The APEX framework: prototyping of ubiquitous environments based on Petri Nets

The user experience of ubiquitous environments is a determining factor in their success. The characteristics of such systems must be explored as early as possible to anticipate potential user problems, and to reduce the cost of redesign. However, the development of early prototypes to be evaluated in the target environment can be disruptive to the ongoing system and therefore unacceptable. This paper reports on an ongoing effort to explore how model-based rapid prototyping of ubiquitous environments might be used to avoid actual deployment while still enabling users to interact with a representation of the system. The paper describes APEX, a framework that brings together an existing 3D Application Server with CPN Tools. APEX-based prototypes enable users to navigate a virtual world simulation of the envisaged ubiquitous environment. The APEX architecture and the proposed CPN-based modelling approach are described. An example illustrates their use.Fundação para a Ciência e a Tecnologia (FCT) - bolsa de doutoramento SFRH/BD/41179/200

Separating Agent-Functioning and Inter-Agent Coordination by Activated Modules: The DECOMAS Architecture

The embedding of self-organizing inter-agent processes in distributed software applications enables the decentralized coordination system elements, solely based on concerted, localized interactions. The separation and encapsulation of the activities that are conceptually related to the coordination, is a crucial concern for systematic development practices in order to prepare the reuse and systematic integration of coordination processes in software systems. Here, we discuss a programming model that is based on the externalization of processes prescriptions and their embedding in Multi-Agent Systems (MAS). One fundamental design concern for a corresponding execution middleware is the minimal-invasive augmentation of the activities that affect coordination. This design challenge is approached by the activation of agent modules. Modules are converted to software elements that reason about and modify their host agent. We discuss and formalize this extension within the context of a generic coordination architecture and exemplify the proposed programming model with the decentralized management of (web) service infrastructures

Integrating BDI agents with Agent-based simulation platforms

Agent-Based Models (ABMs) is increasingly being used for exploring and supporting decision making about social science scenarios involving modelling of human agents. However existing agent-based simulation platforms (e.g., SWARM, Repast) provide limited support for the simulation of more complex cognitive agents required by such scenarios. We present a framework that allows Belief-Desire Intention (BDI) cognitive agents to be embedded in an ABM system. Architecturally, this means that the "brains" of an agent can be modelled in the BDI system in the usual way, while the "body" exists in the ABM system. The architecture is exible in that the ABM can still have non-BDI agents in the simulation, and the BDI-side can have agents that do not have a physical counterpart (such as an organisation). The framework addresses a key integration challenge of coupling event-based BDI systems, with time-stepped ABM systems. Our framework is modular and supports integration off-the-shelf BDI systems with off-the-shelf ABM systems. The framework is Open Source, and all integrations and applications are available for use by the modelling community

CAMP-BDI: A Pre-emptive Approach for Plan Execution Robustness in Multiagent Systems

Abstract. Belief-Desire-Intention agents in realistic environments may face un-predictable exogenous changes threatening intended plans and debilitative failure effects that threaten reactive recovery. In this paper we present the CAMP-BDI (Capability Aware, Maintaining Plans) approach, where BDI agents utilize intro-spective reasoning to modify intended plans in avoidance of anticipated failure. We also describe an extension of this approach to the distributed case, using a de-centralized process driven by structured messaging. Our results show significant improvements in goal achievement over a reactive failure recovery mechanism in a stochastic environment with debilitative failure effects, and suggest CAMP-BDI offers a valuable complementary approach towards agent robustness.

Semantic Web Services for Multi-Agent Systems Interoperability

Agent-based technologies are often used including existing web services. The outputs of some services are also frequently used as inputs for other services, including other MAS. However, while agent-based technologies can be used to provide services, these are not described using the same semantic web technologies web services use, which makes it difficult to discover, invoke and compose them with web services seamlessly. In this paper, we analyse different agent-based technologies and how these can be described using extensions to OWL-S. Additionally, we propose an architecture that facilitates these services’ usage, where services of any kind can be registered and executed (semi-)automatically.The present work has been developed under the PIANISM Project (ANI|P2020 40125) and has received funding from FEDER Funds through NORTE2020 program and from National Funds through Fundação para a Ciência e a Tecnologia (FCT) under the project UID/EEA/00760/2019. Gabriel Santos is supported by national funds through FCT PhD studentship with reference SFRH/BD/118487/2016.info:eu-repo/semantics/publishedVersio

Providing integrated development environments for multi-agent systems

The computing industry has yet to take up agent technology as a new approach to software development. While other paradigms are supported by various tools, including generic IDEs, these are not well developed for agent-ware. Many agent platforms provide some form of IDE but these are platform-specific and are typically so tightly coupled to their agent platforms that they offer little re-use. There has been too little discussion about which tools an IDE should contain and few attempts to produce a generic IDE. In this paper, we identify two levels of abstraction requiring IDE tool support and draw on current research to categorise a set of generic tools for each level. We describe the reasons why existing MAS IDEs are coupled to their platforms and present an extendible software architecture which avoids this coupling. We build an IDE using this architecture and demonstrate its decoupling and extensibility by experimentation.</p

