1,795 research outputs found

    Modifications et stabilité du phosphore échangeable d'un ferralsol ingéré par un ver géophage

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    L'un des paramètres des cinétiques de dilution isotopique du phosphore est modifié par l'ingestion, du ferralsol étudié, par le ver géophage #Pontoscolex corethrurus (#Glossoscolecidae, #Oligochaeta$). La concentation d'ions phosphate de la solution du sol et le compartiment d'ions immédiatement échangeables associé au sol sont nettement augmentés. Divers mécanismes pouvant expliquer ces modifications sont discutés. La minéralisation du phosphore organique s'effectue au profit des formes les plus rapidement échangeables. (Résumé d'auteur

    Produção e avaliação da qualidade do leite na microrregião de Castanhal.

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    Effects of spatial dispersion in near-field radiative heat transfer between two parallel metallic surfaces

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    We study the heat transfer between two parallel metallic semi-infinite media with a gap in the nanometer-scale range. We show that the near-field radiative heat flux saturates at distances smaller than the metal skin depth when using a local dielectric constant and investigate the origin of this effect. The effect of non-local corrections is analysed using the Lindhard-Mermin and Boltzmann-Mermin models. We find that local and non-local models yield the same heat fluxes for gaps larger than 2 nm. Finally, we explain the saturation observed in a recent experiment as a manifestation of the skin depth and show that heat is mainly dissipated by eddy currents in metallic bodies.Comment: Version without figures (8 figures in the complete version

    Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles.

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    Therapeutic engineered nanoparticles (NPs), including ultrasmall superparamagnetic iron oxide (USPIO) NPs, may accumulate in the lower digestive tract following ingestion or injection. In order to evaluate the reaction of human colon cells to USPIO NPs, the effects of non-stabilized USPIO NPs (NS-USPIO NPs), oleic-acid-stabilized USPIO NPs (OA-USPIO NPs), and free oleic acid (OA) were compared in human HT29 and CaCo2 colon epithelial cancer cells. First the biophysical characteristics of NS-USPIO NPs and OA-USPIO NPs in water, in cell culture medium supplemented with fetal calf serum, and in cell culture medium preconditioned by HT29 and CaCo₂ cells were determined. Then, stress responses of the cells were evaluated following exposure to NS-USPIO NPs, OA-USPIO NPs, and free OA. No modification of the cytoskeletal actin network was observed. Cell response to stress, including markers of apoptosis and DNA repair, oxidative stress and degradative/autophagic stress, induction of heat shock protein, or lipid metabolism was determined in cells exposed to the two NPs. Induction of an autophagic response was observed in the two cell lines for both NPs but not free OA, while the other stress responses were cell- and NP-specific. The formation of lipid vacuoles/droplets was demonstrated in HT29 and CaCo₂ cells exposed to OA-USPIO NPs but not to NS-USPIO NPs, and to a much lower level in cells exposed to equimolar concentrations of free OA. Therefore, the induction of lipid vacuoles in colon cells exposed to OA utilized as a stabilizer for USPIO NPs is higly amplified compared to free OA, and is not observed in the absence of this lipid in NS-USPIO NPs

    How Close is too Close? The Effect of a Non-Lethal Electric Shark Deterrent on White Shark Behaviour

