Commercial Speech Law and Tobacco Marketing: A Comparative Discussion of the United States and Canada

Published by the American Society of Law, Medicine & Ethics and Boston University School of Law

Manipulative Marketing and the First Amendment

First published in The Georgetown Law Journal

The Role of World Knowledge and Episodic Memory in Scripted Narratives

Readers recruit information from both general world knowledge and episodic memory during reading comprehension. The present experiment used eye tracking to investigate the time-course of how these two sources of memory interact. Participants read passages describing scenarios in which an actor performs a role that was either scriptually appropriate or inappropriate. Half the passages containing the inappropriate role-filler were preceded by an episodic justification for this scriptural violation. Using the same paradigm, Cook and Myers (2004) found context had an early influence on the integration of the role-filler, but world knowledge showed a later effect in the post-target region. The present experiment expands upon these results by adding a backgrounding section between the episodic justification and the role-filler that reduces the saliency of the episodic information. Evidence of integration difficulties were observed in both early and late processing measures. These results appear to favor a two-stage model of processing: the first stage links incoming information with the contents of active memory; the second stage evaluates the link between the old and new information

Detection of bacterial spores with lanthanide-macrocycle binary complexes

The detection of bacterial spores via dipicolinate-triggered lanthanide luminescence has been improved in terms of detection limit, stability, and susceptibility to interferents by use of lanthanide−macrocycle binary complexes. Specifically, we compared the effectiveness of Sm, Eu, Tb, and Dy complexes with the macrocycle 1,4,7,10-tetraazacyclododecane-1,7-diacetate (DO2A) to the corresponding lanthanide aquo ions. The Ln(DO2A)^+ binary complexes bind dipicolinic acid (DPA), a major constituent of bacterial spores, with greater affinity and demonstrate significant improvement in bacterial spore detection. Of the four luminescent lanthanides studied, the terbium complex exhibits the greatest dipicolinate binding affinity (100-fold greater than Tb^(3+) alone, and 10-fold greater than other Ln(DO2A)^+ complexes) and highest quantum yield. Moreover, the inclusion of DO2A extends the pH range over which Tb−DPA coordination is stable, reduces the interference of calcium ions nearly 5-fold, and mitigates phosphate interference 1000-fold compared to free terbium alone. In addition, detection of Bacillus atrophaeus bacterial spores was improved by the use of Tb(DO2A)^+, yielding a 3-fold increase in the signal-to-noise ratio over Tb^(3+). Out of the eight cases investigated, the Tb(DO2A)^+ binary complex is best for the detection of bacterial spores