Congenital deficiency reveals critical role of ISG15 in skin homeostasis

Ulcerating skin lesions are manifestations of human ISG15 deficiency, a type I interferonopathy. However, chronic inflammation may not be their exclusive cause. We describe two siblings with recurrent skin ulcers that healed with scar formation upon corticosteroid treatment. Both had a homozygous nonsense mutation in the ISG15 gene, leading to unstable ISG15 protein lacking the functional domain. We characterized ISG15(-/-) dermal fibroblasts, HaCaT keratinocytes, and human induced pluripotent stem cell-derived vascular endothelial cells. ISG15-deficient cells exhibited the expected hyperinflammatory phenotype, but also dysregulated expression of molecules critical for connective tissue and epidermis integrity, including reduced collagens and adhesion molecules, but increased matrix metalloproteinases. ISG15(-/-) fibroblasts exhibited elevated ROS levels and reduced ROS scavenger expression. As opposed to hyperinflammation, defective collagen and integrin synthesis was not rescued by conjugation-deficient ISG15. Cell migration was retarded in ISG15(-/-) fibroblasts and HaCaT keratinocytes, but normalized under ruxolitinib treatment. Desmosome density was reduced in an ISG15(-/-) 3D epidermis model. Additionally, there were loose architecture and reduced collagen and desmoglein expression, which could be reversed by treatment with ruxolitinib/doxycycline/TGF-beta 1. These results reveal critical roles of ISG15 in maintaining cell migration and epidermis and connective tissue homeostasis, whereby the latter likely requires its conjugation to yet unidentified targets

Urban public health, a multidisciplinary approach

Urban environment is a highly complex interactive socio-physical system, with competing expectations and priorities. Public health interventions have always had a fundamental role in the control of diseases in cities. WHO considers urbanization as one of the key challenges for public health in the twenty-first century, since cities offer significant opportunities to improve public health if health-enhancing policies and actions are promoted. A multidisciplinary approach is required, but the basic differences existing between technical and health disciplines make the interaction difficult. The multidisciplinary collaboration is still at a very early stage of development, and needs to be further understood and planned. The author concludes stressing the need for a transversal training, but also for sharing knowledge, instruments and methods, involving all the actors in the planning process, to develop a real multidisciplinary approach

Architecting the IoT Paradigm: A Middleware for Autonomous Distributed Sensor Networks

Actualizing Internet of Things undoubtedly constitutes a major challenge of modern computing and is a promising next step in realizing the unification of all seamlessly interacting entities, either human users or participating machines, under a shared, coherent architecture. While it has now become common belief that the related solutions should be based on compatible network infrastructure employing widely accepted communication schemes, the specifics of the intermediate system that would act as global interface for all involved “things” are yet to be determined. A rising trend to define such machine-based entities is through cyber-physical systems, in terms of collaborating elements with physical input and output. Certainly, sensor networks constitute the most representative realization of such systems. Taking these issues and opportunities under consideration, this work proposes a bioinspired distributed architecture for an Internet of Things that exhibits self-organization properties to enable efficient interaction between entities modeled as cyber-physical systems, mainly focusing on sensor networks. Furthermore, a middleware has been implemented according to the proposed architecture, which serves the role of the backbone of this network as a multiagent and autonomous distributed system. The evaluation results demonstrate the self-optimization properties of the introduced scheme and indicate global network convergence

Externalisation and Internalization: A New Perspective on Agent Modularisation in Multi-Agent System Programming

Abstract—Agent modularisation is a main issue in agent and multi-agent system programming. Existing solutions typically propose some kinds of constructs – such as capabilities – to group and encapsulate in well-defined modules inside the agent different kinds of agent features, that depend on the architecture or model adopted—examples are goals, beliefs, intentions, skills. In this paper we introduce a further perspective, which can be considered complimentary to existing approaches, which accounts for externalizing some of such functionalities into the computational environment where agents are (logically) situated. In this perspective, agent modules are realised as suitably designed artifacts that agents can dynamically exploit as external tools to enhance their action repertoire and – more generally – their capability to execute tasks. Then, to let agent (and agent programmers) exploit such capabilities abstracting from the low-level mechanics of artifact management and use, we exploit the dual notion of internalization, which consists in dynamically consulting and automatically embedding high-level usage protocols described in artifact manuals as agent plans. The idea is discussed providing some practical examples of use, based on CArtAgO as technology for programming artifacts and Jason agent platform to program the agents. I