3,876 research outputs found

    Philanthropy and Equity: The Case of South Africa

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    This paper explores the potential role for philanthropy to promote greater equity in South Africa. It also aims to stimulate further discussion and debate about how philanthropic resources can best contribute to a more just and equitable South Africa, and encourage others engaged in philanthropy elsewhere in the world to reflect on South Africa's experience

    Employment equity in Canada and South Africa: a comparative review

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    The South African Government has sought to redress the historical legacy of workplace discrimination by introducing the Employment Equity Act (1998), which was largely modeled on the Canadian Employment Equity Act. Although there is very little comparative information between South Africa and Canada, we fill this gap by reviewing the literature in both countries, highlighting common features of the legislation, discussing the effectiveness of legislation in both countries as well as the progress made by the designated groups covered by the legislation. This paper provides a background on the rationale for employment equity and associated human resource management policies in both Canada and South Africa. The analysis is largely based on institutional theories of organizations. Our evaluation provides overall conclusions for policy makers and organizational leaders, taking into consideration socio-historical, political, and demographic differences between the jurisdictions. Issues include top management commitment, organizational culture, Black economic empowerment, and diversity policies and practice

    Effects of landscape gradients on wetland vegetation communities: information for large-scale restoration

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    Projects of the scope of the restoration of the Florida Everglades require substantial information regarding ecological mechanisms, and these are often poorly understood. We provide critical base knowledge for Everglades restoration by characterizing the existing vegetation communities of an Everglades remnant, describing how present and historic hydrology affect wetland vegetation community composition, and documenting change from communities described in previous studies. Vegetation biomass samples were collected along transects across Water Conservation Area 3A South (3AS)

    A Survey of the Management and Development of Captive African Elephant (\u3cem\u3eLoxodonta africana\u3c/em\u3e) Calves: Birth to Three Months of Age

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    We used four surveys to collect information about the birth, physical growth, and behavioral development of 12 African elephant calves born in captivity. The management of the birth process and neonatal care involved a variety of standard procedures. All of the calves were born at night, between 7PM and 7AM. The calves showed a systematic progression in behavioral and physical development, attaining developmental milestones at least a quickly as calves in situ. This study emphasized birth-related events, changes in the ways that calves used their trunks, first instances of behaviors, and interactions of the calves with other, usually adult, elephants. Several behaviors, such as the dam covering her calf with hay and the calf sucking its own trunk, were common in the captive situation and have been observed in situ. Overall, the behaviors of the calves resembled those observed for African elephant calves in situ. These data should help in the management of African elephants under human care by providing systematic reference values for the birth and development of elephant calves

    Control of lipid organization and actin assembly during clathrin-mediated endocytosis by the cytoplasmic tail of the rhomboid protein Rbd2.

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    Clathrin-mediated endocytosis (CME) is facilitated by a precisely regulated burst of actin assembly. PtdIns(4,5)P2 is an important signaling lipid with conserved roles in CME and actin assembly regulation. Rhomboid family multipass transmembrane proteins regulate diverse cellular processes; however, rhomboid-mediated CME regulation has not been described. We report that yeast lacking the rhomboid protein Rbd2 exhibit accelerated endocytic-site dynamics and premature actin assembly during CME through a PtdIns(4,5)P2-dependent mechanism. Combined genetic and biochemical studies showed that the cytoplasmic tail of Rbd2 binds directly to PtdIns(4,5)P2 and is sufficient for Rbd2's role in actin regulation. Analysis of an Rbd2 mutant with diminished PtdIns(4,5)P2-binding capacity indicates that this interaction is necessary for the temporal regulation of actin assembly during CME. The cytoplasmic tail of Rbd2 appears to modulate PtdIns(4,5)P2 distribution on the cell cortex. The syndapin-like F-BAR protein Bzz1 functions in a pathway with Rbd2 to control the timing of type 1 myosin recruitment and actin polymerization onset during CME. This work reveals that the previously unstudied rhomboid protein Rbd2 functions in vivo at the nexus of three highly conserved processes: lipid regulation, endocytic regulation, and cytoskeletal function