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    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Sharks play a vital role in the health of marine ecosystems, but the potential threat that sharks pose to humans is a reminder of our vulnerability when entering the ocean. Personal shark deterrents are being marketed as the solution to mitigate the threat that sharks pose. However, the effectiveness claims of many personal deterrents are based on our knowledge of shark sensory biology rather than robust testing of the devices themselves, as most have not been subjected to independent scientific studies. Therefore, there is a clear need for thorough testing of commercially available shark deterrents to provide the public with recommendations of their effectiveness. Using a modified stereo-camera system, we quantified behavioural interactions between white sharks (Carcharodon carcharias) and a baited target in the presence of a commercially available, personal electric shark deterrent (Shark Shield Freedom7™). The stereo-camera system enabled an accurate assessment of the behavioural responses of C. carcharias when encountering a non-lethal electric field many times stronger than what they would naturally experience. Upon their first observed encounter, all C. carcharias were repelled at a mean (± std. error) proximity of 131 (± 10.3) cm, which corresponded to a mean voltage gradient of 9.7 (± 0.9) V/m. With each subsequent encounter, their proximity decreased by an average of 11.6 cm, which corresponded to an increase in tolerance to the electric field by an average of 2.6 (± 0.5) V/m per encounter. Despite the increase in tolerance, sharks continued to be deterred from interacting for the duration of each trial when in the presence of an active Shark Shield™. Furthermore, the findings provide no support to the theory that electric deterrents attract sharks. The results of this study provide quantitative evidence of the effectiveness of a non-lethal electric shark deterrent, its influence on the behaviour of C. carcharias, and an accurate method for testing other shark deterrent technologies

    Distribuição espacial das classes de degradação de pastagem em Marabá, PA e sua correlação com as classes de solo e relevo.

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    O presente trabalho teve como objetivo estudar a variabilidade espacial, por geoestatística, das classes de degradação de pastagens em Marabá, PA e verificar a correlação espacial com as classes de declividade e de solo

    Characterizing a new class of variability in GRS 1915+105 with simultaneous INTEGRAL/RXTE observations

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    We report on the analysis of 100 ks INTEGRAL observations of the Galactic microquasar GRS 1915+105. We focus on INTEGRAL Revolution number 48 when the source was found to exhibit a new type of variability as preliminarily reported in Hannikainen et al. (2003). The variability pattern, which we name ξ\xi, is characterized by a pulsing behaviour, consisting of a main pulse and a shorter, softer, and smaller amplitude precursor pulse, on a timescale of 5 minutes in the JEM-X 3-35 keV lightcurve. We also present simultaneous RXTE data. From a study of the individual RXTE/PCA pulse profiles we find that the rising phase is shorter and harder than the declining phase, which is opposite to what has been observed in other otherwise similar variability classes in this source. The position in the colour-colour diagram throughout the revolution corresponds to State A (Belloni et al. 2000) but not to any previously known variability class. We separated the INTEGRAL data into two subsets covering the maxima and minima of the pulses and fitted the resulting two broadband spectra with a hybrid thermal--non-thermal Comptonization model. The fits show the source to be in a soft state characterized by a strong disc component below ~6 keV and Comptonization by both thermal and non-thermal electrons at higher energies.Comment: Accepted for publication in A&A. 11 pages, 10 figures, 4 in colour. Original figures can be found at http://www.astro.helsinki.fi/~diana/grs1915_rev48. Author affiliations correcte

    A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes

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    Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs. Although airway epithelial cells represent an important target for infection, the respiratory epithelium is also composed of an elaborate network of dendritic cells (DCs) that are essential sentinels of the immune system, sensing pathogens and presenting foreign antigens to T lymphocytes. In this report, we show that in vitro infection by human coronavirus 229E (HCoV-229E) induces massive cytopathic effects in DCs, including the formation of large syncytia and cell death within only few hours. In contrast, monocytes are much more resistant to infection and cytopathic effects despite similar expression levels of CD13, the membrane receptor for HCoV-229E. While the differentiation of monocytes into DCs in the presence of granulocyte-macrophage colony-stimulating factor and interleukin-4 requires 5 days, only 24 h are sufficient for these cytokines to sensitize monocytes to cell death and cytopathic effects when infected by HCoV-229E. Cell death induced by HCoV-229E is independent of TRAIL, FasL, tumor necrosis factor alpha, and caspase activity, indicating that viral replication is directly responsible for the observed cytopathic effects. The consequence of DC death at the early stage of HCoV-229E infection may have an impact on the early control of viral dissemination and on the establishment of long-lasting immune memory, since people can be reinfected multiple times by HCoV-229E
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