14,159 research outputs found

    Testing goodwill: Conflict and co-operation in new product development networks

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    Network forms are often seen as models of organisational flexibility, promoting the building of trust and exchange of information between different business functions while offering both cost savings and reductions in the uncertainties usually associated with innovation. Both internal and external networks have been identified as key elements in the collaborative development of new products. The actual process of network building and ongoing network management is not well researched, although the existing literature highlights difficulties for organisations attempting to maintain active product development networks. This article examines the development and management of such a network in the defence industry and focuses on network building processes in terms of the interactions between the individuals involved. This network has endured and evolved over many years despite a series of conflicts. One of the key findings is that the effective functioning of the overall network is closely allied to established processes within the two participating firms

    Generalised knot groups distinguish the square and granny knots (with an appendix by David Savitt)

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    Given a knot K we may construct a group G_n(K) from the fundamental group of K by adjoining an nth root of the meridian that commutes with the corresponding longitude. These "generalised knot groups" were introduced independently by Wada and Kelly, and contain the fundamental group as a subgroup. The square knot SK and the granny knot GK are a well known example of a pair of distinct knots with isomorphic fundamental groups. We show that G_n(SK) and G_n(GK) are non-isomorphic for all n>1. This confirms a conjecture of Lin and Nelson, and shows that the isomorphism type of G_n(K), n>1, carries more information about K than the isomorphism type of the fundamental group. An appendix by David Savitt contains some results on representations of the trefoil group in PSL(2,p) that are needed for the proof.Comment: 25 pages, 5 figures, to appear in JKTR. v3: example of the target groups added; slight correction to the construction of the target groups; references updated; some changes to notation. v2: section 4.2 expanded to give overview of proo

    Genetic Family and Stock Type Influence Simulated Loblolly Pine Yields from Wet Sites

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    Planting adapted families or a bulked seedlot of bare-root and container-grown-seedlings of loblolly pine (Pinus taeda L) were contrasted as cost effective alternatives for regenerating Arkansas\u27 wet sites. Survival data from two wet sites were used to simulate 15 years of growth. Containerized seedlings provided 17% greater survival than bare-root seedlings, but yielded a lower present net worth than bare-root seedlings. Planting families adapted to excessive moisture provided 7% greater survival and yielded a greater present net worth than planting a bulked seedlot consisting of adapted and poorly adapted families

    An aid to the development of Botswana's resources: Section on hydrology

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    The author has identified the following significant results. It is proved that FCC's can be used for a simple estimate of the total evaportranspiring area of the Okavango Delta, sufficiently accurate for preliminary inputs for the development of mathematical model of the surface hydrology of the delta. The color coded matrix has shown as interesting inverse correlation with an array on the same grid prepared by ecologists from air photography study, for percent liable to flood

    Evidence of epistasis between Interleukin-1 and Selenoprotein-S with susceptibility to rheumatoid arthritis

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    Objective: Selenoprotein-S (SELS) is involved in the stress response within the endoplasmic reticulum (ER) and inflammation. Recently, promoter variants in the SELS gene were shown to be associated with plasma levels of interleukin (IL)6, IL1β and tumour necrosis factor (TNF). It was hypothesised that these variants could influence rheumatoid arthritis (RA) susceptibility and may interact with functional single nucleotide polymorphisms (SNPs) in the genes for IL1, IL6 and TNF. Methods: Genotyping was performed in 988 unrelated healthy controls and 965 patients with RA. Stratified analysis was used to test for interactions. Single gene effects and evidence of epistasis were investigated using the Mantel–Haenszel (M–H) test and the linkage disequilibrium (LD)-based statistic. Results: No association of SELS −105 genotype and RA susceptibility was detected. Stratification of SELS −105 genotypes by IL1 −511 genotypes showed that the disease risk (comparing AA/GA to GG at the SELS −105 locus) in individuals with the GG/AG genotype at the IL1β −511 locus was significantly lower than that in individuals having the AA genotype at the IL1β −511 locus (odds ratio (OR): 0.9 and 2.3, respectively; p = 0.004 by M–H test). Significant epistasis was also detected using the LD-based statistic (p = <0.001). No interaction was observed between SELS −105 and IL6 or TNF variants. Conclusion: Our results reveal evidence of strong epistasis in two genes in the IL1 production pathway and highlight the potential importance of gene–gene interactions in the pathogenesis of RA

    A comparative study of the surface glaze characteristics of concrete treated with CO2 and high power diode lasers. Part II: mechanical, chemical and physical properties

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    The hardened ordinary Portland cement (OPC) surface layer of concrete which was glazed using a CO2 and a high power diode laser (see Part I of this paper) has been tested in order to determine the mechanical, chemical and physical characteristics of the glazes. The work showed that the generation of the surface glazes resulted in improved mechanical, chemical and physical properties over the untreated OPC surface of concrete. However, differences in the performance of the CO2 and HPDL generated glazes were observed. These are believed to be due to the differences in the morphology and microstructure of the glazes generated as a result of the differing beam absorption characteristics of the two lasers. Life assessment testing revealed that the laser glazed OPC surfaces effected an increase in actual wear life of 1.3 to 17.7 times over the untreated OPC surface of concrete depending upon the corrosive environment

    An aid to the development of Botswana's resources

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    There are no author-identified significant results in this report

    First report of Metarhizium anisopliae IP 46 pathogenicity in adult Anopheles gambiae s.s. and An. arabiensis (Diptera; Culicidae).

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    The entomopathogenic fungus Metarhizium anisopliae isolate IP 46, originating from a soil sample collected in 2001 in the Cerrado of Central Brazil, was tested for its ability to reduce the survival of adult male and female Anopheles gambiae s.s. and An. arabiensis mosquitoes. A 6-h exposure to the fungus coated on test paper at a concentration of 3.3 x 106 conidia cm-2 reduced the daily survival of both mosquito species (HR = 3.14, p < 0.001), with higher risk of dying in An. gambiae s.s relative to An. arabiensis (HR = 1.38, p < 0.001). Fungal sporulation was observed in >95% of mosquito cadavers in the treatment groups. The results indicate that M. anisopliae IP 46 has the potential to be a bio-control agent for African malaria vector species, and is a suitable candidate for further research and development
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