Ordering in Heisenberg Spin Glasses

For five different Heisenberg spin glass systems, torque experiments were performed in applied magnetic fields up to $4 T$. The Dzyaloshinski-Moriya random anisotropy strengths, the in-field torque onset temperatures, and the torque relaxation were measured. Critical exponents were estimated independently using a standard protocol. The data are strong evidence for a true spin glass ordered state which survives under high applied magnetic fields; they can be interpreted consistently in terms of a chiral ordering model with replica symmetry breaking as proposed by Kawamura and coworkers.Comment: 4 pages 4 figures. Revised version accepted by PR

Relativistic theory for time and frequency transfer to order c^{-3}

This paper is motivated by the current development of several space missions (e.g. ACES on International Space Station) that will fly on Earth orbit laser cooled atomic clocks, providing a time-keeping accuracy of the order of 5~10^{-17} in fractional frequency. We show that to such accuracy, the theory of frequency transfer between Earth and Space must be extended from the currently known relativistic order 1/c^2 (which has been needed in previous space experiments such as GP-A) to the next relativistic correction of order 1/c^3. We find that the frequency transfer includes the first and second-order Doppler contributions, the Einstein gravitational red-shift and, at the order 1/c^3, a mixture of these effects. As for the time transfer, it contains the standard Shapiro time delay, and we present an expression also including the first and second-order Sagnac corrections. Higher-order relativistic corrections, at least O(1/c^4), are numerically negligible for time and frequency transfers in these experiments, being for instance of order 10^{-20} in fractional frequency. Particular attention is paid to the problem of the frequency transfer in the two-way experimental configuration. In this case we find a simple theoretical expression which extends the previous formula (Vessot et al. 1980) to the next order 1/c^3. In the Appendix we present the detailed proofs of all the formulas which will be needed in such experiments.Comment: 11 pages, 2 figures, to appear in Astronomy & Astrophysic

Gyroless Ball: Estimation Of Angular Velocity Without Gyroscope

In [MP15a, MP15b], an algorithm is proposed to estimate the angular velocity of a rigid body using only vector measurements (i.e. measurements of unknown but constant directions). The cases of a single and two vectors measurements have been addressed using similarly structured state-observers. In this note, we report experiments conducted on one such rigid body, here a wood ball, which is equipped with a smartphone. The direction sensors of the smartphone (magnetometer and accelerometer) are used in the algorithm and the angular rate estimate is compared against the readings from the smartphone gyro. Although neither the magnetic field nor the field sensed by the accelerometer are constant, the estimation algorithm works well. The experiments were conducted on August 26th, 2015 and have been presented at the Congr es Français de Mécanique 2015. A video can be found on YouTube: https://youtu.be/L8fNeH347C

The effects of donepezil in Alzheimer's disease - Results from a multinational trial

Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD). The current trial was undertaken to investigate further the efficacy and safety of donepezil, in a multinational setting, in patients with mild to moderately severe AD. This 30-week, placebo-controlled, parallel-group study consisted of a 24-week, double-blind treatment phase followed by a 6-week, single-blind, placebo washout. Eight hundred and eighteen patients with mild to moderately severe AD were randomly allocated to treatment with single, daily doses of 5 or 10 mg donepezil, or placebo. The two primary efficacy measures were: a cognitive performance test, the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) and a global evaluation, the Clinician's Interview-Based Impression of Change with caregiver input (CIBIC plus). Secondary outcome measures included the Sum of the Boxes of the Clinical Dementia Rating Scale (CDR-SB), a modified Interview for Deterioration in Daily living activities in Dementia (IDDD) and a patient-rated quality of life assessment. Statistically significant improvements in cognitive and global function were observed, as evaluated by ADAS-cog and CIBIC plus, respectively, in both the 5 and 10 mg/day donepezil groups, compared with placebo. Treatment-associated changes were also observed in functional skills, as shown by improved scores on the CDR-SB and the complex-tasks component of the IDDD. A dose-response effect was evident, with the 10 mg/day donepezil group demonstrating greater benefits in all outcome measures than the 5 mg/day group. Donepezil was well tolerated by this patient population and did not produce any clinically significant laboratory test abnormalities. The results of this study confirm that donepezil is effective and well tolerated in treating the symptoms of mild to moderately severe AD

Retrospective Analysis of Wood Anatomical Traits Reveals a Recent Extension in Tree Cambial Activity in Two High-Elevation Conifers

The study of xylogenesis or wood formation is a powerful, yet labor intensive monitoring approach to investigate intra-annual tree growth responses to environmental factors. However, it seldom covers more than a few growing seasons, so is in contrast to the much longer lifespan of woody plants and the time scale of many environmental processes. Here we applied a novel retrospective approach to test the long-term (1926–2012) consistency in the timing of onset and ending of cambial activity, and in the maximum cambial cell division rate in two conifer species, European larch and Norway spruce at high-elevation in the Alps. We correlated daily temperature with time series of cell number and lumen area partitioned into intra-annual sectors. For both species, we found a good correspondence (1–10 days offset) between the periods when anatomical traits had significant correlations with temperature in recent decades (1969–2012) and available xylogenesis data (1996–2005), previously collected at the same site. Yet, results for the 1926–1968 period indicate a later onset and earlier ending of the cambial activity by 6–30 days. Conversely, the peak in the correlation between annual cell number and temperature, which should correspond to the peak in secondary growth rate, was quite stable over time, with just a minor advance of 4–5 days in the recent decades. Our analyses on time series of wood anatomical traits proved useful to infer on past long-term changes in xylogenetic phases. Combined with intensive continuous monitoring, our approach will improve the understanding of tree responses to climate variability in both the short- and long-term context