60 research outputs found

    Problems of Russia’s Integration into the Legal Framework of Europe

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    In the article the authors examine the issues of legal interaction between Russia and the European Court of Human Rights on the basis of generalization of empirical results obtained during the sociological survey of groups of respondents of different professional backgrounds. The blocks of legislative and law enforcement problems that need to be resolved are highlighted. The conclusion is made about the need to transform and unify the existing Russian legislation and law enforcement practices, relying on the practice of the European Court of Human Rights and the practice of national courts. Legislative proposals and law enforcement recommendations are formulated based on the results of the study. In the article, on the basis of generalization of empirical results obtained during the sociological survey of groups of respondents with different professional backgrounds, the authors examine the issues of Russia’s interaction with the European Court of Human Rights. The blocks of legislative and law enforcement problems that need to be resolved are highlighted. Drawing on the practice of the European Court of Human Rights and the practice of national courts, it is concluded that it is necessary to transform and unify the existing Russian legislation and law enforcement practice. The results of the study formulate legislative proposals and enforcement recommendations.     Keywords: justice, civil proceedings, Convention for the Protection of Human Rights and Fundamental Freedoms, European Court of Human Rights, law enforcement, case la

    Comparative evaluation of the efficacy and safety of intra-articular administration of hyaluronic acid and glucocorticoids in the complex therapy of osteoarthritis

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    Improving the treatment of knee (KN) osteoarthritis (OA) remains an urgent problem.Objective: to compare the efficacy and tolerability of intra-articular (i/a) administration of long-acting glucocorticoids (GCs) and Armaviscon®Forte and Armaviscon®Platinum hyaluronates in patients with knee OA.Material and methods. From November 2019 to April 2022, we examined and treated 60 patients (26 men and 34 women, mean age 41.32±3.71 years) suffering from primary KN OA. Study participants were randomly divided into three groups of 20 patients each. In the 1st group, a longacting GCs in combination with a local anesthetic was administered once i/a into the KN, in the 2nd – Armaviscon®Forte 2.3%, and in the 3rd – Armaviscon®Platinum 3%.Patients were examined at baseline, on the 14th and 60th day after a single injection of the drug. The intensity of pain was assessed on a visual analog scale (VAS), the Lequesne index, the KOOS, WOMAC, and EQ-5D questionnaires were used. When studying tolerability, the number of adverse reactions (ARs) was taken into account.Results. By the end of the observation period in the study groups, there was a decrease in the severity of pain and an increase in functionality with positive dynamics of the Lequesne and WOMAC indices. Both hyaluronic acid drugs had a positive effect on the functional state of the joints according to KOOS, improved the quality of life according to EQ-5D. The need for non-steroidal anti-inflammatory drugs in patients of the 2nd and 3rd groups decreased down to their complete cancellation. No adverse events requiring discontinuation of therapy have been reported. The advantage of i/a administration of hyaluronates in comparison with long-acting GCs was shown.Conclusion. In real clinical practice, in patients with symptomatic OA, i/a administration of hyaluronates allows obtaining more favorable results than the use of long-acting HA

    Сравнительная оценка эффективности и безопасности внутрисуставного введения препаратов гиалуроновой кислоты и глюкокортикоидов в комплексной терапии остеоартрита

