The \u3cem\u3emir-51\u3c/em\u3e Family of MicroRNAs Functions in Diverse Regulatory Pathways in \u3cem\u3eCaenorhbditis elegans\u3c/em\u3e

The mir-51 family of microRNAs (miRNAs) in C. elegans are part of the deeply conserved miR-99/100 family. While loss of all six family members (mir-51-56) in C. elegans results in embryonic lethality, loss of individual mir-51 family members results in a suppression of retarded developmental timing defects associated with the loss of alg-1. The mechanism of this suppression of developmental timing defects is unknown. To address this, we characterized the function of the mir-51 family in the developmental timing pathway. We performed genetic analysis and determined that mir-51 family members regulate the developmental timing pathway in the L2 stage upstream of hbl-1. Loss of the mir-51 family member, mir-52, suppressed retarded developmental timing defects associated with the loss of let-7 family members and lin-46. Enhancement of precocious defects was observed for mutations in lin-14, hbl-1, and mir-48(ve33), but not later acting developmental timing genes. Interestingly, mir-51 family members showed genetic interactions with additional miRNA-regulated pathways, which are regulated by the let-7 and mir-35 family miRNAs, lsy-6, miR-240/786, and miR-1. Loss of mir-52 likely does not suppress miRNA-regulated pathways through an increase in miRNA biogenesis or miRNA activity. We found no increase in the levels of four mature miRNAs, let-7, miR-58, miR-62 or miR-244, in mir-52 or mir-52/53/54/55/56 mutant worms. In addition, we observed no increase in the activity of ectopic lsy-6 in the repression of a downstream target in uterine cells in worms that lack mir-52. We propose that the mir-51 family functions broadly through the regulation of multiple targets, which have not yet been identified, in diverse regulatory pathways in C. elegans

Dynamical Instabilities in a two-component Bose condensate in a 1d optical lattice

In this paper we carry out a stability analysis of the Bloch states of a two-component Bose-Einstein condensate confined to a 1d optical lattice. We consider two concrete systems: a mixture of two hyperfine states of Rubidium-87 and a mixture of Sodium-23 and Rubidium-87. The former is seen to exhibit similar phenomena to a single component condensate while the latter also suffers an instability to phase separation at small Bloch wave vectors. It is shown that sufficiently deep optical lattices can remove this latter instability, potentially allowing imiscible cold atoms species to be held in intimate contact and transported within an experimental system.Comment: 14 Pages, 9 figure

Quantitative test of a quantum theory for the resistive transition in a superconducting single-walled carbon nanotube bundle

The phenomenon of superconductivity depends on the coherence of the phase of the superconducting order parameter. The resistive transition in quasi-one-dimensional (quasi-1D) superconductors is broad because of a large phase fluctuation. We show that the resistive transition of a superconducting single-walled carbon nanotube bundle is in quantitative agreement with the Langer-Ambegaokar-McCumber-Halperin (LAMH) theory. We also demonstrate that the resistive transition below T^*_c = 0.89T_c0 is simply proportional to exp [-(3\beta T^*_c/T)(1-T/T^*_c)^3/2], where the barrier height has the same form as that predicted by the LAMH theory and T_c0 is the mean field superconducting transition temperature.Comment: 4 pages, 3 figure

The Mass of the Candidate Exoplanet Companion to HD136118 from Hubble Space Telescope Astrometry and High-Precision Radial Velocities

We use Hubble Space Telescope Fine Guidance Sensor astrometry and high-cadence radial velocities for HD136118 from the HET with archival data from Lick to determine the complete set of orbital parameters for HD136118b. We find an orbital inclination for the candidate exoplanet of i_{b} = 163.1 +- 3.0 deg. This establishes the actual mass of the object, M_{b} = 42^{+11}_{-18} MJup, in contrast to the minimum mass determined from the radial velocity data only, M_{b}sin{i} ~ 12 MJup. Therefore, the low-mass companion to HD 136118 is now identified as a likely brown dwarf residing in the "brown dwarf desert".Comment: 35 pages, 12 figures, 10 tables. Accepted for publication in Astrophysical Journa

