2,355 research outputs found
Two-point theory for the differential self-interrogation Feynman-alpha method
A Feynman-alpha formula has been derived in a two region domain pertaining
the stochastic differential self-interrogation (DDSI) method and the
differential die-away method (DDAA). Monte Carlo simulations have been used to
assess the applicability of the variance to mean through determination of the
physical reaction intensities of the physical processes in the two domains.
More specifically, the branching processes of the neutrons in the two regions
are described by the Chapman - Kolmogorov equation, including all reaction
intensities for the various processes, that is used to derive a variance to
mean relation for the process. The applicability of the Feynman-alpha or
variance to mean formulae are assessed in DDSI and DDAA of spent fuel
configurations.Comment: 15 pages, 5 figures. Submitted to EPJ Plu
Target of rapamycin (TOR) mediates the transduction of nutritional signals into juvenile hormone production
Anautogeny is a reproductive strategy by which females do not reproduce until they feed. Therefore, nutritional signals must inform the reproductive tissues, and cells that the organism has reached a nutritional status suitable for triggering reproductive processes. One of the possible pathways involved in anautogeny is the >target of rapamycin> (TOR) pathway, which has been described as connecting the nutritional status with growth, proliferation, and cancer. The German cockroach, Blattella germanica, is an anautogenous species whose vitellogenesis is governed by juvenile hormone. In the present report, we describe the cloning of TOR cDNA from B. germanica (BgTOR). Expression studies showed that BgTOR is expressed in adult female corpora allata and fat body. BgTOR knockdown using systemic RNAi in vivo produced a severe inhibition of juvenile hormone synthesis in adult female corpora allata, together with a reduction of mRNA levels corresponding to 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase-1, HMG-CoA synthase-2, and HMG-CoA reductase. In addition, there was a reduction of vitellogenin mRNA in the fat body, and ovaries did not grow. Analysis of TOR expression in corpora allata of fed and starved females suggested that TOR is not regulated at the transcriptional level. Nevertheless, there was a reduction in HMG-CoA synthases and reductase mRNA in corpora allata (but not in the fat body) of starved females, together with a dramatic reduction of juvenile hormone production and ovary development. Taken together, our results indicate that TOR knockdown mimics starvation in terms of corpora allata activity, and suggest that nutritional signals that activate juvenile hormone biosynthesis and vitellogenin production are mediated by the TOR pathway. © 2009 by The American Society for Biochemistry and Molecular Biology, Inc.This work was supported by the Spanish Ministry of Science and Technology (Projects BFU2006-01090 (to J. L. M.) and AGL2005-00773 and CGL2008-03517/BOS (to X. B.). The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.Peer Reviewe
Fluxtube model atmospheres and Stokes V zero-crossing wavelengths
First results of the inversion of Stokes I and V profiles from plage regions
near disk center are presented. Both low and high spatial resolution spectra of
FeI 6301.5 and FeI 6302.5 A obtained with the Advanced Stokes Polarimeter (ASP)
have been considered for analysis. The thin flux tube approximation,
implemented in an LTE inversion code based on response functions, is used to
describe unresolved magnetic elements. The code allows the simultaneous and
consistent inference of all atmospheric quantities determining the radiative
transfer with the sole assumption of hydrostatic equilibrium. By considering
velocity gradients within the tubes we are able to match the full ASP Stokes
profiles. The magnetic atmospheres derived from the inversion are characterized
by the absence of significant motions in high layers and strong velocity
gradients in deeper layers. These are essential to reproduce the asymmetries of
the observed profiles. Our scenario predicts a shift of the Stokes V
zero-crossing wavelengths which is indeed present in observations made with the
Fourier Transform Spectrometer.Comment: To appear in ApJ Letters (1997) (in press
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Significant Protection from Infection and AIDS Progression After Gastrointestinal and Oral Vaccinations, Respectively, with a SIV DNA/rMVA Vaccine
Milne-Eddington inversion of the Fe I line pair at 630~nm
The iron lines at 630.15 and 630.25 nm are often used to determine the
physical conditions of the solar photosphere. A common approach is to invert
them simultaneously under the Milne-Eddington approximation. The same
thermodynamic parameters are employed for the two lines, except for their
opacities, which are assumed to have a constant ratio. We aim at investigating
the validity of this assumption, since the two lines are not exactly the same.
We use magnetohydrodynamic simulations of the quiet Sun to examine the behavior
of the ME thermodynamic parameters and their influence on the retrieval of
vector magnetic fields and flow velocities. Our analysis shows that the two
lines can be coupled and inverted simultaneously using the same thermodynamic
parameters and a constant opacity ratio. The inversion of two lines is
significantly more accurate than single-line inversions because of the larger
number of observables.Comment: Accepted for publication in Astronomy and Astrophysics (Research
Note
Temporal evolution of the Evershed flow in sunspots. II. Physical properties and nature of Evershed clouds
Context: Evershed clouds (ECs) represent the most conspicuous variation of
the Evershed flow in sunspot penumbrae. Aims: We determine the physical
properties of ECs from high spatial and temporal resolution spectropolarimetric
measurements. Methods: The Stokes profiles of four visible and three infrared
spectral lines are subject to inversions based on simple one-component models
as well as more sophisticated realizations of penumbral flux tubes embedded in
a static ambient field (uncombed models). Results: According to the
one-component inversions, the EC phenomenon can be understood as a perturbation
of the magnetic and dynamic configuration of the penumbral filaments along
which these structures move. The uncombed inversions, on the other hand,
suggest that ECs are the result of enhancements in the visibility of penumbral
flux tubes. We conjecture that the enhancements are caused by a perturbation of
the thermodynamic properties of the tubes, rather than by changes in the vector
magnetic field. The feasibility of this mechanism is investigated performing
numerical experiments of thick penumbral tubes in mechanical equilibrium with a
background field. Conclusions: While the one-component inversions confirm many
of the properties indicated by a simple line parameter analysis (Paper I of
this series), we tend to give more credit to the results of the uncombed
inversions because they take into account, at least in an approximate manner,
the fine structure of the penumbra.Comment: Accepted for publication in A&
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