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    Improving the treatment of knee (KN) osteoarthritis (OA) remains an urgent problem.Objective: to compare the efficacy and tolerability of intra-articular (i/a) administration of long-acting glucocorticoids (GCs) and Armaviscon®Forte and Armaviscon®Platinum hyaluronates in patients with knee OA.Material and methods. From November 2019 to April 2022, we examined and treated 60 patients (26 men and 34 women, mean age 41.32±3.71 years) suffering from primary KN OA. Study participants were randomly divided into three groups of 20 patients each. In the 1st group, a longacting GCs in combination with a local anesthetic was administered once i/a into the KN, in the 2nd – Armaviscon®Forte 2.3%, and in the 3rd – Armaviscon®Platinum 3%.Patients were examined at baseline, on the 14th and 60th day after a single injection of the drug. The intensity of pain was assessed on a visual analog scale (VAS), the Lequesne index, the KOOS, WOMAC, and EQ-5D questionnaires were used. When studying tolerability, the number of adverse reactions (ARs) was taken into account.Results. By the end of the observation period in the study groups, there was a decrease in the severity of pain and an increase in functionality with positive dynamics of the Lequesne and WOMAC indices. Both hyaluronic acid drugs had a positive effect on the functional state of the joints according to KOOS, improved the quality of life according to EQ-5D. The need for non-steroidal anti-inflammatory drugs in patients of the 2nd and 3rd groups decreased down to their complete cancellation. No adverse events requiring discontinuation of therapy have been reported. The advantage of i/a administration of hyaluronates in comparison with long-acting GCs was shown.Conclusion. In real clinical practice, in patients with symptomatic OA, i/a administration of hyaluronates allows obtaining more favorable results than the use of long-acting HA.Совершенствование терапии остеоартрита (ОА) коленных суставов (КС) остается актуальной проблемой.Цель исследования – сравнительная оценка эффективности и переносимости внутрисуставного (в/с) введения глюкокортикоидов (ГК) пролонгированного действия и гиалуронатов Армавискона®Форте и Армавискона®Platinum у пациентов с ОА КС.Материал и методы. С ноября 2019 г. по апрель 2022 г. проведено обследование и лечение 60 пациентов (26 мужчин и 34 женщин, средний возраст – 41,32±3,71 года), страдающих первичным ОА КС. Участники исследования были случайным образом разделены на три группы по 20 больных. В 1-й группе в КС однократно вводился ГК пролонгированного действия в сочетании с местным анестетиком, во 2-й – Армавискон®Форте 2,3%, а в 3-й – Армавискон®Platinum 3%. Пациентов обследовали исходно, на 14-й и 60-й дни после однократного введения препарата. Оценивалась интенсивность боли по визуальной аналоговой шкале, использовался индекс Лекена, опросники KOOS, WOMAC и EQ-5D. При изучении переносимости учитывали число неблагоприятных реакций (НР).Результаты и обсуждение. К моменту завершения наблюдения в исследуемых группах отмечались уменьшение выраженности боли и расширение функциональных возможностей с положительной динамикой индексов Лекена и WOMAC. Оба препарата гиалуроновой кислоты оказывали положительное влияние на функциональное состояние суставов по KOOS, улучшали качество жизни по EQ-5D. Потребность в нестероидных противовоспалительных препаратах у пациентов 2-й и 3-й групп уменьшалась вплоть до полной их отмены. НР, требующие прекращения терапии, не зарегистрированы. Показано преимущество в/с введения гиалуронатов по сравнению с ГК пролонгированного действия.Заключение. В реальной клинической практике у пациентов с симптоматическим ОА в/с введение гиалуронатов позволяет получать более благоприятные результаты, чем использование ГК пролонгированного действия

    Plant species richness records in Ukrainian steppes

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    We compiled a list of the known maxima of vascular plant species richness in the steppe zone of Ukraine at different sampling scales (0.0001–100 m2) and compared them with the world records. Detailed information on each of the identified species-rich grassland plots is provided, including site descriptions, plot characteristics, coordinates, and species lists. Most of the small-scale records (up to 0.1 m2) were found in mesic grasslands in southern Ukraine (Kherson region) with a high abundance of annual grasses and forbs: 9 and 11 vascular plant species in 0.0001 m2 and 0.001 m2, respectively, in the steppe depression Chorna Dolyna, and 26 species in 0.1 m2 in a mesic psammophytic grassland in the Dzharylhach National Nature Park. Most of the records at larger scales were made in the northern part of the steppe zone, in forb-rich and forb-grass steppes: 15, 39, 73, and 107 species in 0.01, 1, 10, and 100 m2, respectively. All richness records were characterised by neutral to slightly alkaline sub-strates (soil pH 7.0–7.7) and low-intensity management. These characteristics are consistent with the known patterns from world records of species richness. Our inventory provides baseline knowledge for studies on the high species richness in the steppe zone and can stimulate the further investigation of identified species-rich grasslands, as well as the search for new ones. Since we did not specifically search for species-rich sites, and our dataset includes only a relatively small number of plots compared to similar studies in other regions, we expect that more species-rich vegetation will be found with further research. This study highlights the importance of steppe grasslands as global biodiversity hotspots and draws attention to their protection in the context of land-use changes and the consequences of the war in Ukraine

    Gentle method of treatment of closed diaphyseal fractures of the tibia bones in elderly and old people

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    The Department of Traumatology, Orthopedics, and Military Field Surgery of the Sechenov Moscow Medical Academy. I.M. Sechenov Moscow Medical Academy and its clinical base, Hospital No. 67, have developed and put into practice a method of extrafocal fixation of fragments in closed diaphyseal fractures of the tibia bones in the elderly and elderly; its use in combination with functional treatment techniques during fracture healing makes it possible to minimize postoperative complications and significantly reduce the rehabilitation period of patients.</jats:p

