13,915 research outputs found
PTSD in the 20th Century American Military: Its Diagnosis, Effects, Treatment, and Management, With a Focus on the Vietnam War
Soldiers have been affected by PTSD for as long as war has existed. The American Military in the twentieth century is no exception. PTSD did not become a diagnosable disease until 1980, and before then it was misdiagnosed as different anxiety disorders and neuroses. Symptoms, treatment options, and long-term affects of PTSD are also discussed. Though other other wars in which America was involved are mentioned, those that receive a more thorough analysis are World War II, the Korean War, and the Vietnam War. Although PTSD is an increasing problem in modern times for those involved in military conflicts, there are effective therapy and treatment options available for the modern soldier that were not there in times past
Web 2.0 Projects at Warwick University Library
About 2 years ago at Warwick our senior managers encouraged Academic Support staff to really explore web 2.0 technologies and find out if anything particularly lent itself to supporting library work or marketing. We were given free reign to find out what worked and what suited the library, and what didn’t. The following brief overviews cover only four of the projects that have been running since then. We have also investigated much more, including Twitter, Google Documents, wiki reading lists, You-Tube and more, but we couldn’t possibly fit it all in here. The brief articles below are just to give a taste of the kind of projects we have worked on. There are many more members of staff involved and many more web 2.0 adventures underway..
Turnaround Time Between ILLiad’s Odyssey and Ariel Delivery Methods: A Comparison
Interlibrary loan departments are frequently looking for ways to reduce turnaround time. The advent of electronic delivery in the past decade has greatly reduced turnaround time for articles, but recent developments in this arena have the potential to decrease that time even further. The ILLiad ILL management system has an electronic delivery component, Odyssey, with a Trusted Sender setting that allows articles to be sent to patrons without borrowing staff intervention, provided the lending library is designated as a Trusted Sender, or this feature is enabled for all lenders. Using the tracking data created by the ILLiad management system, the turnaround time for two delivery methods, Ariel and Odyssey, was captured for two different academic institutions. With the Trusted Sender setting turned on, Odyssey delivery was faster than Ariel for the institutions studied
Quantitative chemical analysis of perovskite deposition using spin coating
Lead and halide ion compositions of spin coated organo-lead halide perovskite films have been quantified
using ion chromatography (IC) and atomic absorption spectroscopy (AAS) using perovskite films manufactured
by 5 different researchers (3 replicates per treatment) to monitor variability between researchers
and individual researcher reproducibility. Planar and mesoporous TiO2-coated glass substrates have
been studied along with tribromide (CH3NH3PbBr3), triiodide (CH3NH3PbI3) and mixed halide
(CH3NH3PbI3�xClx) perovskite films. The data show low yields of spin coated perovskite material (ca.
1%) and preferential deposition of I� over Cl� in mixed halide films
An assessment of warm fog: Nucleation, control, and recommended research
A state-of-the-art survey is given of warm fog research which has been performed up to, and including, 1974. Topics covered are nucleation, growth, coalescence, fog structures and visibility, effects of surface films, drop size spectrum, optical properties, instrumentation, liquid water content, condensation nuclei. Included is a summary of all reported fog modification experiments. Additional data is provided on air flow, turbulence, a summary of recommendations on instruments to be developed for determining turbulence, air flow, etc., as well as recommendations of various fog research tasks which should be performed for a better understanding of fog microphysics
Recovering a lost baseline: missing kelp forests from a metropolitan coast
© 2008 AuthorThere is concern about historical and continuing loss of canopy-forming algae across the world’s temperate coastline. In South Australia, the sparse cover of canopy-forming algae on the Adelaide metropolitan coast has been of public concern with continuous years of anecdotal evidence culminating in 2 competing views. One view considers that current patterns existed before the onset of urbanisation, whereas the alternate view is that they developed after urbanisation. We tested hypotheses to distinguish between these 2 models, each centred on the reconstruction of historical covers of canopies on the metropolitan coast. Historically, the metropolitan sites were indistinguishable from contemporary populations of reference sites across 70 km (i.e. Gulf St. Vincent), and could also represent a random subset of exposed coastal sites across 2100 km of the greater biogeographic province. Thus there was nothing ‘special’ about the metropolitan sites historically, but today they stand out because they have sparser covers of canopies compared to equivalent locations and times in the gulf and the greater province. This is evidence of wholesale loss of canopy-forming algae (up to 70%) on parts of the Adelaide metropolitan coast since major urbanisation. These findings not only set a research agenda based on the magnitude of loss, but they also bring into question the logic that smaller metropolitan populations of humans create impacts that are trivial relative to that of larger metropolitan centres. Instead, we highlight a need to recognise the ecological context that makes some coastal systems more vulnerable or resistant to increasing human-domination of the world’s coastlines. We discuss challenges to this kind of research that receive little ecological discussion, particularly better leadership and administration, recognising that the systems we study out-live the life spans of individual research groups and operate on spatial scales that exceed the capacity of single research providers.Sean D. Connell, Bayden D. Russell, David J. Turner, Scoresby A. Shepherd, Timothy Kildea, David Miller, Laura Airoldi, Anthony Cheshir
Myosin light chain kinase plays a role in the regulation of epithelial cell survival
Myosin II activation is essential for stress fiber and focal adhesion formation, and is implicated in integrin-mediated signaling events. In this study we investigated the role of acto-myosin contractility, and its main regulators, i.e. myosin light chain kinase (MLCK) and Rho-kinase (ROCK) in cell survival in normal and Ras-transformed MCF-10A epithelial cells. Treatment of cells with pharmacological inhibitors of MLCK (ML-7 and ML-9), or expression of dominant-negative MLCK, led to apoptosis in normal and transformed MCF-10A cells. By contrast, treatment of cells with a ROCK inhibitor (Y-27632) did not induce apoptosis in these cells. Apoptosis following inhibition of myosin II activation by MLCK is probably meditated through the death receptor pathway because expression of dominant-negative FADD blocked apoptosis. The apoptosis observed after MLCK inhibition is rescued by pre-treatment of cells with integrin-activating antibodies. In addition, this rescue of apoptosis is dependent on FAK activity, suggesting the participation of an integrin-dependent signaling pathway. These studies demonstrate a newly discovered role for MLCK in the generation of pro-survival signals in both untransformed and transformed epithelial cells and supports previous work suggesting distinct cellular roles for Rho-kinase- and MLCK-dependent regulation of myosin II
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