    Co-GISAXS as a New Technique to Investigate Surface Growth Dynamics

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    Detailed quantitative measurement of surface dynamics during thin film growth is a major experimental challenge. Here X-ray Photon Correlation Spectroscopy with coherent hard X-rays is used in a Grazing-Incidence Small-Angle X-ray Scattering (i.e. Co-GISAXS) geometry as a new tool to investigate nanoscale surface dynamics during sputter deposition of a-Si and a-WSi2_2 thin films. For both films, kinetic roughening during surface growth reaches a dynamic steady state at late times in which the intensity autocorrelation function g2g_2(q,t) becomes stationary. The g2g_2(q,t) functions exhibit compressed exponential behavior at all wavenumbers studied. The overall dynamics are complex, but the most surface sensitive sections of the structure factor and correlation time exhibit power law behaviors consistent with dynamical scaling.Comment: 32 pages, 12 figure

    Dust Destruction Rates and Lifetimes in the Magellanic Clouds

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    The nature, composition, abundance, and size distribution of dust in galaxies is determined by the rate at which it is created in the different stellar sources and destroyed by interstellar shocks. Because of their extensive wavelength coverage, proximity, and nearly face-on geometry, the Magellanic Clouds (MCs) provide a unique opportunity to study these processes in great detail. In this paper we use the complete sample of supernova remnants (SNRs) in the MCs to calculate the lifetime and destruction efficiencies of silicate and carbon dust in these galaxies. We find dust lifetimes of 22 +- 13 Myr (30 +- 17 Myr) for silicate (carbon) grains in the LMC, and 54 +- 32 Myr (72 +- 43 Myr) for silicate (carbon) grains in the SMC. The significantly shorter lifetimes in the MCs, as compared to the Milky Way, are explained as the combined effect of their lower total dust mass, and the fact that the dust-destroying isolated SNe in the MCs seem to be preferentially occurring in regions with higher than average dust-to-gas (D2G) mass ratios. We also calculate the supernova rate and the current star formation rate in the MCs, and use them to derive maximum dust injection rates by asymptotic giant branch stars and core collapse supernovae. We find that the injection rates are an order of magnitude lower than the dust destruction rates by the SNRs. This supports the conclusion that, unless the dust destruction rates have been considerably overestimated, most of the dust must be reconstituted from surviving grains in dense molecular clouds. More generally, we also discuss the dependence of the dust destruction rate on the local D2G mass ratio, the ambient gas density and metallicity, as well as the application of our results to other galaxies and dust evolution models.Comment: 15 pages, 8 figures, 5 tables, accepted to Ap

    The Lives Saved Tool (LiST) as a model for diarrhea mortality reduction

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    BACKGROUND: Diarrhea is a leading cause of morbidity and mortality among children under five years of age. The Lives Saved Tool (LiST) is a model used to calculate deaths averted or lives saved by past interventions and for the purposes of program planning when costly and time consuming impact studies are not possible. DISCUSSION: LiST models the relationship between coverage of interventions and outputs, such as stunting, diarrhea incidence and diarrhea mortality. Each intervention directly prevents a proportion of diarrhea deaths such that the effect size of the intervention is multiplied by coverage to calculate lives saved. That is, the maximum effect size could be achieved at 100% coverage, but at 50% coverage only 50% of possible deaths are prevented. Diarrhea mortality is one of the most complex causes of death to be modeled. The complexity is driven by the combination of direct prevention and treatment interventions as well as interventions that operate indirectly via the reduction in risk factors, such as stunting and wasting. Published evidence is used to quantify the effect sizes for each direct and indirect relationship. Several studies have compared measured changes in mortality to LiST estimates of mortality change looking at different sets of interventions in different countries. While comparison work has generally found good agreement between the LiST estimates and measured mortality reduction, where data availability is weak, the model is less likely to produce accurate results. LiST can be used as a component of program evaluation, but should be coupled with more complete information on inputs, processes and outputs, not just outcomes and impact. SUMMARY: LiST is an effective tool for modeling diarrhea mortality and can be a useful alternative to large and expensive mortality impact studies. Predicting the impact of interventions or comparing the impact of more than one intervention without having to wait for the results of large and expensive mortality studies is critical to keep programs focused and results oriented for continued reductions in diarrhea and all-cause mortality among children under five years of age
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