlichen Leistungen erfolgt, sondern nur eine Auswertung eigener Einstellungsbewertungen von Hochschulangehörigen. Dies hängt insbesondere damit zusammen, dass Hochschulen in einem stark veränderlichen hochschulpolitischen Umfeld scheinbar zu einem eher managementthemen-orientierten und gleichzeitig eher außengerichteten Entwicklungsverhalten tendieren. Demgegenüber unterstützt ein relativ stabiles hochschulpolitisches Umfeld wie beispielsweise in der Schweiz die Umsetzung konkreter Verbesserungen in der operativen Leistungserstellung der Forschung und Lehre der Hochschulen, was beispielsweise konkret den akademischen Mitarbeitern zu Gute kommt. Dies sind allerdings zeitpunktbezogene und allenfalls kurzfristige Aussagen. Längerfristig könnte dieser festgestellte Störungsaufwand durch eine erhöhte Leistung im Wettbewerbsumfeld kompensiert werden. Als normative Aussage für die Verwaltungsmodernisierung öffentlicher Einrichtungen generell lässt sich mit einiger Vorsicht die These aufstellen, dass auch der Prozess der Verwaltungsmodernisierung selbst mehr inhaltlich und weniger in Richtung formaler Themen wie Wettbewerb, Autonomie und Rechtsform der Einrichtungen etc. orientiert sein sollte. --

Logistikqualifikation und Gamification: Softwareentwicklung und Pilotierung der MARTINA-App

Logistics commands a huge variety of dynamic developments, driven by techno-logical, organizational as well as market changes. Within this dynamic environ-ment, logistics management demands a competent and flexible workforce, up-dated by current training and qualification tools. Publication of this research paper marks the midpoint of the project 'MARTINA', which does encompass the development of a smartphone-based edugaming-app as well as related efforts towards defining a topical map for ongoing qualification in logistics. While the latter has been the main focus of project work in the first two quarters of 2016, general game design as well as software prototype devel-opment have been taken on since. The prototype is as of 2017 being released in iterative steps, each delivering additional content/and or fixes to issues having been discovered during the user tests now running in parallel. This approach en-sures that the final edugaming-app will be relevant and useful for blue- and white-collar employees. Further benefit is the transferrability of game concepts to mul-tiple upcoming qualification topics. This research paper documents the process of iterative software development applied in the project, technical considerations with respect to conditions given by the android ecosystem as well as the realiza-tion of content-independent transferability. Section four contains extensive review and evaluation from an aesthetics and design studies perspective, while section five provides an outline of upcoming milestones in the project MARTINA (further topics and educational games)

Identifying Refractory AML Patients Using Rate of WBC Decline in Order to Reduce Length of Stay

Introduction: Acute Myeloid Leukemia (AML) is the most common acute leukemia in the United States. At diagnosis, these patients are admitted to begin induction chemotherapy and remain in the hospital throughout treatment. Response to therapy is assessed with bone marrow biopsy one month later. However, rate of white blood cell (WBC) and absolute blast count (ABC) decline can be useful in predicting bone marrow blast clearance and complete remission. Objective: Therefore, our goal is to identify AML patients refractory to induction therapy using rate of WBC, ABC, and ANC decline as prognostic markers in order to reduce length of stay. Methods: Combined retrospective/prospective chart review of AML patients seen by the Hematologic Malignancies team at Thomas Jefferson University Hospital between September 2017 and December 2018. We will use logistic regression to determine the association between rates of WBC, ABC, and ANC decline and the result of the first post-induction bone marrow biopsy. Results: At this time, over 700 patient charts have been reviewed and thus far, 13 patients have met the stringent inclusion criteria set by the research team. All patients who met our diagnostic and treatment criteria achieved clinical remission on follow up bone marrow biopsy. Discussion: Recruitment of additional patient charts is needed. Our research team has discussed potentially expanding our criteria to include patients further back in time from the last five years. More patient charts will allow us to more accurately compare rates of WBC decline between patients who do and do not achieve clinical remission

Canvass: a crowd-sourced, natural-product screening library for exploring biological space

