Lülisamba torakaalosast pärinev primaarne angiosarkoom: haigusjuhu kirjeldus

Angiosarkoomid on agressiivsed ja haruldased vaskulaarsest endoteelist pärinevad pehmekoelised kasvajad. Kuigi need esinevad peamiselt pea- ja kaelapiirkonna nahal, võivad nad areneda ka mujal kehas. Üks haruldasematest angiosarkoomi lokalisatsioonidest on luulised struktuurid. Artiklis on kirjeldatud 63aastase mehe teekonda alates seljavalu tõttu perearsti poole pöördumisest kuni haruldase diagnoosi kinnitamiseni ja radiokemoteraapiajärgse jälgimiseni. Käsitletud haigusjuht näitab skeleti angiosarkoomide diagnostilisi ja terapeutilisi väljakutseid ning rõhutab multidistsiplinaarse lähenemisviisi tähtsust selliste haruldaste pahaloomuliste kasvajate ravis

Laser printing of silver-based micro-wires in ZrO2 substrate for smart implant applications

Smart implants are endowed with functions of sensing, actuating and control to solve problems that may arise during their use. The assembly of these functions along the implant surface is still a challenge. However, with the advent of 3D printing, it is possible to print on implants’ surface, communication channels or micro-antennas or even sensoric/actuating areas. Hence, a positive impact on the long-term performance of the implants (including hip, dental and knee) may be expected with the proposed approach. Despite titanium and Ti6Al4V titanium alloy are the standard choice for implants fabrication, 3Y-TZP (tetragonal 3% mol yttria-stabilized zirconia) has emerged as a ceramic material suitable to overcome titanium alloy problems, due to its numerous advantages. In this sense, this work is concerned with the ability of printing silver-based communication system in zirconia substrates by using laser technology. For this purpose, micro-cavities were created on ZrO2 substrate, where the silver powder was placed and sintered into them. Through the laser approach, silver-based wires with great quality and low resistivity values were achieved. The flexural strength results showed that the mechanical resistance of zirconia disks was affected by laser micro-wire printing, which decreased as the laser passage was performed. Based on the results, it is believed that the proposed approach seems to be effective for the manufacturing of implants with intrinsic capacities, useful for smart implant applications.This work has been supported by FCT (Fundação para a Ciência e Tecnologia - Portugal) in the scope of the projects UID/EEA/04436/ 2019 and NORTE-01-0145-FEDER-000018-HAMaBICo and Add.Additive_Manufacturing to Portuguese Industry_POCI-01-0247- FEDER-024533. Thank the CNPq (205791/2014-0) and CAPES for the financial support