Simulating quantum transport for a quasi-one-dimensional Bose gas in an optical lattice: the choice of fluctuation modes in the truncated Wigner approximation

We study the effect of quantum fluctuations on the dynamics of a quasi-one-dimensional Bose gas in an optical lattice at zero-temperature using the truncated Wigner approximation with a variety of basis sets for the initial fluctuation modes. The initial spatial distributions of the quantum fluctuations are very different when using a limited number of plane-wave (PW), simple-harmonic-oscillator (SHO) and self-consistently determined Bogoliubov (SCB) modes. The short-time transport properties of the Bose gas, characterized by the phase coherence in the PW basis are distinct from those gained using the SHO and SCB basis. The calculations using the SCB modes predict greater phase decoherence and stronger number fluctuations than the other choices. Furthermore, we observe that the use of PW modes overestimates the extent to which atoms are expelled from the core of the cloud, while the use of the other modes only breaks the cloud structure slightly which is in agreement with the experimental observations [1].Comment: 12 pages, 5 figure

Accurate M Dwarf Metallicities from Spectral Synthesis: A Critical Test of Model Atmospheres

We describe a method for accurately determining M dwarf metallicities with spectral synthesis based on abundance analyses of visual binary stars. We obtained high resolution, high signal-to-noise spectra of each component of five visual binary pairs at McDonald Observatory. The spectral types of the components range from F7 to K3 V for the primaries and M0.5 to M3.5 V for the secondaries. We have determined the metallicities of the primaries differentially with respect to the Sun by fitting synthetic spectra to Fe \textsc{i} line profiles in the observed spectra. In the course of our analysis of the M dwarf secondaries we have made significant improvements to the PHOENIX cool-star model atmospheres and the spectrum analysis code MOOG. Our analysis yields a RMS deviation of 0.11 dex in metallicity values between the binary pairs. We estimate the uncertainties in the derived stellar parameters for the M dwarfs to be 48 K, 0.10 dex, 0.12 dex, 0.15 km s$^{-1}$, and 0.20 km s$^{-1}$ for {T}$_{eff}$, log \textsl{g}, [M/H], $\xi$, and $\eta$ respectively. Accurate stellar evolutionary models are needed to progress further in the analysis of cool-star spectra; the new model atmospheres warrant recalculation of the evolutionary models.Comment: 39 pages, 6 tables, 8 figures, accepted to Ap

Quantum interference initiated super- and subradiant emission from entangled atoms

We calculate the radiative characteristics of emission from a system of entangled atoms which can have a relative distance larger than the emission wavelength. We develop a quantum multipath interference approach which explains both super- and subradiance though the entangled states have zero dipole moment. We derive a formula for the radiated intensity in terms of different interfering pathways. We further show how the interferences lead to directional emission from atoms prepared in symmetric W-states. As a byproduct of our work we show how Dicke's classic result can be understood in terms of interfering pathways. In contrast to the previous works on ensembles of atoms, we focus on finite numbers of atoms prepared in well characterized states.Comment: 10 pages, 8 figures, 2 Table

Magnetoroton scattering by phonons in the fractional quantum Hall regime

Motivated by recent phonon spectroscopy experiments in the fractional quantum Hall regime we consider processes in which thermally excited magnetoroton excitations are scattered by low energy phonons. We show that such scattering processes can never give rise to dissociation of magnetorotons into unbound charged quasiparticles as had been proposed previously. In addition we show that scattering of magnetorotons to longer wavelengths by phonon absorption is possible because of the shape of the magnetoroton dispersion curve and it is shown that there is a characteristic cross-over temperature above which the rate of energy transfer to the electron gas changes from an exponential (activated) to a power law dependence on the effective phonon temperature.Comment: LaTex document, 3 eps figures. submitted to Phys Rev