NCATS thanks Dingyin Tao for assistance with compound characterization. This research was supported by the Intramural Research Program of the National Center for Advancing Translational Sciences, National Institutes of Health (NIH). R.B.A. acknowledges support from NSF (CHE-1665145) and NIH (GM126221). M.K.B. acknowledges support from NIH (5R01GM110131). N.Z.B. thanks support from NIGMS, NIH (R01GM114061). J.K.C. acknowledges support from NSF (CHE-1665331). J.C. acknowledges support from the Fogarty International Center, NIH (TW009872). P.A.C. acknowledges support from the National Cancer Institute (NCI), NIH (R01 CA158275), and the NIH/National Institute of Aging (P01 AG012411). N.K.G. acknowledges support from NSF (CHE-1464898). B.C.G. thanks the support of NSF (RUI: 213569), the Camille and Henry Dreyfus Foundation, and the Arnold and Mabel Beckman Foundation. C.C.H. thanks the start-up funds from the Scripps Institution of Oceanography for support. J.N.J. acknowledges support from NIH (GM 063557, GM 084333). A.D.K. thanks the support from NCI, NIH (P01CA125066). D.G.I.K. acknowledges support from the National Center for Complementary and Integrative Health (1 R01 AT008088) and the Fogarty International Center, NIH (U01 TW00313), and gratefully acknowledges courtesies extended by the Government of Madagascar (Ministere des Eaux et Forets). O.K. thanks NIH (R01GM071779) for financial support. T.J.M. acknowledges support from NIH (GM116952). S.M. acknowledges support from NIH (DA045884-01, DA046487-01, AA026949-01), the Office of the Assistant Secretary of Defense for Health Affairs through the Peer Reviewed Medical Research Program (W81XWH-17-1-0256), and NCI, NIH, through a Cancer Center Support Grant (P30 CA008748). K.N.M. thanks the California Department of Food and Agriculture Pierce's Disease and Glassy Winged Sharpshooter Board for support. B.T.M. thanks Michael Mullowney for his contribution in the isolation, elucidation, and submission of the compounds in this work. P.N. acknowledges support from NIH (R01 GM111476). L.E.O. acknowledges support from NIH (R01-HL25854, R01-GM30859, R0-1-NS-12389). L.E.B., J.K.S., and J.A.P. thank the NIH (R35 GM-118173, R24 GM-111625) for research support. F.R. thanks the American Lebanese Syrian Associated Charities (ALSAC) for financial support. I.S. thanks the University of Oklahoma Startup funds for support. J.T.S. acknowledges support from ACS PRF (53767-ND1) and NSF (CHE-1414298), and thanks Drs. Kellan N. Lamb and Michael J. Di Maso for their synthetic contribution. B.S. acknowledges support from NIH (CA78747, CA106150, GM114353, GM115575). W.S. acknowledges support from NIGMS, NIH (R15GM116032, P30 GM103450), and thanks the University of Arkansas for startup funds and the Arkansas Biosciences Institute (ABI) for seed money. C.R.J.S. acknowledges support from NIH (R01GM121656). D.S.T. thanks the support of NIH (T32 CA062948-Gudas) and PhRMA Foundation to A.L.V., NIH (P41 GM076267) to D.S.T., and CCSG NIH (P30 CA008748) to C.B. Thompson. R.E.T. acknowledges support from NIGMS, NIH (GM129465). R.J.T. thanks the American Cancer Society (RSG-12-253-01-CDD) and NSF (CHE1361173) for support. D.A.V. thanks the Camille and Henry Dreyfus Foundation, the National Science Foundation (CHE-0353662, CHE-1005253, and CHE-1725142), the Beckman Foundation, the Sherman Fairchild Foundation, the John Stauffer Charitable Trust, and the Christian Scholars Foundation for support. J.W. acknowledges support from the American Cancer Society through the Research Scholar Grant (RSG-13-011-01-CDD). W.M.W.acknowledges support from NIGMS, NIH (GM119426), and NSF (CHE1755698). A.Z. acknowledges support from NSF (CHE-1463819). (Intramural Research Program of the National Center for Advancing Translational Sciences, National Institutes of Health (NIH); CHE-1665145 - NSF; CHE-1665331 - NSF; CHE-1464898 - NSF; RUI: 213569 - NSF; CHE-1414298 - NSF; CHE1361173 - NSF; CHE1755698 - NSF; CHE-1463819 - NSF; GM126221 - NIH; 5R01GM110131 - NIH; GM 063557 - NIH; GM 084333 - NIH; R01GM071779 - NIH; GM116952 - NIH; DA045884-01 - NIH; DA046487-01 - NIH; AA026949-01 - NIH; R01 GM111476 - NIH; R01-HL25854 - NIH; R01-GM30859 - NIH; R0-1-NS-12389 - NIH; R35 GM-118173 - NIH; R24 GM-111625 - NIH; CA78747 - NIH; CA106150 - NIH; GM114353 - NIH; GM115575 - NIH; R01GM121656 - NIH; T32 CA062948-Gudas - NIH; P41 GM076267 - NIH; R01GM114061 - NIGMS, NIH; R15GM116032 - NIGMS, NIH; P30 GM103450 - NIGMS, NIH; GM129465 - NIGMS, NIH; GM119426 - NIGMS, NIH; TW009872 - Fogarty International Center, NIH; U01 TW00313 - Fogarty International Center, NIH; R01 CA158275 - National Cancer Institute (NCI), NIH; P01 AG012411 - NIH/National Institute of Aging; Camille and Henry Dreyfus Foundation; Arnold and Mabel Beckman Foundation; Scripps Institution of Oceanography; P01CA125066 - NCI, NIH; 1 R01 AT008088 - National Center for Complementary and Integrative Health; W81XWH-17-1-0256 - Office of the Assistant Secretary of Defense for Health Affairs through the Peer Reviewed Medical Research Program; P30 CA008748 - NCI, NIH, through a Cancer Center Support Grant; California Department of Food and Agriculture Pierce's Disease and Glassy Winged Sharpshooter Board; American Lebanese Syrian Associated Charities (ALSAC); University of Oklahoma Startup funds; 53767-ND1 - ACS PRF; PhRMA Foundation; P30 CA008748 - CCSG NIH; RSG-12-253-01-CDD - American Cancer Society; RSG-13-011-01-CDD - American Cancer Society; CHE-0353662 - National Science Foundation; CHE-1005253 - National Science Foundation; CHE-1725142 - National Science Foundation; Beckman Foundation; Sherman Fairchild Foundation; John Stauffer Charitable Trust; Christian Scholars Foundation)Published versionSupporting documentatio

Case Report: Concomitant Diagnosis of Plasma Cell Leukemia in Patient With JAK2 Positive Myeloproliferative Neoplasm.

Plasma cell dyscrasias and myeloproliferative neoplasms (MPN) are hematologic malignancies arising from two distinct hematopoietic cell lineages. They rarely occur concomitantly. Here, we report a case of a patient with a recent diagnosis of a JAK2 V617F positive MPN who presented with a new diagnosis of plasma cell leukemia. The patient had presented to the hospital with a leukocytosis predominantly comprised of plasma cells, followed by work-up involving peripheral blood flow cytometry, FISH analysis, and bone-marrow biopsy. FISH analysis was suggestive of a common progenitor cell for these distinct hematologic malignancies. To our knowledge, this case represents the second reported instance of a concomitant JAK2 positive MPN with primary plasma cell leukemia