    Аналіз причин падіння баштового крану кб-674а

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    Abstract. In the manuscript given a modern real estate market, the means of construction works, particularly the use of tower cranes, ensure safe conditions of installation and use. The  requirements  of  regulations to  ensure  the  stability  and  durability  of  cranes  as  in  general  whole  and  metal  structures  and mechanisms, formulated purpose of the article contained an expanded main part where given specific materials of primary survey site of the accident, testimony, analysis of the project of works, recordings of the sections of the passport crane engineering calculations of the stability of the crane with the necessary illustrations and results of calculations. The evaluation of the violations of the provisions of the owner of the crane regulations of occupational safety, project designers, installation work, fitters, crane when performing installation and set out measures to prevent  such accidents and accidents.В рукописи статьи приведено состояние  современного рынка жилой недвижимости, средства выполнения строительных  работ,  особенности  использования  башенных  кранов,  обеспечение  безопасных  условий  монтажа  и использования.  Приведены  требования  нормативных  документов  по  обеспечению  устойчивости  и  прочности  кранов  в целом и их металлоконструкций и механизмов в частности; сформулирована цель статьи; приведены конкретные материалы первичного обзора места аварии, свидетельские показание, анализ проекта производства работ, записи из разделов паспорта крана,  технические  расчеты  устойчивости  крана  с  необходимыми  иллюстрациями  и  результатами  расчетов.  Проведена оценка допущенных  владельцем крана  нарушений  положений правовых актов  охраны  труда, проектировщиками – проекта производства  монтажных  работ,  монтажниками  крана  –  при  выполнении  монтажных  работ;  сформулированные  меры  к предотвращению подобных аварий и несчастных случаев.В  рукописі  статті  наведений  стан  сучасного  ринку  житлової  нерухомості,  засоби  виконання  будівельних робіт, особливості використання баштових кранів, забезпечення безпечних умов монтажу та використання. Наведені  вимоги  нормативних  документів  щодо  забезпечення  стійкості  та  міцності  кранів  в  цілому  та  їх металоконструкцій та механізмів, сформульована мета статті, наведена розширена основна частина, де приведені конкретні матеріали первинного огляду місця аварії, показання свідків, аналіз проекту виконання робіт, записів із розділів паспорту крана, технічні розрахунки стійкості крана із необхідними ілюстраціями та результати розрахунків. Проведена оцінка допущених власником крана порушень положень правових актів із охорони праці, проектувальниками – проекту виконання монтажних робіт, монтажниками крана – при виконанні монтажних робіт та сформульовані заходи що до запобігання подібних аварій та нещасних випадків

    Comparative evaluation of the efficacy and safety of intra-articular administration of hyaluronic acid and glucocorticoids in the complex therapy of osteoarthritis

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    Improving the treatment of knee (KN) osteoarthritis (OA) remains an urgent problem.Objective: to compare the efficacy and tolerability of intra-articular (i/a) administration of long-acting glucocorticoids (GCs) and Armaviscon®Forte and Armaviscon®Platinum hyaluronates in patients with knee OA.Material and methods. From November 2019 to April 2022, we examined and treated 60 patients (26 men and 34 women, mean age 41.32±3.71 years) suffering from primary KN OA. Study participants were randomly divided into three groups of 20 patients each. In the 1st group, a longacting GCs in combination with a local anesthetic was administered once i/a into the KN, in the 2nd – Armaviscon®Forte 2.3%, and in the 3rd – Armaviscon®Platinum 3%.Patients were examined at baseline, on the 14th and 60th day after a single injection of the drug. The intensity of pain was assessed on a visual analog scale (VAS), the Lequesne index, the KOOS, WOMAC, and EQ-5D questionnaires were used. When studying tolerability, the number of adverse reactions (ARs) was taken into account.Results. By the end of the observation period in the study groups, there was a decrease in the severity of pain and an increase in functionality with positive dynamics of the Lequesne and WOMAC indices. Both hyaluronic acid drugs had a positive effect on the functional state of the joints according to KOOS, improved the quality of life according to EQ-5D. The need for non-steroidal anti-inflammatory drugs in patients of the 2nd and 3rd groups decreased down to their complete cancellation. No adverse events requiring discontinuation of therapy have been reported. The advantage of i/a administration of hyaluronates in comparison with long-acting GCs was shown.Conclusion. In real clinical practice, in patients with symptomatic OA, i/a administration of hyaluronates allows obtaining more favorable results than the use of long-acting HA.</jats:p

    THE FEATURES OF PRETERM PERIOD AND DELIVERY IN PPATIENTS WITH BENIGN OVARIAN NEOPLASMS

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    Abstract: Nowadays medical society is facing increasing numbers of adnexal masses in women of reproductive age, and especially challenging for the diagnostic workup and management are such cases during the pregnancy. Our study has a primary focus on the specific features of the pregnancy and delivery in patients with benign ovarian neoplasms.Materials and methods: This is a retrospective study that included 88 pregnant patients with benign ovarian neoplasms that delivered in our facility during the period from 2014 to 2016. The patients were divided into two groups, the 1st group included 45 pregnant women with endometrioid ovarian cysts, the 2nd group consisted of 43 pregnant women with cystadenomas and ovarian teratomas. As a control group, we used cumulative statistical data from our facility and several related organizations, representing the general population.Results: It was observed, that the odds ratio of the threatened miscarriage and the threat of preterm delivery was significantly higher in patients with endometrioid ovarian cysts compared to the general population. However, the frequency of complications of the preterm period and delivery in patients with cystadenomas and ovarian teratomas showed no significant difference, compared to populational data. There were no significant differences in complications between patients with endometrioid ovarian cysts and cystadenomas / ovarian teratomas.Conclusion: Our research provides additional data on pregnancies with adnexal masses, which can help in the prevention of complications and choosing the modality of treatment in pregnant patients.</jats:p
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